pfam00781: DAGK_cat (this model, PSSM-Id:216116 is obsolete and has been replaced by 425868)
Diacylglycerol kinase catalytic domain
Diacylglycerol (DAG) is a second messenger that acts as a protein kinase C activator. The catalytic domain is assumed from the finding of bacterial homologues. YegS is the Escherichia coli protein in this family whose crystal structure reveals an active site in the inter-domain cleft formed by four conserved sequence motifs, revealing a novel metal-binding site. The residues of this site are conserved across the family.