Conserved Protein Domain Family
DUF4349
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pfam14257: DUF4349 (this model, PSSM-Id:258443 is obsolete and has been replaced by 464117)
Domain of unknown function (DUF4349)
This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 282 and 353 amino acids in length. There is a single completely conserved residue D that may be functionally important.
Links
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Statistics
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PSSM-Id: 258443
Aligned: 99 rows
Threshold Bit Score: 126.184
Created: 30-Mar-2013
Updated: 4-Apr-2013
Structure
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Aligned Rows:
Download Cn3D
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q0YS71        17 VSGCGSGKQE-A-------PGSGPAP------AAQv----------------vSS-----------E------------- 42  Chlorobium ferr...
Q2NCQ6        16 LTACSEQVDYeEa-----tVDAADYV------EAEaaadam-------eaaseEA-----------Aa------------ 54  Erythrobacter l...
Q0AMR9        15 LAGCENGSYDeA-------ESGDRMYaitdevTVTgsrqard-----gfmasaPP-----------Pa------------ 59  Maricaulis mari...
Q0C615        15 LAACGSPNRDfS-------APAAPPPv----eMAMkqsaqd-------ydmaaEE-----------Sa------------ 53  Hyphomonas nept...
YP_003059208  14 LSACGGSDEKaSgamnmeySEADFAP------AAMvqasedmmerkmaspspvPV-----------Pt------------ 64  Hirschia baltic...
YP_004086989  21 VSACSKPAEEmT-------TTEDAAP------TAAep---------------dtT-----------Ps------------ 49  Asticcacaulis e...
ZP_00952978   19 sggasteyaireaapepappppaarM------RASadeitv-------sgsrvQR-----------Pd------------ 62  Oceanicaulis al...
YP_001563315  27 laGCNQRHDTaA-------LESAPAP------APMaggagm-------kqgraATvqaedaaaaapEt------------ 74  Delftia acidovo...
ZP_01864213   16 LASCSDGKTYeE-------TEAVATM------DIAepayap-------arssgED-----------Amaelapvappppp 64  Erythrobacter s...
YP_003067653  24 LAGCSDSGR-----------EADGAM------RMAqapap---------------------------------------- 46  Methylobacteriu...

Q0YS71        43 ---------------R------QLAVES---------------RKIIK--EG--VIT--FQ--T--GSLQETRTKIDAAL 76  Chlorobium ferr...
Q2NCQ6        55 --------------gSaipslaELPVSL---------------PKLAYlyDY--RWR--MP--A--DEIGPLQRRHANLC 97  Erythrobacter l...
Q0AMR9        60 --------------pP------PPPSVDmaqspdtpqiddvvqRLIAY--SF--NYQ--LE--TpsDATSGLIDRHREAC 111 Maricaulis mari...
Q0C615        54 --------------gG------EQPAAQ---------------QYIAY--THsiGMR--LP--V--SSIEPTMQGHIAAC 90  Hyphomonas nept...
YP_003059208  65 --------------dG------ATASTG---------------PMLAY--TH--NRS--IEspA--KDVERVVTSHQKMC 101 Hirschia baltic...
YP_004086989  50 --------------qR------VDPASV---------------PQLTYdyRF--DLS--AP--D--KTVSGMMEGHREAC 86  Asticcacaulis e...
ZP_00952978   63 --------------gA------TEAAQG---------------PLLAY--TYqtSLE--LP--A--DILGGAHAAHVEAC 99  Oceanicaulis al...
YP_001563315  75 --------------sA------QDEMAQ---------------RFLAV--RQ--ELN--VE--VpqAQLADAWGQVRDLC 111 Delftia acidovo...
ZP_01864213   65 gsgqtrtetippsasS------PVTVAM---------------PQVAY--TY--AYG--FR--VppDLIRPMQEKHADMC 115 Erythrobacter s...
YP_003067653  47 ----------apfvsA------AREGST---------------AKLAY--RH--DLTvgLG--P--DRVAPHFAAARDRC 87  Methylobacteriu...

Q0YS71        77 --RASDGF---MAK--ES-E--NRy----sDKVEQKVEVRVPAEK--------FDSFV----RKV-----Te----G--- 118 Chlorobium ferr...
Q2NCQ6        98 --EQQGPA---SCQ--ILgM--SKsge-eaDEVYGELQMAVASRQ--------ARAFG----ALL-----Ede-aeD--- 146 Erythrobacter l...
Q0AMR9       112 --LAAGPG---TCQ--VI-S--ANvye-qgNGVAGSLALRALPVW--------IESFR----DGL-----LdevdaA--- 160 Maricaulis mari...
Q0C615        91 --NAAGPS---VCI--ITnS--WLtay-aeDSVGASLNLRATPAW--------IETFL----SGV-----EaeaeaA--- 140 Hyphomonas nept...
YP_003059208 102 --EKAGFQkcmVVN--SN-Q--NGig---eEWASANLHIRATPEW--------ITEFF----QDLpkdlkK-----T--- 151 Hirschia baltic...
YP_004086989  87 --TVAGLT---ICQvlSL-S--SQnt--gkDGQFHTLTLRATPQW--------IGLFRknlnNEL-----K-----A--- 135 Asticcacaulis e...
ZP_00952978  100 --QNAGPA---TCQ--VI-R--AQvnnadgPRPSAYLQLRAAPDW--------IVEFR----AGL-----E-----Teae 147 Oceanicaulis al...
YP_001563315 112 --ATLRCE---LLS--AS-L--LRet--pqQPGNAMLEMRVAPAD--------VQRLL----GTL-----A-----G--- 154 Delftia acidovo...
ZP_01864213  116 --EAKGPQ---VCR--IV-SmnSGes--egDYAYGSLQIAIASGE--------ARTFG----KAL-----T-----A--- 160 Erythrobacter s...
YP_003067653  88 ldAAATCT---LLN--SS-I--RDgn--gaSPPQAQIEVRLPHAAvaayvafvTGPLP----GEA-----A-----G--- 140 Methylobacteriu...

Q0YS71       119 --V-----E-G-FDEKNISITDVTKEFIDVEARLKVKKETEQRYRELL-G-K-AG---K-IEDILAIEKQIGELRSEIES 182 Chlorobium ferr...
Q2NCQ6       147 --A-----GaE-QVSAEIGSQELSKQMVDTEARIAARTELRDRLMAVL-KtR-RG---T-VEELVEAERSVARVNEEIDQ 212 Erythrobacter l...
Q0AMR9       161 --D-----G-R-IRHQSQSAEDLTATIYDMEARLEAKRTLRTRLTALL-E-R-PGa--S-VEEMVQVERELARVQGDIEG 225 Maricaulis mari...
Q0C615       141 --K-----G-D-VTNRQTTAEDLTVSIIDTGARLKAQKTLQERLQALLaE-R-PG---E-LGDLLETERELARVNGEIDS 205 Hyphomonas nept...
YP_003059208 152 --D-----S-K-ITSASTSAQDLSTQIVDTDARLKAQLTLRDRLQALLtD-R-PS---E-LGDLIELERELSRVQSDIDA 216 Hirschia baltic...
YP_004086989 136 --T-----G-AaIESQSIATEDLSLSLIDTEAHIKNQTALRDNLQATL-R-ShKG---K-MNEVIELKQQLATIQSDIDS 201 Asticcacaulis e...
ZP_00952978  148 elG-----G-Q-VLSDQTSVEDLTTRIVDTAARVQAQTTLRDRLQQLL-EtR-DG---D-LSDLLAVERELANVQADLDA 214 Oceanicaulis al...
YP_001563315 155 --V-----A-T-IVSQNTISEDKTAEVIDVEARIRNRTEFRDSLRLML-R-D-TTtkrT-MSDLLEIQRTLSDTQAELDA 221 Delftia acidovo...
ZP_01864213  161 --TtegmkG-E-LVSSSIQGEDLSKRIVDTEARLRARTVLRDRLMEVL-RnR-KG---T-VAELVEAERGVAQVNEEIDQ 230 Erythrobacter s...
YP_003067653 141 --D-----V-V-LIEQATRAEDLTASIADTGRRLAQLNDYRTRLTALA-E-K-PD---NrAEDLIKIAGELAQVQSQIEE 205 Methylobacteriu...

Q0YS71       183 VEGRLLYLRDAVALSSLTITFYEN---ISAPATFLSDFGVGFKNGWNNLVqf-------iVIMVNAWPFFIIIPIVV-IM 251 Chlorobium ferr...
Q2NCQ6       213 ARSWLKEMEGRVAYSRVTVRYETg---VPVTNDFLAPVAGAVGSLGTVLGyl-------vAFLILAGAVALPIGGLV-WA 281 Erythrobacter l...
Q0AMR9       226 SEAQIRAMRGRVSMSSLTLNYTSRv--DPVSRSAFDPLNRALRNLTGNFArglanmltflAGFLPWLIVIVPAGWILtRW 303 Maricaulis mari...
Q0C615       206 LTSSLATLRQRVDMSQLAVNYETKl--NPVSQGALQPLGEAFGNFFYNLAsaia---avvTAFAVGLPWLLLIGALL-WI 279 Hyphomonas nept...
YP_003059208 217 NASILAALRQRVAMSNLHMNYSAKstvTS--RSVWAPLADAFGNFFKNFAgalgavvtaiAVIIPWLPVIGGLLWFG-RW 293 Hirschia baltic...
YP_004086989 202 AQTAVATMKKRVAMSKLTLTYRPa--sAVAVDGTWAPLKSALSDVGPNMIsvltvmvavaGYL---LPLGLIAAPVV-WW 275 Asticcacaulis e...
ZP_00952978  215 QASVLAALRQRVDTSLLTLNYQAEr--QVVEPETFNPIGRAFKEMGDVFAesvaslilflAGALPWLVIAVPVISGV-II 291 Oceanicaulis al...
YP_001563315 222 MTAQRKVLEQQTSKQHIQIQFTPTralVQGGTSY-SPIGRALRDAGHVLGesmaalitfvAAvlpwlvlvllplgwvlra 300 Delftia acidovo...
ZP_01864213  231 ARSWLTQMRGRVAYSTMTLEYea---gTPTEGGFLDPIRGAWGSLAAIFGnliallmllvTVVLP-------MGLLV-WG 299 Erythrobacter s...
YP_003067653 206 AEGTRRGLDERVDTEIVTVDFRT----SRARAGAFAPVQEVWARSGPILGesaasalrftVASLPWLPIVLFAALLL-RL 280 Methylobacteriu...

Q0YS71       252 IRR 254 Chlorobium ferrooxidans DSM 13031
Q2NCQ6       282 GRS 284 Erythrobacter litoralis HTCC2594
Q0AMR9       304 LGG 306 Maricaulis maris MCS10
Q0C615       280 WLR 282 Hyphomonas neptunium ATCC 15444
YP_003059208 294 IYR 296 Hirschia baltica ATCC 49814
YP_004086989 276 ARH 278 Asticcacaulis excentricus CB 48
ZP_00952978  292 GFR 294 Oceanicaulis alexandrii HTCC2633
YP_001563315 301 lwr 303 Delftia acidovorans SPH-1
ZP_01864213  300 AVR 302 Erythrobacter sp. SD-21
YP_003067653 281 VWR 283 Methylobacterium extorquens DM4
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