pfam04050: Upf2 (this model, PSSM-Id:252337 is obsolete and has been replaced by 461146)
Up-frameshift suppressor 2
Transcripts harbouring premature signals for translation termination are recognized and rapidly degraded by eukaryotic cells through a pathway known as nonsense-mediated mRNA decay. In Saccharomyces cerevisiae, three trans-acting factors (Upf1 to Upf3) are required for nonsense-mediated mRNA decay.