10 20 30 40 50 60 70 80 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....| gi 19075551 273 SRDLQVEKLSVSA--WGKLLIKDSELNLINGRRYGLIAPNGSGKSTLLHAIA----------CGLIPTPSS-LDFYLLDR 339 gi 19552636 3 KTHIRLQDLSLSY--TSTPLITKLNITVSSGQCAVIVGENGRGKTTLLRALAref----ppsAGEILTHGT---VAIAHQ 73 gi 19173659 1 -MSSKISSLKHKY---LRKLERFPFESKEEATRVGVGGCTVGYTRGLVPLETpfsmrsvrgrKEIVVPDAP-IQEEYLSS 75 gi 15672881 1 MSNIEFKDLTFGY--GDNLIFNHAQINIDDRWKLGLVGRNGRGKSTLLNLLQgki-----ttDSSITTDKNfVYFPQLLT 73 gi 15827973 1 MITATDLEVRAGA--RILLSSDGPDLRVQPGDRIGLVGRNGAGKTTTLRILAgat----epyAGSVTWTG---EIGYLPQ 71 gi 15829161 1 --MLEVQGLSKIF--SDKKLFENVNLKFTEGNVYGIIGANGAGKSTFLKILAgti----eqtSGTILKEKN-KRISTLGQ 71 gi 15608806 2 AHLLGAEAVHLAY--PTQVVFEAVTLGVNDGARIGIVGRNGDGKSSLLGLLTgql----rpdSGRVTRRSG-LRVNALSQ 74 gi 16263742 1 MPSITLSALSWSK--PDGEHVFSDLDLAFGPERTGLVGRNGIGKTSVLNIIAgtl----rpsSGTVAIQG---RVALARQ 71 gi 15901142 10 NHMIKINHLTITQnkDLRDLVSDLTMTIQDGEKVAIIGEEGNGKSTLLKILMgeals-dftiKGNIQSDYQ--SLAYIPQ 86 gi 19114521 442 eeELVNTDFSLAYg--GRLLLSHTNLHLYRGHRYGVVGHNGCGKSTLLRAIGdyk----venFPSPDEVKT-CFVAHSLQ 514
90 100 110 120 130 140 150 160 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....| gi 19075551 340 EYIPNEL------TCVEAVLDINEQERKHLEAMMEDLLDDPDK---------NAVELDTIQTRLTDLET----------- 393 gi 19552636 74 HMPAGDL------SVGEICDEAIRDSKNALEELERAGALLETN---------TAHALDGYQQALDAAEVld--------- 129 gi 19173659 76 SSSGEDTdsegfeGDLHLVIDLFVKGKEIIREAPLTIVRGRKYglvgrngigKTTLLKAIRKRRFGIPRgmriymikqdl 155 gi 15672881 74 EEDFNDKd-----KSKKQNTADKYSVESLSVKITDRNS----------------QLTYYVLNELAEFEQ----------- 121 gi 15827973 72 DPKVGNLd-----VLARDRVLSARGLDVLLTDLEKQQALMAEVadd----daRDRAIRRYGQLEERFLAlgg-------- 134 gi 15829161 72 NHNEFDDe-----IVTDVVIMGNDVLYEIKNKKDAIYN-NPDAte------kDYTLASELEEKYGEMGG----------- 128 gi 15608806 75 TDTLDPNr-----TVGWTLIGDQ-------PEHQWAGNP----------------------------------------- 101 gi 16263742 72 ILRAG-Ad-----ETIADVFGATQAVAVLRRAEKGDASVe--------------------------eLEtad-------- 111 gi 15901142 87 KVPED---------LKKKTLHDYFFLDSIDLDYSILYR------------------------------------------ 115 gi 19114521 515 GEDTSm---------------------------------------------------AILDFVAQDKAll---------- 533
170 180 190 200 210 220 230 240 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....| gi 19075551 394 ---ENSD----HRVYKILRGLQFTDEmiAKRTNELSGGWRMRIALARILFIKPT----------LMMLDEPTNHLDLEAV 456 gi 19552636 130 --aWNAE----HRLEKALRSFGAITDr-SRALSELSIGQRYRVRLACLIGGDAD----------ILLLDEPTNHLDRGAL 192 gi 19173659 156 ivdETVEdfagAEAGRILNGLGFTKDmaVKNMRDLSGGWRMRAHLAKAINADPD----------LLLLDEPTNYLDINAL 225 gi 15672881 122 ---WKLEr----ELSLLKVDLEILWR----PFGSLSGGEQTKCLLAILFLDEDN----------FPLIDEPTNQLDLESR 180 gi 15827973 135 -ysAESE----AGRICASLGLPERVL--VQQLCTLSGGQRRRVELARILFAASRagtgasgsgtTLLLDEPTNHLDADSL 207 gi 15829161 129 ---WNAE----NDAQVLLSSLTIDKDkwYLKMKELKANEKVKVLLAKALFGNPD----------ILIMDEPTNHLDLKSI 191 gi 15608806 102 ------R----IRDVVAGL-VSDIAW--DTPVSTLSGGQRRRVQLASLLVGEWD----------VIALDEPTNHLDIQGI 158 gi 16263742 112 -wtVEER----IVSALARLGL-EARA--DTLLNQLSGGQRTRAVLAAAIFSEPD----------FLLLDEPTNNLDRDGR 173 gi 15901142 116 -----------LAEELHFDSNRFAS---DQEIGNLSGGEALKIQLIHELAKPFE----------ILFLDEPSNDLDLETV 171 gi 19114521 534 -tmNVTR----QEAADALHSVGFTAEmqENPVASLSGGWKMKLELARAMLQKAD----------ILLLDEPTNHLDVANI 598
250 260 270 280 290 300 310 320 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....| gi 19075551 457 AWLEEYLThEMEGh---TLLITCHTQDTLNEVCTDIIHLYHQ-------------------------KLDYYSG-NYDTF 507 gi 19552636 193 NYLTEAIT-SHKG----VVLVVSHDQALIKDVADFIIDIDSTp-----------------------dGLPRIYHeGFDSY 244 gi 19173659 226 SWLEGKIK-ELKT-----VIIVSHDRNFLNNTTEMILHLNDL-------------------------KIDVYRG-NYESF 273 gi 15672881 181 KIVADYLQ-KKSG-----FIVVSHDRNFLDEVCDHTLAIERQ-------------------------QIVLYQG-NFSTY 228 gi 15827973 208 GWLRDFLR-SHTG----GLVVISHNVELIAAVVNRVWFLDAvlg---------------------kvDVYNMG---WYKY 258 gi 15829161 192 KWLENFLA-NYPN----VVIVVSHDSDFLDEVCSHIVDIDFG-------------------------EAKIFTG-NYSFW 240 gi 15608806 159 TWLADHLR-RRWArntgGLLVVTHDRWFLDEVATTTWEVHDG-------------------------IVEPFEG-GYAAY 211 gi 16263742 174 RAVIGLLS-GWRS----GAIVVSHDRELLEEMDAIIELTSLGtkrygggwsayqaaraveleaaqqsLTLARKT-ADEVD 247 gi 15901142 172 DWLKGQIQkTRQT-----VIFISHDEDFLSETADTIVHLRLVkhr--------------------keAETLVEHlDYDSY 226 gi 19114521 599 AWLEAYLT-SQKNi---TCLIVSHDSSFLDHVCTDIIHYEGVknq--------------------akKLGYYQG-NLSAF 653
330 340 350 360 370 380 390 400 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....| gi 19075551 508 LKVRAERD--------VQLAKKARQ-------QEKDMAKLQNKLNMTGSEQQKKa-----kAKVKAMNKKLEKDKQSg-- 565 gi 19552636 245 RRQRSALLet-----wRQDYAAAQTv------QQQLQEDLEHARQRVNSSWKPP--------KGTGKHTRASRAPGv--- 302 gi 19173659 274 VKQRKEKT--------ASARREYES-------QLLVREHMQSFIDRFRYNAKRAs-------LVQSKIKMLAKMP----- 326 gi 15672881 229 EREKQLRD--------DFELAEDEKlrkdisrLKKTSLEKRDWSNQRENVAGATfvdkkvaKKQNQRAKSIEKRMGQeve 300 gi 15827973 259 LDSRATDE--------QRRRRER---------VNAERKATALRTQAAKMGAKAtk-----aVAAQNMLRRADRMMAA--- 313 gi 15829161 241 KESSELAL--------ELRKQSNLK-------KEEQIQKLQSFIARFSSNLSKS-------SQATSRKKALEKIT----- 293 gi 15608806 212 VLQRVERD--------RLTAAAEAK-------RQNLLRKELAWLRRGAPARTC---------KPKFRIEAANQLIAD--- 264 gi 16263742 248 RKARALAE--------RLDKRDASG-------TRKAAKGDMPRILVGRRKSNAEesrgksvELAERRRAGALDAVTA--- 309 gi 15901142 227 SEQRKANFak-----qSQQAANNQRaydktmeKHRRVKQNVETALRATKDSTAGrl---laKKMKTVLSQEKRYEKAa-- 296 gi 19114521 654 VKVKPEAKsyytltatNEKFVFPPPgil--tgVRSNTRLILKMTNASYTYPNAk-------KKSLDNVTVGLSLSSR--- 721
410 420 430 440 450 460 470 480 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....| gi 19075551 566 --KVLDEEIIQEKQLVIRFEDCGG--------------GIPSPAIKFQDVSFNYPGG---PTIFSKLNFGLDLKSRVALV 626 gi 19552636 303 -vQALKRAQDALDSKALDVPPAPAp------------lLLPTLKVRPDKPMVDFSDLfvpHRLRLPGSHSVVSGDKIVIT 369 gi 19173659 327 ---TLVAPKQ-DPVIKFTFSSTP----------------AQGALIEFVNVVFSYGCG----KVLGGLSMKINSDSRIVVV 382 gi 15672881 301 nkEKLLKNIEKTEPLIMNFQPSHH-----------------KRLIQFENFSLGFTEK----LLFQPIDFSLKVGEIAAIV 359 gi 15827973 314 --LDEERVIEKVAQI--KFPTP----------------AACGRTPLVAKGLSKTYGS---LEVFTGVNLAIDRGSRVVVL 370 gi 15829161 294 --LDEIKPSSRKYPF-IKWEINR---------------VPGKQILNVENLSYVNKKGe---VLFENVSFSLKLGEKLVII 352 gi 15608806 265 --VPPPRNTVELAKL--AAARLGK--------------DVVDLLGVSVSYQPSG--G---RPVLRDIEWRIGPGERIGIV 321 gi 16263742 310 --AKARIEVLQPFSI--RLPRTEL--------------PAGRQVLAFDGVTAGYDPA---RPIIRDLSFSLVGPRRVSVT 368 gi 15901142 297 --QSMTQKPLEEEQIQLFFSDIQPl-------------PASKVLVQLEKENLSIDDR----VLVQKLQLTVRGQEKIGII 357 gi 19114521 722 --VAILGPNGAGKSTLIKVLIGEVipqegkvfkhpnlrVGYVAQHAFHHLDQHLEKTp-sQYIQWRYAGGQDREVSEKES 798
490 500 510 520 530 540 550 560 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....| gi 19075551 627 GPNGAGKTTLIKLILEKVQPS---TGSVVRHHG-LRLALFNQHMg------DQLD----MRL-------SAVEWLRTKFG 685 gi 19552636 370 GDNGAGKSTLIEVLSGVLTPA---SGSVANHAR---TGVLGQES--------LVG---------------------EVP- 413 gi 19173659 383 GANGQGKSTFLKLLAGKLEAT---EGSIIRAPS-LRVGYFAQHHi------DHLRv---NEN--------VLDFMMKSY- 440 gi 15672881 360 GPNGQGKSSIFKYLSGDFSGEh--SGFVQFPQG-IRLSFVRQIY-------DNRG--------------YLKDFATEYQL 415 gi 15827973 371 GLNGAGKTTLLRVL--AGAEKp-dVGRLEPGHG-LRIGYFAQEH-------DTLDn---EDT-------VWQNIRHTAP- 428 gi 15829161 353 GNDDLAKTKLIEVILGIEKPS---SGKVEWGQT-IKTSYFPLNN-------DNYFn---NDL-------SILDWISQFPL 411 gi 15608806 322 GANGAGKSTLLGLI---AGTVqp--------------------------------------------------gVGRVKP 348 gi 16263742 369 GPNGSGKTSLLKVV---TGELppfKG--TVSVN-VPFTLLDQSV-------SILEr---GET-------ILENFKRLNP- 424 gi 15901142 358 GPNGVGKSTLLAKL----------QRLLNDKRE-ISLGFMPQDYh------KKLQ----LDL-------SPIAYLSKTGE 409 gi 19114521 799 RKLTEEDRAQLQRDITVN-GErrrVEALIGRQKlKKSFQYEIKWfgkphkyNTWVsreiLLEngfqkfvQAFDDMESSRE 877
570 580 590 600 610 620 630 640 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....| gi 19075551 686 NKP--------EGEMRRIVGRYGLTGKSQ-VIPMGQLSDGQRRRVLFAFLGMT--QPHILLLDEPTNALDIDTIDALADA 754 gi 19552636 414 ------------SIARDHAVKWGLLSVEEsRFALQEFSIGQRRRLDLAMSLAG--NPELLLLDEPSNHLSMHLVSALTEW 479 gi 19173659 441 --T--------QEEARRALASFGLSVDNQ--CIG-TLSGGQKSRLGFAIINGL--SPNLLVLDEPTNHLDMESIDALAEA 505 gi 15672881 416 N----------YELFLANLRKLGMECKQF-SQKIETMSQGQQKKVELARSLSQ--EAELYLWDEPLNYLDVFNREQIIQL 482 gi 15827973 429 --Efg------eqDLRGLLGAFMFSGPQL-DQLAGTLSGGEKTRLALAGLVAS--TANVLLLDEPTNNLDPASRKQVLDA 497 gi 15829161 412 TNEleankdnsDHRMRSFLGRMLFSGETV-FKRVNVTSGGEKARLMFSKMMLE--ESNFIILDQPLDHLDTESIDSVIKG 488 gi 15608806 349 SGWqc------sISTGTIWHRLPTTGSPM-C------------------------------------------------- 372 gi 16263742 425 --Gas------dnACRAALASFRFRADAA-LQRVEALSGGQVLRAGLACALGGsdPPSLLILDEPTNHLDIDSIEAVEAG 495 gi 15901142 410 KEE--------LQKIQSHLASLNFSYPEM-QHQIRSLSGGQQGKLLLLDLVLR--KPNFLLLDEPTRNFSPTSQPQIRKL 478 gi 19114521 878 GLGfre---liPEDIRAHFEDVGLPGDIAdYSPISSLSGGQKVKVVIAACLWN--NPQLLVLDEPTNFLDRDALGGLAVA 952
650 660 670 680 690 ....*....|....*....|....*....|....*....|....*....|... gi 19075551 755 LNNFDGGVVFITHDFRLIDQVA-EEIWIVQNg--TVKEFDGEIRDYKMMLKQQ 804 gi 19552636 480 LDTTAAAVIMVTHDRQLLRDTAhWRHIELKS---------------------- 510 gi 19173659 506 LGRFNGAVVCVSHDLSFISSAF-REIYICEDg--SIRRFYGDILEYKKGLGV- 554 gi 15672881 483 LETYHPTMLLVEHDQAFVEKIS-NQIINLKDt--------------------- 513 gi 15827973 498 LRNYQGAVVLVTHDPGAAKALD-PQRVVLLPdgtEDYWS-DEYRDLIELA--- 545 gi 15829161 489 LKEYKSSCIFTTYNRALIKKVA-NVILELKEn-eSYIFR-VNLDEYEKAMGY- 537 gi 15608806 ----------------------------------------------------- gi 16263742 496 LLSYDGALVVVSHDETFLANIG-IGTRVELSt-sRG----------------- 529 gi 15901142 479 FATYPGGLITVSHDRRFLKEVC-SIIYRMTEhglKLVNLEDL----------- 519 gi 19114521 953 IRDWEGGVVMISHNEEFVSALC-PEHWHVE----AGKVTGKGKTAVDDGKFED 1000
