1AYE,3GLJ


Conserved Protein Domain Family
Propep_M14
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pfam02244: Propep_M14 (this model, PSSM-Id:308061 is obsolete and has been replaced by 460505)
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Carboxypeptidase activation peptide
Carboxypeptidases are found in abundance in pancreatic secretions. The pro-segment moiety (activation peptide) accounts for up to a quarter of the total length of the peptidase, and is responsible for modulation of folding and activity of the pro-enzyme.
Links
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Statistics
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PSSM-Id: 308061
Aligned: 378 rows
Threshold Bit Score: 45.2432
Created: 17-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1AYE_A        10 LEIV--PSNEEQIKNLLQLEaqEHLQLDFWKSPTTPGETAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKE 84  human
CCE30178      34 FRIP--VADEEDGLLMQNLV--DKLGLAVWQPPSKKGAFADMQVPADQLRAFGKAMEHRNV--IIMHEDLGKSIRNE 104 Claviceps purpurea...
XP_002541806  32 FRI---PTTEENHARVVDLI--NELHLDTWKFPKKVGFAADVVVPLEQISSFEK--ATAGLTIEVMHEDLGASIEAE 101 Uncinocarpus reesi...
KDB25014      28 YKVIrvPTQKDNVKEVQRII--TDLNLDTWKYPKSEGQNADIVVPPSQITSFME--RISGMSMEMMHEDLGMSISNE 100 Trichophyton inter...
XP_001587947  31 YRLK--AQNDN-IEKINDIV--SSLDLQTWKKSAKLG-TADVVVPPEHVDNFLRITE--DMQREVMHSNLGESIAEE 99  Sclerotinia sclero...
CCX32640      36 viriqldDNQAKTDQVRAMI--QKMDLETWTNGYKPNRLVDVVVEPSKIAAFDSDCGLNGIQYTTMHEDLGKSIREE 110 Pyronema omphalode...
KFG78725      31 FRVR--IADDG--SHVRSVI--DKLQLTTWQPPSRKGAFADIQVAPRQLEEFHKAMEGQDLT--TMHDDLGKSIKRE 99  Metarhizium anisop...
XP_006692386  36 FRVD--VENEAVAERLNKVI--DTLGLSTWKARPRAGYTADIVVPPTALLQFES--EVADLKTMTMHEDLEKSIEEE 106 Chaetomium thermop...
XP_003839555  33 VNVG--T----NAAKFNDVV--SKLKLEVWKGKPAASEVVDVVVPPTQISEFEA--STAELKTQVMHENLGLSIADE 99  Leptosphaeria macu...
XP_002585155  30 vvRI--PTEEDNHAQVVKVI--ENLKLDTWKFPKRAGSDADIVIPPEQLEAFNK--AIAGLKVEIMHEDLGASIEDE 100 Uncinocarpus reesi...
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