Conserved Protein Domain Family
RRP14
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pfam15459: RRP14 (this model, PSSM-Id:292098 is obsolete and has been replaced by 464729)
60S ribosome biogenesis protein Rrp14
RRP14 is a family of nucleolar 60S ribosomal biogenesis proteins from eukaryotes. RRP14 functions in ribosome synthesis as it is required for the maturation of both small and large subunit rRNAs and it helps to prevent premature cleavage of the pre-rRNA at site C2. It also plays a role in cell polarity and/or spindle positioning.
Links
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Statistics
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PSSM-Id: 292098
Aligned: 55 rows
Threshold Bit Score: 39.5341
Created: 17-Jul-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q5KN02        14 SLEKHNAAFTTLLSLIPAQYYIAAD---PEVADS-KWMKNKKRKTGEEI-KENKKKV--KQA----KLDPS 73  Cryptococcus neoformans
XP_001759133  12 aVHSHAVFFDRLVEMIPANIYVPKEnptDQ-WAH-GMSKKARAESKRKT-KLNLKKA--KRA----RLDPE 73  Physcomitrella patens
XP_002968293  11 iVRANSRYFDELVDLIPPKFYLPADdnvEKQWVF-GMTKREKREARRLT-KEHSKKA--RRD----RLDPE 73  Selaginella moellendorffii
XP_012894193   7 iIHGHALFFDEVLERIPASLYLAPTeeeNQKWKK-GFKKNNNDQRKAEL-KESAQKK--RKE----RFDPE 69  Blastocystis hominis
GAA97914       6 SLIAHNASFEALLSLIPAKLYLREEhatEMEDLS-GLSKKQRKKRQAEL-AEESKQV--KRAakmsRFDPE 72  Mixia osmundae IAM 14324
XP_003056819   9 RVHQHSDFFDRLVELIPAKYYVPDEqnpEWSKFN-K-TKSAKAAAKQEA-KENSKKA--LRA----KLAPg 70  Micromonas pusilla CCMP1545
XP_002508799   8 RVAGHSDFFDRLVELIPARYYVPDEanpEWSKFQ-K-TKSAKAAAKQAA-KENSKKA--LRA----KLQPg 69  Micromonas sp. RCC299
XP_008906099  24 tLKTHDRFFCETMEIIPAAFYFPTDaetNWKKSA--PKKYHKNVQALKQ-QESSKKNllKRA----KFSPA 87  Phytophthora parasitica ...
XP_006958525   3 DLSEINNNFLELLSFIPENLYSHKEinlDE-----KYFKKSSNASKLQL-KLNKQKS--LRE----KLDPv 61  Wallemia sebi CBS 633.66
XP_007410759  13 SLLGHDREFQRLLCMIPSKFHVLPP---DQSLLDeGFSKKSKKHKNQKItPEEKRLQ--KRA----RFDPD 74  Melampsora larici-populi...
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