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cl15674: IPT Superfamily 
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Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor receptors), as well as, cyclodextrin glycosyltransferase and similar enzymes. Although they are involved in DNA binding in transcription factors, their function in other proteins is unknown. In these transcription factors, IPTs form homo- or heterodimers with the exception of the nuclear factor of activated Tcells (NFAT) transcription factors which are mainly monomers.
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Taxonomy: root
PubMed: 24 links
Book:
Protein: Related Protein
Related Structure
Statistics
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Accession: cl15674
PSSM Id: 265755
Name: IPT
Created: 7-Nov-2011
Updated: 16-Jan-2014
Superfamily
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Curated CD Hierarchy
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cd00102:IPTcd00602:IPT_TFcd00603:IPT_PCSRcd00604:IPT_CGTDcd01175:IPT_COEcd01176:IPT_RBP-Jkappacd01177:IPT_NFkappaBcd01178:IPT_NFATcd01179:IPT_plexin_repeat2cd01180:IPT_plexin_repeat1cd01181:IPT_plexin_repeat3
CD Hierarchy
Imported CD
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Citing CDD
Marchler-Bauer A et al. (2013), "CDD: conserved domains and protein three-dimensional structure.", Nucleic Acids Res. 41(D1):D384-52.
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