Conserved Protein Domain Family
MotB_plug

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pfam13677: MotB_plug 
Membrane MotB of proton-channel complex MotA/MotB
This is the MotB member of the E.coli MotA/MotB proton-channel complex that forms the stator of the bacterial membrane flagellar motor. Key residues act as a plug to prevent premature proton flow. The plug is in the periplasm just C-terminal to the MotB TM, consisting of an amphipathic alpha helix flanked by Pro-52 and Pro-65. In addition to the Pro residues, Ile-58, Tyr-61, and Phe 62 are also essential for plug function.
Statistics
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PSSM-Id: 290401
View PSSM: pfam13677
Aligned: 345 rows
Threshold Bit Score: 27.0829
Threshold Setting Gi: 242123752
Created: 30-Jun-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

pfam13677 is a member of the superfamily cl16345.
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 81741410    4 RGKKK----SQSHMDESWLLPYADLLTLLVALFIVLFAMSDINIQKYEQLASVFRSEF 57
gi 501119932  13 IKRHEd--eEHEHHSSAWKVAHADFMTAMMAFFLIMWLINVTDKDVRKAIASYFNPvh 68
gi 501209369  11 IKRHGd--hEEGHHGGAWKIALADFMTAMMALFLVMWLINSTSKEQKQTIAEYFNPvk 66
gi 504015863  13 KRHLGg--hEEEEHNGTWKLAYADFVTAMMTFFLVMWLMNITTTEQRKGIADYFNPva 68
gi 518928411  17 RRRGGd--gEEGHHGGAWKIAFADLMTAMMAFFLVMWLLNVSDKEKIQQIATYFNPlk 72
gi 754167347   3 RKKLYr--sDGDNHGGVWKIAYADFMTAMMTFFLVMWLVNSSSKERLSQIANYFNPvk 58
gi 494821737  17 IRKKKssdyPKNFH--TWKIAYADFMTALMSFFLLMWITHSIDDKTKISIESYFNpfk 72
gi 754136473  11 IKKGRh--qAHEEHSSAWKLAFADLMVSLMCVFLVLWALQIADKKEKEDIIHYFRTgq 66
gi 643385376  14 CKKCK----CEEGGGSAWEVAYGDFMTSMMAFFLVMWLIAATNVKQRKVLSTYFTQPg 67
gi 644971968  10 KKKCKk---SKPPESSVWEIAYGDFMTSMMAFFLVMWLVAATNEKQRKIIEYYFTHPM 64
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