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COG0834: HisJ 
ABC-type amino acid transport/signal transduction systems, periplasmic component/domain [Amino acid transport and metabolism / Signal transduction mechanisms]
Statistics
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PSSM-Id: 223904
View PSSM: COG0834
Aligned: 269 rows
Threshold Bit Score: 38.4453
Threshold Setting Gi: 19553331
Created: 7-Oct-2002
Updated: 16-Jan-2013
Structure
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Aligned Rows:

COG0834 is classified as a model that may span more than one domain.
COG0834 is not assigned to any domain superfamily.
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20092710   63 MLQGLSVDLLEEITEKMGKKVtreevhlvpwtegyqAALNgnntvlfsmarspereqffkwagpiysdryvlfakrdrGI 142
gi 15889505    1 -------------------------------------------------------------------------------M 1
gi 15600330    1 ---MLKVLIQTLILGVLLGAS----------------------------------------------------------A 19
gi 15600331    1 ---MQRSLLFALLATLLLVG-----------------------------------------------------------G 18
gi 15600332    1 ----MSIFRLALGCVGSLALL----------------------------------------------------------C 18
gi 16764977      --------------------------------------------------------------------------------
gi 15643926      --------------------------------------------------------------------------------
gi 15641606      --------------------------------------------------------------------------------
gi 7467522     6 GTGQEPIGIEHDFASGIAKELginieykgfdtiealLNAVstgkadmaigf-----------------gqtlaregkfLF 68
gi 16330443      --------------------------------------------------------------------------------
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20092710  143 TIKNpeDLKGYRIGVIADDIATRQLLDIGVnqsqiapesnvsaiiaglengdidlwacpedagryfteeltgsyysytvv 222
gi 15889505    2 KPMEaaMGLIRFCLLFLALATPVNAAKLFLt------------------------------------------------- 32
gi 15600330   20 ARAE--LPADYKVVLLTENFPPFNMAVDDKn------------------------------------------------- 48
gi 15600331   19 ARAE--TDPDYSMVLLTENFPPYNMAINGKn------------------------------------------------- 47
gi 15600332   19 ASAL--ARAET-LVLLTENLVPFNMAVNGGn------------------------------------------------- 46
gi 16764977    1 MLSKkfGLSMIVLGIMSSSAFADSIVEGRTlnvavspas--------------------------------------ppm 42
gi 15643926      --------------------------------------------------------------------------------
gi 15641606      --------------------------------------------------------------------------------
gi 7467522    69 SKPLyeNVRVIWLRDKAMEEKPFASLKWVCiqgtsyceilkdrgypniimarnysssvemirqgiadatvtnyvslnhyl 148
gi 16330443      --------------------------------------------------------------------------------
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20092710  223 yqletqDLYYAFSKDVPDSVVQSFQQALdavkrekdvegistydrilgkyipsiglarlnylteEWAPFNYQEDGNVTGI 302
gi 15889505   33 -----tEVYPPYNLQASDGSVHGVYFDQlk--------------------------------ivLQDTDTDYEVAVMPWA 75
gi 15600330   49 -----fARDDGIDGISADIVREMFRRAGi-----------------------------------GYSLSLRFPWDRLYRL 88
gi 15600331   48 -----fAQEDNIDGIAVDIVREMFKRAGi-----------------------------------KYSLTLRFPWDRIYKL 87
gi 15600332   47 -----yAKDDGISGISTDTVRAACERAQi-----------------------------------ECQLILRFPWDRVYQQ 86
gi 16764977   43 lfksadGKLQGIDLELFSSYCQSRHCKLn--------------------------------------ITEYAWDGMLGAV 84
gi 15643926    1 --------MIGIRGIVLLFLILSISIFSqplr-----------------------------ialDEDYAPFSFYDENGNL 43
gi 15641606    1 -----mTVRSQLTHDSKTSLDHQGTVMLsng------------------------------ylkRYVRCCLLIIGLCPAL 45
gi 7467522   149 sqkrlaLGKVIFDPDLGVQTNRILINNNepl------------------------------llsAINKVIDADKQGLTEN 198
gi 16330443    1 -----------------------------------------------------------------MLILRRLILVVSLSF 15
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20092710  303 SVEILEAVFKNigvnrsradvrivplaegfqiaqnntstvlFSIVRtPEREPFYKwAGPFTRANFVLYAPVSSNITissp 382
gi 15889505   76 RAIALATTQAMh----------------------------cVFATArTPEREKLFkWVAPIHTDRNILVARREANIea-- 125
gi 15600330   89 TLDKPGYGLFS------------------------------MTYTP-ERVPQFKW-VGPLADTSWVLLAPAGSKIA---- 132
gi 15600331   88 ALEKPGYGVFV------------------------------TARLA-EREDKFKW-VGPIGPDDWVLLAKGDSPIT---- 131
gi 15600332   87 ALSEPGYGVFS------------------------------TARTP-EREDKFKW-VGPLAVNDWVLMARGDSSIH---- 130
gi 16764977   85 ASGQADVAFSG------------------------------ISITD-KRKKVIDF-SEPYYINSFYLVSMANHKIT---- 128
gi 15643926   44 VGISVDFWKLFsekt-----------------------gveVELVPvKWYRSQELlTEKKIDAIDQIFKTPEREKVlsfs 100
gi 15641606   46 LYAQSSPNAEDk----------------------------lVRIASgEWPPFIGSdLPNYGFVGEIITQAFTKQGYqvef 97
gi 7467522   199 KLNSADVYFLNdq--------------------------anLNILRnENVNPVVRyTIQDDLFPMSYWDEKEKKYKgyvh 252
gi 16330443   16 ATIAIDITTRPg-----------------------------LEPVQgQGVETVDSqTLKVGVVGNPPFVFYGEGK----- 61
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20092710  383 kdlnqyrigairasiendllasqgvnesqiingqtpedlfrmleegqidLWATGDLAGrhqmlrtaedpNAYEIVYTLSe 462
gi 15889505  126 --------------------------------------------------sSLEDARR-----------YRVGTQRGDY- 143
gi 15600330  133 -------------------------------------------------VKNLKDAAR-----------YKLGAYKNDA- 151
gi 15600331  132 -------------------------------------------------LGSLDEAKK-----------YRIGAYKGDA- 150
gi 15600332  131 -------------------------------------------------LNSLEDAAR-----------YRIGGYKNDA- 149
gi 16764977  129 -------------------------------------------------LNNLNELNK-----------YSIGYPRGMAy 148
gi 15643926  101 rpifemr--------------------------------scvffrkdlpIKDFSDLSS-----------YVVGALRGEG- 136
gi 15641606   98 q--------------------------------------------flpwARAYAETQRgl--------yDATAIWMHSAe 125
gi 7467522   253 dlleristksilkfefvp----------aygrdvedmlrhgkvdlipsfNMTYVDDRYfih------tgRYTDIQFGYIe 316
gi 16330443   62 ----------------------------------------------------NAAFTG-----------ISLDVWRAVAe 78
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20092710  463 nd--fyYIFSKDVPDTLVSAFQQALDTVrdqrdeqgvsdyeRIIYRNLGVGCAPQTFTDDTVMELVntTVKAIEKNASDT 540
gi 15889505  144 ---------TEALLEKLGFPQVDVGADF-------------EITLNKLKLGRIDLMPMSESTLKS----LPANSFKEVIT 197
gi 15600330  152 --------VSQHLEAQGIPVINALRDQE---------------NVKKLTGGQIDLWATTDPVGRY----LAKQEGVSGLQ 204
gi 15600331  151 --------IAEFLGKNGFEADLALRDQE---------------NAQKLVKGQIDLWASGDPAGRY----LAKQEGVTGLK 203
gi 15600332  150 --------ISQHLVDRGLQVQLALRDNE---------------NVDKLASGQIDLWVTADPSGRY----VAQREGLKEVK 202
gi 16764977  149 s---dlIKNDLEPKGYYSLSKVKLYPTY-------------NETMADLKNGNLDLAFIEEPVYFT-----FKNKKKMPIE 207
gi 15643926  137 --------SVKTLLEKNPDVEFEFFDDY-------------SSIVKALKEKKISVFLGDDIATRY----YLSKGNLLPEF 191
gi 15641606  126 r---eiDFFYSLPVSQEEFVFFYPVKKPfdwktlsdlapykLGGVLAYSYGKELDALLDSGVLTMErdGLAAKNLEKLAK 202
gi 7467522   317 ttrpytTPITGILDRTGKFNAYIAVQKNlsdvk---vyrsmYDLEQALEKGDITHGLLNKVLINQMllDGHQDAFKLSPL 393
gi 16330443   79 --------SQKWN------SEYVRQNSI-------------SAGITAVAEGELDILIGPISVTPER-------------- 117
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 20092710  541 FRRINAGeapyR---------DSKDPGLYAFvyDtNlTIVAHADNIQLVGTNFRGkt---dVTGKPFRDEILEGALKNGT 608
gi 15889505  198 LSRQQLG----------------LACNKTVP------DQIIAKLQARLDKLIADG------TQQQIFDRYSLVSP----- 244
gi 15600330  205 TVLRFNE--------------AKLYLALNKDt---P-DEVVERLQKALEQMRQEG------FVDEAVANYL--------- 251
gi 15600331  204 TVLRFNS--------------DQLYLALNREt---P-DEVVQKLQAALDGMRKEG------FVEDILNSYL--------- 250
gi 15600332  203 VVQRFHT--------------AELFLALNKDt---P-DELVQKLQTAVDALRSEG------LLKQIRERY---------- 248
gi 16764977  208 SRYVFKN----V---------DQLGIAFKKG------SPVRDDFNLWLKEQGPQK-------ISGIVDSWMK-------- 253
gi 15643926  192 RTLHLETn--------------YLHVAVLKGn-----ESVLSLINSGLSRISEGE-------KNDIIRNYVPLVLvtppw 245
gi 15641606  203 GRVDLVPeekhI---------GYYLINQQIPhlQdLiTHHPTPFLTNSNYLLFPKqsarsqELLGVFNHYLVQTQKKKKK 273
gi 7467522   394 TEGQDLRadmtMlvrkdarglQNMLQKVLATfsQqEiDEIKGAYDRVTVYFGYDKqkvliyALIILCALLSIGLILTLSL 473
gi 16330443  118 --------------------------AAIEG------ITFTQPYFSSGIGLLIPG------KPVSLWERFSpffgiaals 159

                 ...
gi 20092710  609 GSV 611
gi 15889505      ---
gi 15600330      ---
gi 15600331      ---
gi 15600332      ---
gi 16764977      ---
gi 15643926  246 flr 248
gi 15641606  274 Q-- 274
gi 7467522   474 SRL 476
gi 16330443  160 sag 162
Citing CDD
Marchler-Bauer A et al. (2013), "CDD: conserved domains and protein three-dimensional structure.", Nucleic Acids Res. 41(D1):D384-52.
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