15601518 5 THSSHARKALLSERINKLAKALSDG-VYE-------------RENTIKLCLLTALAGESVFLLGPPGIAKSLIAKRLIQA 70 Vibrio cholerae 14601056 1 -MRLNPERPLLSGSCTQYLDWGLPIaMDA-------------VGPGEARRILDRYGADRVLLVGPPGVGKSTVVRSYAED 66 Aeropyrum pernix 15895133 7 LEGIKLVLESKAVPLLVGESGIGKTsLVKkl----------sKDEEYYYINIDGNLLKEGEIGGLPVVQDYGDEKSLIKK 76 Clostridium acetob... 15806190 1 -------------------MTLTPQ-----------------ELQTYLAALVRQNLQIATMIWGPPGVGKSSVVAQVARQ 44 Deinococcus radiod... 20093916 19 QVTIEDDWIIFEGEEGFVRLPKDPYkVIEdfeeygyffdeehRRDFAAMYMTLIVEQTPVLLVGPPGTGKTKLVRLIGEL 98 Methanopyrus kandl... 18311706 1 ----MAFSVRVTEIPLEDRLFLIGPpGIGk------------TEVVMQKAEEEAARMGRLFVNLREEIPPDLFQRPEKYY 64 Pyrobaculum aeroph... 15926989 1 --------MALKHYKNS-DSTVFN------------------DAKALFD------LNKNILLKGPTGSGKTKLAETLSEV 47 Staphylococcus aur... 15643692 1 ---------------------------MR-------------VEEAKYLAKKIMMAGEIPLLVGHFGVGKTDIARDIARE 40 Thermotoga maritima 16082881 7 QQEEHLPEAIVCKWCGKSFHYLKSHiSMGrce--------niPESAKGLDVDEVVKMYTSAFPDEPTISRTALVKLNEKR 78 Yersinia pestis 15606998 596 vghfppwvgrylkhlnglcsaeqyrvpefvsfeetpwfvqnlerftslvkeqlqyhegiLILEGDAGVGKNFLVEVFSAL 675 Aquifex aeolicus
15601518 71 FDn----SSYFEYLMTRFSTPEEVFGPLSIQELKDN---------------------GRYVRLTQGYLPTAQ-------- 117 Vibrio cholerae 14601056 67 SAsr-egLEFVDLSEARSLEDLDTDSTYAFLHIYAPlvraedlafiarrgegydwtlPSRLAYLTRPGVRG--------- 136 Aeropyrum pernix 15895133 77 TVya-ayYKFIKIDEILKNNPNQKVLLFIDEINRCEh--------------------SVQQEIMNIILNREIn------- 128 Clostridium acetob... 15806190 45 HD-----LDFVDVRLS-QLAPTDLRGLPVPEADAQG---------------------SGVSRWYPPEFLPRAga------ 91 Deinococcus radiod... 20093916 99 YD-----VPVVVMRGHQEAREQEFIGGVDVAALPVAdkiaeeytevgnmeyeeaieaLKEFIYVGGYLKDVVndarrrga 173 Methanopyrus kandl... 18311706 65 VFl---rVVAPHVFPEDLGLPKHADGYAEFLP-------------------------PKALKAMTLKGIAG--------- 107 Pyrobaculum aeroph... 15926989 48 VD-----TPMHQVNCSVDLDTESLLGFKTIKTna---------------------egQQEIVFVDGPVIKAMke-----g 96 Staphylococcus aur... 15643692 41 TE------RKLIILVLSQMEPGDLIGLPARTEEK-----------------------TVFLKPDWWPESGDt-------- 83 Thermotoga maritima 16082881 79 AErhsgeGKVAEISAHPGYAGTVEYKTELVAAHELLgvtikelg-----tprgkplqVTVNVNTPYPEFVPEakk---ny 150 Yersinia pestis 15606998 676 TN-----RPLFIIPCNSKMEKEDITFIYEFDPK------------------------KGTKKVYSDLVRALRtp-----g 721 Aquifex aeolicus
15601518 118 -VVFLDEIWKAG-PAILNTLLTVVNEKTFKNGSDI-------------ERVPMRLLVTAS-N-------ELPDEDSG--L 172 Vibrio cholerae 14601056 137 -LVFIDEITNVAlPEVQTILFSMVLDKRVAYNRLS-----------------SGVEVVAAgNs------PRDSPVSQwpP 192 Aeropyrum pernix 15895133 129 gYKLKDNITVIA-AMNPSSKYDEFEESDYQVNDMDpa---------qeDRFVWIYLESDVnNwie--wgHERINGESriH 196 Clostridium acetob... 15806190 92 gILFLDEVNMAP-PTMQGMAQQLILDRRVGSYELP-----------------DGWFVWAAgNr------KEDRASVFdmP 147 Deinococcus radiod... 20093916 174 cLFFIDEVNRFPgYMIPTLIHIFEKDTEVIYIPHSpi----------dFGETGAIMRIGAlN-------P-EGKGTTnfD 235 Methanopyrus kandl... 18311706 108 -VLFIDELSNVQ-RDDQIAMYYSLILEKEAGWMLR---------------ISDGVKIIAAgNp------PEWSEVARpiP 164 Pyrobaculum aeroph... 15926989 97 hILYIDEINMAK-PETLPVLNGVLDY-RRQITNPYtg---------evIKAVPGFNVIAAiN-------EGYVGTLPm-N 157 Staphylococcus aur... 15643692 84 -ILFLDEINRAH-RSVRNAIMQLLVDRRIHNHILPegtwimaamnppeEEYDQADLITDPaFisrffilEVNPDVSEwlE 161 Thermotoga maritima 16082881 151 vYGDFDLIKDIF-MMLEIGIPGYLWGHAGTGKSSLptq--------lcALLNRPLIRAQHtAsmeeahvTGQILARDgsT 221 Yersinia pestis 15606998 722 aVIYLDEINTLP-PSLVKIFNPLFDYRRYLVLSYGe-----------vVKARPDVILVGGmN-------PQNYLGVSelP 782 Aquifex aeolicus
15601518 173 EALYDRML-------VRIFVNRIQNKQ-NFKSMLTVG--TAQE---AQIPAGLAITDEEYHQWQQQLD------KLELSD 233 Vibrio cholerae 14601056 193 PPLLDRFR-------LLIRVKPP-DLEeWVSWMNSVGrpWDRRv-aAVLKVKPVLMYRPPEDEEDKFPtp--rsWSQLAW 261 Aeropyrum pernix 15895133 197 EDILGFIAs------FPEYLSTPNSKEsIKATPRSWErvSNi----YKAYIKKKTKVSRNIFYNLIRGn----vGTSIAQ 262 Clostridium acetob... 15806190 148 APLANRFLhltvrpdFDSWRSYALAKGlHEHVIAFLTfrPELLw--RLDPQQPAWPSPRSWEMAAQLHragldaSSAIGE 225 Deinococcus radiod... 20093916 236 EALLRRVE-------LVPWGEYDVEIYkRIAIESARQiiE------LTKMAEEVLEDLASLIKDMGKG-------VDVAK 295 Methanopyrus kandl... 18311706 165 KPLRNRLT-------IINVAPPTVEEWtAYMQRRYGDgwERLAalhLAVYPEDFLSPPPEDSSPFPTPr-----SWTSLA 232 Pyrobaculum aeroph... 15926989 158 EALKNRF--------VVIHVDYIDGDIlKNVIKEQSLlqD-------DKQIEQIIKFNEDLRTMSKQ-------GQISEE 215 Staphylococcus aur... 15643692 162 WAEKNNVSke----vRDFIRDYPEFLFsERSLSLRTSlkPSPRswyKLSNVLKTLTDDEKEKYGYVIAa-----GIVGPE 232 Thermotoga maritima 16082881 222 YFEPGLLA-------LAMKNGWVYLADeYDFAFPQILgvYQPVlegEPLIIKEATPDWRRITPHKRFAfigtgnTNGSGD 294 Yersinia pestis 15606998 783 QDIKSRA--------DIMYVDYPPFEDeKGFYYPDEAliLKDYldtLASLNKEEFTYLWYYVVNDVKTq----lGEKLRT 850 Aquifex aeolicus
15601518 234 DVFEKLYQLKTMVEERSKesa---gsdLEMYVSDRRWKKAAKLLKASAFFNGRDEINPLDLLLLQNCLWNTPESHDVVHE 310 Vibrio cholerae 14601056 262 ELAKTGAHGDEAVRIAAMvv------gRRAAEEARQFLQPDPASLDLSTFPRLDERERLTLLSVEAGRLASQDVVELCRT 335 Aeropyrum pernix 15895133 263 DFINYIDESKSPLLTPEDifa---ndcISEDIKDRIRKESHSRLFLSAKNILFYLENKEDRSREVEIFSEFLSLYPNDLK 339 Clostridium acetob... 15806190 226 AAGAEFAAFVRLFEQLPDlgtv-lsgaGAGLKLPDEPSVRYAAVVGLAARAADAEEAYRAFTWLADSAGPEWLQLYVATL 304 Deinococcus radiod... 20093916 296 DVAQTVAIGIKMGYDVDT---------VARNVANKILGDMLLDSEKAEEFEARRNALERKIKEKLKPVFKS--------- 357 Methanopyrus kandl... 18311706 233 VLLHKHKNASDGLKEALAvgnlgeevgARFAALLRTNLNIKEALRKLEKSPSYFDKLTVNQRLLLLDAVAQQPLDRLAGP 312 Pyrobaculum aeroph... 15926989 216 AASIR-ALLDLCDLITV---------------MPVERAIKRTIIDKLEDER-EQQAIYNAVELNF--------------- 263 Staphylococcus aur... 15643692 233 AAKAFYDSFFQRVKIPSVesvlfdgkiENLEDIHAANTLVLRIVDFLSKVDVRTLERHLDDVSKNLVRLSEIMPKESFYG 312 Thermotoga maritima 16082881 295 ETGLYQGTNIQNAANFSRfgi----vsNVKYMSTKAEVNMLAEAGVIREYAEKMVKFANLVREGYEQHLISQPIGPRELL 370 Yersinia pestis 15606998 851 PERERDVKLLFDLLKIAN-----------EIRKAYRAYQTQQSEEPVEFVFSIRDTIRCARRLRKYGDAKTVVMETIIPK 919 Aquifex aeolicus
15601518 311 VIRefalrya-fdqaevEQQLDVCRLELAQIQEEL 344 Vibrio cholerae 14601056 336 LEKvgsygahyavwllmLSGVDTVEAARSCSYVED 370 Aeropyrum pernix 15895133 340 LGImqn--------iksDSSKKLYKEFLENTSFLE 366 Clostridium acetobutylicum 15806190 305 VSKfqalgqlgelagllGRDPRLAELVQGALSLAE 339 Deinococcus radiodurans 20093916 ----------------------------------- Methanopyrus kandleri AV19 18311706 313 LKGflehlsrehremlvLVTLLMDREKRVALMKKL 347 Pyrobaculum aerophilum 15926989 ----------------------------------- Staphylococcus aureus subsp. aureus N315 15643692 313 VLRflvdeaq-kegeksWIFDKILEKMLEREDMRK 346 Thermotoga maritima 16082881 371 LSAkigmmrgdfsagieKSFINKLPSTSAQAAREV 405 Yersinia pestis 15606998 920 ISS--------------PLEKEIVKSIIERAVG-- 938 Aquifex aeolicus
Jiyao W et al.(2023). "The conserved domain database in 2023.",