Conserved Protein Domain Family
PRK
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cd02026: PRK 
Phosphoribulokinase (PRK) is an enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. This enzyme catalyzes the phosphorylation of D-ribulose 5-phosphate to form D-ribulose 1, 5-biphosphate, using ATP and NADPH produced by the primary reactions of photosynthesis.
Links
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Statistics
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PSSM-Id: 238984
Aligned: 29 rows
Threshold Bit Score: 318.513
Created: 20-Oct-2004
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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Active site
Feature 1:Active site [active site]
Evidence:
  • Comment:GxxxxGK[S/T], signature p-loop motif, also known as Walker A motif, present in various triphosphate nucleotide binding proteins. The Lys residue within the motif plays a major role in the phosphoryl transfer.
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1            #    ####                                                                  
XP_467296    59 VIGLAADSGCGKSTFMRRLtsvfggaaeppkggnpdsntlisdtTTVICLDDYHslDRTGRkekgvTALDPraNDFDLMY 138 Oryza sativa (ja...
NP_488163    10 LIGVAGDSGCGKSTFLRRLidlf-----------------geefMTVICLDDYHslDRKQRketgiTALDPraNNFDLMY 72  Nostoc sp. PCC 7120
ZP_00161135  10 LIGVAGDSGCGKSTFLRRLidlf-----------------geefMTVICLDDYHslDRKQRketgiTALDPraNNFDLMY 72  Anabaena variabi...
ZP_00109191  10 LIGVAGDSGCGKSTFLRRLidlf-----------------gedlMTVICLDDYHslDRKQRketgiTALDPraNNFDLMY 72  Nostoc punctifor...
P37101       10 LIGVAGDSGCGKSTFLRRLtdlf-----------------geefMTVICLDDYHslDRQGRkaagvTALDPraNNFDLMY 72  Synechocystis sp...
NP_441778    10 LIGVAGDSGCGKSTFLRRLtdlf-----------------geefMTVICLDDYHslDRQGRkaagvTALDPraNNFDLMY 72  Synechocystis sp...
NP_925242    10 LIGVGGDSGCGKSTFLRRLkdlf-----------------skelVTVICLDDYHslDRKQRketgiTALDPraNNFDLMA 72  Gloeobacter viol...
AAP79209    140 IFGVAADSGCGKSTFLRRVnaifgttts-------kahtptgdlITTICLDDFHtlDRTGRadtgiSALDVraNNFALMA 212 Bigelowiella natans
NP_486390     7 ILGIVGDSAAGKTTLTRGIaqvl-----------------gpenVTLICTDDYHryDRQQRaeigiTALHPdcNHLDIMQ 69  Nostoc sp. PCC 7120
NP_925068    35 IVGVAGDSGSGKTTYSNGIrrll-----------------gsdlVSTLCTDGYHkeDREQRqisgrLPLDPaaNHLDRLA 97  Gloeobacter viol...

Feature 1                                                                                       
XP_467296   139 eqvkaIKEGKAIEKPIYNHvtGLLDPPeliqPPKIFVIEGlhpmfdervrdllDFSIYLDIsdevkfaWKIQRDMAERGH 218 Oryza sativa (ja...
NP_488163    73 eqikaLKEGQTINKPIYNHetGLIDPPeivkPNHIVVVEGlhplydervrsllDFSVYFDIsdevkiaWKIQRDMAERGH 152 Nostoc sp. PCC 7120
ZP_00161135  73 eqikaLKEGQTINKPIYNHetGLIDPPeivkPNHIVVVEGlhplydervrsllDFSVYFDIsdevkiaWKIQRDMAERGH 152 Anabaena variabi...
ZP_00109191  73 eqiktLKSGQAIDKPIYNHetGLIDPPervePNHIIVVEGlhplydervrsliDFSVYFDIsdevkiaWKIQRDMAERGH 152 Nostoc punctifor...
P37101       73 eqiktLKSGQSIMKPIYNHetGLLDPPekvePNKVVVIEGlhplydervrelvDFGVYLDIseevkinWKIQRDMAERGH 152 Synechocystis sp...
NP_441778    73 eqiktLKSGQSIMKPIYNHetGLLDPPekvePNKVVVIEGlhplydervrelvDFGVYLDIseevkinWKIQRDMAERGH 152 Synechocystis sp...
NP_925242    73 eqataLKVGQSIMKPIYNHetGKIDPPeliePTPIVILEGlhpfydarvrnlfDFKIYFDLsdpikiqWKIQRDMAERGH 152 Gloeobacter viol...
AAP79209    213 dqlkaLKQGRAIKKPIYNHdtGAIDPVetihPNHIIIVEGlhpmldkdvieslDFTFYIDVsdpvkkaWKIERDMVERGH 292 Bigelowiella natans
NP_486390    70 qhlslLRTGQPILKPVYSHktGSFEPPqyikPNKFVIIEGllgystraardcyDVKVYLAPpenlrakWKVKRDTQKRGY 149 Nostoc sp. PCC 7120
NP_925068    98 ehlkaLKQGKAVPIPVYNHgsGKFEQPenfvPTPIVVVEGlhtlyp-elipylDFSLYVDPdhpvkwqWKWERDLKRRGH 176 Gloeobacter viol...

Feature 1                                                                                       
XP_467296   219 slesikasieaRKPDFDAFIDPQKqyaDAVIEVlPTQLIPDDnegkvlrvkl--imkegvknfnPVYLFDEGSSIt-WVP 295 Oryza sativa (ja...
NP_488163   153 ryedvlaainsRKPDFQKYIEPQRefaDVVLQVlPTNLIKDDterkvlrvrm--lqregkegfePAYLFDEGSTIn-WTP 229 Nostoc sp. PCC 7120
ZP_00161135 153 ryedvlaainsRKPDFQKYIEPQRefaDVVLQVlPTNLIKDDtdrkvlrvrm--lqregkegfePAYLFDEGSTIn-WTP 229 Anabaena variabi...
ZP_00109191 153 ryedvlaqinsRKPDFEKFIEPQRefaDVVLQVlPTNLIKNDterrvlrvrm--lqregkegfdPTYLFDEGSTIn-WTP 229 Nostoc punctifor...
P37101      153 tyedilasinaRKPDFTAYIEPQKqyaDVVIQVlPTRLIEDKeskllrvrlv---qkegvkffePAYLFDEGSTId-WRP 228 Synechocystis sp...
NP_441778   153 tyedilasinaRKPDFTAYIEPQKqyaDVVIQVlPTRLIEDKeskllrvrlv---qkegvkffePAYLFDEGSTId-WRP 228 Synechocystis sp...
NP_925242   153 tyedvlkqiesRRPDFSAYIDPQKqyaDVVLQIlPSELPEKAggikrvkacm--vqvdgipnydAPYLFDRAISDvcWKP 230 Gloeobacter viol...
AAP79209    293 kkediiasiesRKPDFEKFVEPQKanaDVIISIePTKLDVAPgeetkylntrliqrenqhgirpVYMFEEEGSTVd-WDP 371 Bigelowiella natans
NP_486390   150 tpeqvlaelekREPDSEQFIRPQRqwsDIVVSFyPPHEDGDEtnghlnvrlvl-rptiphpdftSIINLTNGSSVs-AIR 227 Nostoc sp. PCC 7120
NP_925068   177 kaeqleqemlqREAAFKRWIDFQKidaNVVIKIfHSQLQCLAphqftgil-------pnpcykvELILQPAPVPLp-TLP 248 Gloeobacter viol...

Feature 1                                                                
XP_467296   296 CGrkl----tcsYPGIKFAYGPdtyfghevsvleMDGQFDRldelIYVESHLSNLST 348 Oryza sativa (japonica cultivar-group)
NP_488163   230 CGrkl----tcsYPGMQLYYGSdvyygryvsvleVDGQFDNleevIYIETHLSNTST 282 Nostoc sp. PCC 7120
ZP_00161135 230 CGrkl----tcsYPGMQLYYGSdvyygryvsvleVDGQFDNleevIYIETHLSNTST 282 Anabaena variabilis ATCC 29413
ZP_00109191 230 CGrkl----tcsYPGMQLYYGSdvyygryvsvleVDGQFDNleevIYIETHLSNTST 282 Nostoc punctiforme PCC 73102
P37101      229 CGrkl----tctYPGIKMYYGPdnfmgnevslleVDGRFENleemVYVENHLSKTGT 281 Synechocystis sp. PCC 6803
NP_441778   229 CGrkl----tctYPGIKMYYGPdnfmgnevslleVDGRFENleemVYVENHLSKTGT 281 Synechocystis sp. PCC 6803
NP_925242   231 NFpn-------sDEELTFCYGTqdyfgrpasylsIDGEFAPed-sPELEEKLRNTSE 279 Gloeobacter violaceus PCC 7421
AAP79209    372 CAgpga--macpYPGTRVRYYNemsgekhahvleVDGVFGEteelFFIEERLSNTNT 426 Bigelowiella natans
NP_486390   228 LGldr----dmsKPVDVLEVDGhat-------leQVNKLEHi--lCSDMPYLSSVCD 271 Nostoc sp. PCC 7120
NP_925068   249 LPfdlaamlavdQPPFMLAAVPyrywgrsaiaihLDGVLSQkt-iAGLEDYIVNYTG 304 Gloeobacter violaceus PCC 7421

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