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cd14869: uS7_Bacteria 
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Bacterial homolog of Ribosomal Protein S7
uS7, also known as Ribosomal protein (RP)S7, is an important part of the translation process which is universally present in the small subunit of prokaryotic and eukaryotic ribosomes. Prokaryotic RPS7 is lacking the variable N-terminal region of eukaryotic RPS7. The ribosome small subunit is one of the two subunits of ribosome organelles that use mRNA as a template for protein synthesis in a process called translation. The small subunits of bacteria and eukaryotes have the same shape of head, body, platform, beak, and shoulder. RPS7 is located at the head of the small subunit which is a primary ribosomal RNA (rRNA) binding protein that assists in rRNA folding and the binding of other proteins during small subunit assembly in all species. RPS7 is also involved in the formation of the mRNA exit channel at the interface of the large and small subunits. Some ribosomal proteins have extra ribosomal functions in cell differentiation and apoptosis.
Statistics
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PSSM-Id: 271248
View PSSM: cd14869
Aligned: 114 rows
Threshold Bit Score: 163.388
Threshold Setting Gi: 12545448
Created: 26-Nov-2013
Updated: 11-Jun-2014
Structure
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Program:
Drawing:
Aligned Rows:
Hierarchy
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Display:
 
Conserved site includes 21 residues -Click on image for an interactive view with Cn3D
Feature 1:rRNA binding site [nucleic acid binding site]
Evidence:
  • Comment:Ribosomal protein S7 directly interacts with rRNA during the assembly of small ribosomal subunit.
  • Structure:1FJG; Thermus thermophilus RPS7 binds 16S ribosomal RNA, contacts at 4A
    View structure with Cn3D
  • Comment:Ribosomal protein S7 plays a critical role in controlling rRNA folding.

cd14869 is part of a hierarchy of related CD models.
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cd14869 is a member of the superfamily cl00313.
cd00323:uS7cd14867:uS7_Eukaryotecd14868:uS7_Mitochondria_Fungicd14869:uS7_Bacteriacd14870:uS7_Mitochondria_Mammaliancd14871:uS7_Chloroplastcd15484:uS7_plant212639684938372351HUS A4937456721351006133991125454482463820349113653032130955955114168960941921339881710708718423361350899226540847527231222417945825004171154435752241780974245138391736782130245731538056053450137729639926045454092340807051149170392607806783GTY S2069011725177930904975353026226110551308300116624206550672923491630672495998788710838071FKA G1RSS A1N32 G1IBL G1FJG G1X18 F4JI7 G4K0K G1HR0 G406994526406965312406956701406993107519100698519101057516989667406929661406959192406994793406927311406882285307069696514031609246382014847598692537956123362424881736761751662848260941943504258094957969623393201045190956142189607874069861294067080214069356036831671551124354496352116494656686548261671494490342261415667912006633837677313247504783815057521072694551156560425243784069120243924044201339942209613622622626617367764345415445290579015165755514068997214070104165511703914068859704068745485190988923201604103837613694957514775187444673000882005723468949518382154619489140697209173067151806115314828497050143582388608538425199331245144472463819840699821140691753018948508118725182960941953914924212639684938372351HUS A4937456721351006133991125454482463820349113653032130955955114168960941921339881710708718423361350899226540847527231222417945825004171154435752241780974245138391736782130245731538056053450137729639926045454092340807051149170392607806783GTY S2069011725177930904975353026226110551308300116624206550672923491630672495998788710838071FKA G1RSS A1N32 G1IBL G1FJG G1X18 F4JI7 G4K0K G1HR0 G406994526406965312406956701406993107519100698519101057516989667406929661406959192406994793406927311406882285307069696514031609246382014847598692537956123362424881736761751662848260941943504258094957969623393201045190956142189607874069861294067080214069356036831671551124354496352116494656686548261671494490342261415667912006633837677313247504783815057521072694551156560425243784069120243924044201339942209613622622626617367764345415445290579015165755514068997214070104165511703914068859704068745485190988923201604103837613694957514775187444673000882005723468949518382154619489140697209173067151806115314828497050143582388608538425199331245144472463819840699821140691753018948508118725182960941953914924
cd14869 Sequence Cluster
cd14869 Sequence Cluster
Sub-family Hierarchy
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 cd14869 Branch
 Whole Hierarchy
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CD Hierarchy
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                        ###   #####  ##                                    #    #   #   
1FKA_G        12 LQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQek---tgQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVP 88
1FJG_G        12 LQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQek---tgQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVP 88
gi 34541544   11 ILPDPVYGDVRVTKFVNHLMYDGKKNTAFSIFYGALDIVKtkhsneeKSALEIWKAALDNITPQVEVKSRRIGGATFQVP 90
gi 133991     12 ISQDPIYNSTLASKVINKILLNGKKTLAQYIFYETMKNIQei---ykKDPLDILRKAIKNASPQMETRKRRIGGTIYQVP 88
gi 307069696  12 IKPDIKFNNLEISKFINILMLSGKKNKSEKIIYKALYYIKsk----nKNPIKIFLKAIENCKPLVEIKNKKIGGSNYQIP 87
gi 321309559  12 LPPDPVYQSQIVSKAINMIMWDGKKQLAQKIFYRAMDLVAqk---sgKPPLEVFLDALKNIAPTIELKTRKIGGSNYQVP 88
gi 529057901   5 YQPDPRFKDPLVTRFVNHLMKDGKKTIAYRIFYNCISEIEkt----kKNGLKIWKEALDNVRPHVEVRSRRIGGSNIQVP 80
gi 24638201   12 SCCDPLFEAPEVGRLVNLVMVSGKKTVAARIVYTALAMLSpd----rRRSYELLMQALHNIKPSAEIRTRRMGGASYRVP 87
gi 484759869   6 SSSDSLWQNEVIRKLTNRLMYSGKKSVAEKLVFQAMSQIQgr---tsKNALEVTLDAIEMIKPYVEVRSIRVAGATYAVP 82
gi 253795612  11 RVPDADASCAVVSKLTNCVMMRGEKRVAARLVYKALAHIQav---vgVGALKTLFEAVDNVTPYMEVRSVKVGGVSYQIP 87
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
Feature 1             ##  #   #      #     ##  #                              
1FKA_G        89 MEVSpRRQQSLALRWLVQAANQrperRAAVRIAHELMDAAEGkGGAVKKKEDVERMAEANR 149
1FJG_G        89 MEVSpRRQQSLALRWLVQAANQrperRAAVRIAHELMDAAEGkGGAVKKKEDVERMAEANR 149
gi 34541544   91 TEIRpERKESISMKNLILYARKrggkTMADKLAAEIVDAFNNqGAAFKRKEDMHRMAEANR 151
gi 133991     89 VEVKeDRGTSLALKFIIEKARErkgrGISTKLKNEIIDASNNtGEAVKKKEEIHKTAEANK 149
gi 307069696  88 VEVNlNRRISLSMKWIKKFALKrkerFTYIKIANELIDASENkGSSINKKIEIYKMAESNK 148
gi 321309559  89 VEASpERKETLSLRWLVMFSRRrtekTIVEALACEIMDAYNNtGLSIKKRNETIKTAESNK 149
gi 529057901  81 TQIPsYVKVTKAMKLLISCARErnekNMYKKLAEEILLASKKeGAAFKKRENIHKMAEANK 141
gi 24638201   88 AEICsKRRMSLALRWLKSAAMRrrerYAHVRLYNEILDALSRrGGAVRQRDEVHRLAHANR 148
gi 484759869  83 VEIReERRLSLALRWLVENSRKrkerEMSQKLAGEILDTYLKtSGSLKKKEELHKMAESNR 143
gi 253795612  88 IDVApKRRLGLAIRWIVAAARRrreaPMWAKLAGELVDSALGrSEACRKREAVRQLVDANQ 148

Citing CDD
Marchler-Bauer A et al. (2013), "CDD: conserved domains and protein three-dimensional structure.", Nucleic Acids Res. 41(D1):D384-52.
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Conserved site includes 21 residues -Click on image for an interactive view with Cn3D