NCBI CDD Logo
?
pfam10034: Dpy19 
Q-cell neuroblast polarisation
Dyp-19, formerly known as DUF2211, is a transmembrane domain family that is required to orient the neuroblast cells, QR and QL accurately on the anterior-posterior axis: QL and QR are born in the same anterior-posterior position, but polarise and migrate left-right asymmetrically, QL migrating towards the posterior and QR migrating towards the anterior. It is also required, with unc-40, to express mab-5 correctly in the Q cell descendants. The Dpy-19 protein derives from the C. elegans DUMPY mutant.
Statistics
?
PSSM-Id: 150680
View PSSM: pfam10034
Aligned: 12 rows
Threshold Bit Score: -1
Threshold Setting Gi: 0
Created: 22-Dec-2011
Updated: 5-Jan-2012
Structure
?
Aligned Rows:

pfam10034 is not assigned to any domain superfamily.
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74777060    46 TVLSSIIFSSFLILRHRK---MLLRSYEEQKMSLFSETAFYFSFYDDIVnSSESIYNIIKKMISDDRTEYPDIINSLSRF 122
gi 74948677    16 GCGFFFLYVQHVRVIFETrtnIQQLNQLEREALLRREDALYYAFYKQLA-EGPDFWHGYEQLKNVTDIEYPHSVNVLQRF 94
gi 224487912   38 GLFVGFLNYQHIYTLFENdkhFSHLADFEREMAYRTEMGLYYSYYKTII-TAPSFLEGVQLITRDTVTEHGHQINTLNRF 116
gi 82273710     1 AVVSGFLHWYHLTHLFENdrhFSHLSTLEKEMAFRTEMGLYYSYYKTII-EAPSFMGGLHEVMNDGLTEYPLVINTLKRF 79
gi 82085462    70 AVVAGFFHWYHLSHLFENdrhFSHMSTLEKEMAFRTEMGLYYSYFKTII-EAPSFMDGLYMIMNDRLTEYPLVINTLKRF 148
gi 121941680   27 AVFAAVLHWSHITHLFENdrhFSHLSTLEREMAFRTEMGLYYSYFKTIV-EAPSFLNGVWMIMNDKLTEYPLVINTLKRF 105
gi 162416266  113 AVFVAILHWLHLVTLFENdrhFSHLSSLEREMTFRTEMGLYYSYFKTII-EAPSFLEGLWMIMNDRLTEYPLIINAIKRF 191
gi 74713335    59 AVTSGMMYALYLSAYHERkfwFSNRQELEREITFQGDSAIYYSYYKDML-KAPSFERGVYELTHNNKTVSLKTINAVQQM 137
gi 74710923    54 ALCIGLLTSVYLATLHENdlwFSNIKEVEREISFRTECGLYYSYYKQML-QAPTLVQGFHGLIYDNKTESMKTINLLQRM 132
gi 156360896   60 ACTFGFLNSWHVSRMFENerfFSHLSALERELSFRTEMGLYYSYYKTMV-EAPTFLDGLHAVMNCNVTEYPDTVNTLKRF 138
gi 156386782   51 ACYVGYKYALYVKELHENdmwFSNIGQVEREISFRTESGLYFSYYKQLV-LAPSITKGLYDLSHDNTTEHLRTINILERF 129
gi 156094942   12 SLLVCLFAAL---TFYKRfryTFYRNYEEQKLSLYSEESFYFSFFDDIV-KSETYLEGLKLLLRDDRSEYPNTINAIRRF 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74777060   123 NIYQEVILGILYKLFLEFYFKL-------------------------Kfiihliysfingehllkntfgfnnlssefvfl 177
gi 74948677    95 YVLPELVTAYFFHVVRSGFNPM-------------------------V-------------------------------- 117
gi 224487912  117 NLYPEVILAFLYRPFRALAKSA-------------------------Nwqvetcwqvnrg---------dlrpvescegi 162
gi 82273710    80 NLYPEVVLASWYRTYTGVMAYL-------------------------Giptktcwsvnrge--------gltpvdscegl 126
gi 82085462   149 NLYPEVVLASWYRAYSSTMNFF-------------------------Gfptklcwtinrge--------gldpvescegl 195
gi 121941680  106 NLYPEVILASWYRIYTKIMDLI-------------------------Giqtkicwtvtrge--------glspiescegl 152
gi 162416266  192 HLYPEVIIASWYCTFMGIMNLF-------------------------Gletktcwnvtrie--------plnevqscegl 238
gi 74713335   138 SLYPELIASILYQATG-SNEII---------------------------------------------------------- 158
gi 74710923   133 NIYQEVFLSILYRVLP-IQKYL---------------------------------------------------------- 153
gi 156360896  139 NLYPEVILAGKFRIFEWLASKFeyqtktcytvnrgyglppvqsceglG-------------------------------- 186
gi 156386782  130 NIYQEVILAVLYRTIPGIQES--------------------------V-------------------------------- 151
gi 156094942   88 NIYPEVVLGTVWRVFNLKESFL---------------------------------------------------------- 109
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74777060   178 sTPYNFYFFFVNSLLGIGMGVLCGTSTFIAdGSYISGLTCMGFLFanFRLRLLSRIS-SLPLRENFALPFIWINNMILIS 256
gi 74948677   118 -QPMQFYLEFVWLMGGVTLLVLYLYGTLLS-ENIFGGIYGVISYL--MFHSFVAKIYeRPLARENFAFPFIFLQMFYLCI 193
gi 224487912  163 gNPHYFYITGVFVVAGTVATSLFYLGVLVS-DSIFGGILSVLCFA--FNHGEATRVQwTPPLRESFAFPFIIGHIAILTY 239
gi 82273710   127 gDPAYFYVACVFLLNGVMMSLFFLFGFYLS-NSNLGGIVTTACFF--FNHGESTRVMwTPPLRESFAYPFLVLQMLLLTY 203
gi 82085462   196 gDPAYFYVAFVFLLNGAMMSLFFIYGTYLS-GSRLGGTVTVLCFF--FNHGESTRVMwTPPLRESFSYPFLVLQMLLLTY 272
gi 121941680  153 gDPACFYVAVIFILNGLMMALFFIYGTYLS-GSRLGGLVTVLCFF--FNHGECTRVMwTPPLRESFSYPFLVLQMLLVTH 229
gi 162416266  239 gDPACFYVGVIFILNGLMMGLFFMYGAYLS-GTQLGGLITVLCFF--FNHGEATRVMwTPPLRESFSYPFLVLQMCILTL 315
gi 74713335   159 -EPVYFYIGIVFGLQGIYVTALFVTSWLMS-GTWLAGMLTVAWFV--INRVDTTRIEySIPLRENWALPYFACQIAALTG 234
gi 74710923   154 -EPVYFYIYTLFGLQAIYVTALYITSWLLS-GTWLSGLLAAFWYV--TNRIDTTRVEfTIPLRENWALPFFAIQIAAITY 229
gi 156360896  187 -ELSFFYVYSIFFLTGLMMACFFILCFYLS-GSILGGVLGTLCYF--FNHGEATRVMwTPPLRESFSYPYLVAQLLVVTF 262
gi 156386782  152 -EYVYFYINSVFALHALYIVALYCSAWILS-GSWLAGLLAACFYI--FNKDDTTRIVyTIPLRESFGFPFLFTQMAFITY 227
gi 156094942  110 -TPFNFYVYA-------------------G-RSYISGAIFLMLFFscYREKFIMRLS-AFPLRENFASVYMWCNILLIYA 167
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74777060   257 IIKYt-nRGNQKKKWILLYFTSVI---LLEFWQFSVFVISTQILSVYALFLFGCEHSKlilVLRKLIFFNM-------IA 325
gi 74948677   194 CIGRiihRQRHTSRMFMIFAMSLFtacALLSWQFSTFIFTTQILIMMTSWNASALPTA---LVNAFVLDYS-------LS 263
gi 224487912  240 IIKY---RKSSTAHLLLLISAAVP---ALLFWQFTQFAFFTQICSIFAAFSMDLVPLD---TAKTIIKSHL-------SA 303
gi 82273710   204 ILRK---PNPSRAAMVALGVSNLC---FMLPWQFAQFVLLTQVASLFASYVLGYLAAT---KMQSILVTHMvelpllqVT 274
gi 82085462   273 ILRT---KNPSKNTMMALGISNVF---FMLPWQFAQFVLLTQVASLFASYILGYLSPA---KMQSILVTHM-------VS 336
gi 121941680  230 ILRA---TKLYRGSLIALCISNVF---FMLPWQFAQFVLLTQIASLFAVYVVGYIDIC---KLRKIIYIHM-------IS 293
gi 162416266  316 ILRT---SSNDRRPFIALCLSNVA---FMLPWQFAQFILFTQIASLFPMYVVGYIEPS---KFQKIIYMNM-------IS 379
gi 74713335   235 YLKSnlnTYGERFCYLLMSASTYT---FMMMWEYSHYLLFLQAISLFLLDTFSVEQSD---KVYEVYKIYI-------FS 301
gi 74710923   230 FLRPnlqPLSERLTLLAIFISTFL---FSLTWQFNQFMMLMQALVLFTLDSLDMLPAV---KATWLYGIQI-------TS 296
gi 156360896  263 TLRS---VKVTWRHITLVSMTTAL---FMIPWQFAQFALLTQTCALFVVYIMHFITAD---KFCKILYGLL-------VA 326
gi 156386782  228 FLKRdigRLAQVACVLGIALNSFF---FTLVWQFAQFILLLQCFAFFGVYSLGFTPKH---KVKILYVVVI-------GS 294
gi 156094942  168 ILRE---RK------------------------FSVFVTLTHVVALFGLDLLGFDIQK---ELRSILLTFS-------CS 210
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74777060   326 MFTSYLLHF----FNYYILLTPLPQIGVSILLSISL------------------------CKILF--K--REKFSLLYSF 373
gi 74948677   264 HLLGHALAFvmshGNSQLLLTWQLSISLFLFLITMVrqlr-----------------hvrSRRLG--HaqDLLNGDLFSL 324
gi 224487912  304 FFISFVMLF----GNEMMIAALYFPSIWALATVIYIsp--------------------mlAGIRL-----RPLYLLILAL 354
gi 82273710   275 LAVCFVLMF----GNSMLLTSFYASSLVSIWAIVALrd--------------------rfCQAFR--P--GVVRWVMQVL 326
gi 82085462   337 LAVCFLLMF----GNSMLLTSFYASSLVSIWGVIALrd--------------------rlVGTFR--P--GLITWVTQCF 388
gi 121941680  294 LALCFVLMF----GNSMLLTSYYASSLVIIWGILAMkp--------------------hfLKINV--S--ELSLWVIQGC 345
gi 162416266  380 VTLSFILMF----GNSMYLSSYYSSSLLMTWAIILKrn--------------------eiQKLGV--S--KLNFWLIQGS 431
gi 74713335   302 LFLGYLLQF----ENPALLVSPLLSLVAALMLAKCLqln-------------------vkKGSFV--A--KIIK-VINFY 353
gi 74710923   297 LLLVCILQF----FNSMILGSLLISFNLSVFIARKLqkn-------------------lkTGSFL--N--RLGKLLLHLF 349
gi 156360896  327 HLLNFAVQF----GNSMLLSSFFMSAVISALVVAKAes--------------------qiHKLPY--Q---LLIWATQGL 377
gi 156386782  295 LLLVCAMMF----GNDMMLCSLALSFSVAALVIMGVqkep-----------------yapNPTLL--I--RLVKLVLNIV 349
gi 156094942  211 YVASLVATF----FPRYLMCTYLPFVLAAIITTNAIyrrgggstsggrgkpapnqrdgapCTLPLqfP--HFRSRVMFVL 284
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74777060   374 TSGIISLALFLVFKLILn----------pFSDHDTHVFDMLkSAIFGQEFANFDTMIYKMgGSEFSFITKEQLEMIKNSG 443
gi 74948677   325 KFLMLTLLLASSVQTTLielfnragvvsvTEGDQQHFFDIC-AHWALQVNVGFVAHLSAC-NPQYARVAWSELWQLVKTM 402
gi 224487912  355 IFGSITLGLKVGFSKGL------------GIEDDAHIFDILrSKF--TSFANFHTRLYTC-SAEFDFIQYATIEKLSSTL 419
gi 82273710   327 VWVVSTVLLKFMLSTVL------------CASDDAHISALIkSKF--MSYRDFHTLMYTC-AAEFDFLELET-------- 383
gi 82085462   389 AWVVSTVILKFMLSVIF------------GASDDAHISSLIkSKF--TSYKDFDTMMYTC-AAEFDFIEADTPIRYIKTM 453
gi 121941680  346 FWLFGTVILKYLTSKIF------------GIADDAHIGNLLtSKF--FSYKDFDTLLYTC-AAEFDFMEKETPLRYTKTL 410
gi 162416266  432 AWWCGTIILKFLTSKIL------------GVSDHIRLSDLIaARI--LRYTDFDTLIYTC-APEFDFMEKATPLRYTKTL 496
gi 74713335   354 LVCTLTITLNIIMKMFV------------PHKENGHMLKFLeVKFGLNMTKNFTMNWLLC-QESLQAPSQDFFLRLTQSS 420
gi 74710923   350 MVLCLTLFLNNIIKKIL------------NLKSDEHIFKFLkAKFGLGATRDFDANLYLC-EEAFGLLPFNTFGRLSDTL 416
gi 156360896  378 GFAAGTLGIKVAVAKVL------------SIADD--------SKF--TSYRDFHTLLYTC-APEFDFLDQEAPVKLTKTL 434
gi 156386782  350 LVLFLMFALTALIKTIL------------NVESDEHIFKFVkAKLGYDIGRDFDSLLYLC-EPAFQMLPRETYQRLTSGI 416
gi 156094942  285 KKGVTSIVIFLLLRLTTl----------gMEKDDSHVLSLLkVRLHLGSH-NFDSMIYSV-GSEFNPFTRHMFGMIRETS 352
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74777060   444 VLFIFIPGTFLIL-------------FSIIIDTaniraskyfpykniessfsyqfedcsqindei-----------sdss 499
gi 74948677   403 IVKPYCMYGVVMLamffrrwrksgapVSALTEEqrerarkyvledfieehfvsmsdmssketekqlykcfrllkscdydy 482
gi 224487912  420 LIPLALLSIGAFS------------------------------------------------------------------- 432
gi 82273710   384 -----------------------------GQDV----------------------------------------------- 387
gi 82085462   454 LLPINVLIVAFIA-------------GRIIQDV----------------------------------------------- 473
gi 121941680  411 LLPVVLVVFVAIV-------------RKIISDM----------------------------------------------- 430
gi 162416266  497 LLPVVMVITCFIF-------------KKTVRDI----------------------------------------------- 516
gi 74713335   421 LLPFYILVLIICF-------------LSMLQVI----------------------------------------------- 440
gi 74710923   417 LFYAYIFVLSITV-------------IVAFVVA----------------------------------------------- 436
gi 156360896  435 LLPSAIVAASAVI-------------AKVGASE----------------------------------------------- 454
gi 156386782  417 VFPCYVPLIPS--------------------------------------------------------------------- 427
gi 156094942  353 LFDYFVFFSVILL-------------ICAANWV----------------------------------------------- 372
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74777060   500 snssivstaasyspeaaislkqsnvhcfKNNLQDEYPKNLKEKqssyknkknllldkfyNINFENQDTA----------- 568
gi 74948677   483 erykraqaslrkeqpparddfmqdikrlRAQINRNSVKQRKERaqetkeaatdgastptEEEDKDPEAEseskkknqepg 562
gi 224487912  433 ----------------------------WDFLSKTSLLWRT------------------LENEDSEYGE----------- 455
gi 82273710   388 ----------------------------VRFLKEGGRDGAAQGraatrlprrvktvcwcECVCELLSPQ----------- 428
gi 82085462   474 ----------------------------IVFLRNEKQEKSEDDe--------------tEQSHLLAKGV----------- 500
gi 121941680  431 ----------------------------WGVLAKQQTH---------------------VRKHQFDHGE----------- 450
gi 162416266  517 ----------------------------SYVLATNIY----------------------LRKQLLEHSE----------- 535
gi 74713335   441 ----------------------------FRRINGKSLKETVTL----------------EDGRIGERPE----------- 465
gi 74710923   437 ----------------------------FHNLSDSTNQQSVGKm---------------EKGTVDLKPE----------- 462
gi 156360896  455 ----------------------------WEYWVRGKKSQVKSDsadehd-----egaqgQEANPRPHAE----------- 490
gi 156386782  428 ----------------------------PSRISNPH-----------------------HMTILNEQPE----------- 445
gi 156094942  373 -----------------------------------------AG----------------GDHLEAFEAH----------- 384
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74777060   569 ---------------------------------------------------------------------ISFLTFQTIFF 579
gi 74948677   563 sgetetesaadptetppsrsadneeeeeehsataagcgsnssghrqrkrsssrrssvvptanaqilnmhYVYSFLQMLVF 642
gi 224487912  456 ---------------------------------------------------------------------VIYNLVQLICS 466
gi 82273710   429 ---------------------------------------------------------------------LVYHSLQLLAF 439
gi 82085462   501 ---------------------------------------------------------------------LVYHSLQLVAF 511
gi 121941680  451 ---------------------------------------------------------------------LVYHALQLLAY 461
gi 162416266  536 ---------------------------------------------------------------------LAFHTLQLLVF 546
gi 74713335   466 ---------------------------------------------------------------------IIYHVIHTILL 476
gi 74710923   463 ---------------------------------------------------------------------TAYNLIHTILF 473
gi 156360896  491 ---------------------------------------------------------------------YVYHVLQAMAF 501
gi 156386782  446 ---------------------------------------------------------------------LVYCTIQTVLY 456
gi 156094942  385 ---------------------------------------------------------------------FLYVVIQFICF 395
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74777060   580 CLLAIIISRLRVLALPYIAVVSS-L-FASRKYlsfifnyykpillwifrikynknkainpnkryfNNrIACFIFFATSII 657
gi 74948677   643 TLIGLAVRKLFFLSFTQGCVIAP-T-VCSKLW---------------------------------YHrQRNIFWSVSLAV 687
gi 224487912  467 TTMAVLIMRLKLFMTPHLCITVA-L-LANSKLlggd-------------------------------kiakTVRSSVLVG 513
gi 82273710   440 AILAILIMRLKLFLTPHMCIMAS-L-ICSKQVqlaaarisafalwev-------------grsyldglgtnlntgRAVFL 504
gi 82085462   512 AVLAVLIMRLKLFLTPHMCIMSC-L-ICSRQLfgwige--------------------------------klklqMTVVG 557
gi 121941680  462 TALGILIMRLKLFLTPHMCVMAS-L-ICSRQLfgwlfc--------------------------------kvhpgAIVFA 507
gi 162416266  547 TALAILIMRLKMFLTPHMCVMAS-L-ICSRQLfgwlfr--------------------------------rvrfeKVIFG 592
gi 74713335   477 GSLAMVIEGLKYIWIPYVCMLAA-FgVCSPELwmtlfkw-------------------lrlrtvhPIlLALILSMAVPTI 536
gi 74710923   474 GFLALSTMRMKYLWTSHMCVFAS-FgLCSPEIwelllk----------------------svhlyNPkRICIMRYSVPIL 530
gi 156360896  502 VLMAVIIMRLKLFGTPALCVLAS-L-VASRQFfsflgd--------------------------------rrrhqAIVIA 547
gi 156386782  457 GAMAVTTLRFKFLWTPHMCVFGAgT-LCHQGFwrfvl------------------------eragIH-K----------- 499
gi 156094942  396 ALLALMISRLRVLALPLMCLLSS-L-VGSPHLlgdvyrvtr---------------qnlrlgpgkKG-LSRLVIQAICLL 457
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74777060   658 FLSFSISK-FPFSEIQTGLIPENNASSSkSRLVGWINSNLPNHTPILSDMVVSATLRLATKTKIVTHPQYEHIKIRRRTQ 736
gi 74948677   688 FLLSMFDPgMVNIREEYFPTRYSKSGDDlDSMLEWIKLNTERDAVFAGPVDIIGTVHLTTKRPIVNHAHLEMRQIAERTE 767
gi 224487912  514 LVAMLAFRgIPNIRHQLNIKGEYSNPDQ-EMLFDWIQSNTKQDAVFAGTMPVMANVKLTTLRPIVNHPHYEHVGIRDRTL 592
gi 82273710   505 LLALMAVQgVANLQAQWAIIGEFSNLPQ-EELLDWILENTQPNAVFAGAMPTMASVKLSTGRPIVNHPHYEDAGLRERTK 583
gi 82085462   558 ILCIMAAQgVVNLQSQWSIIGEFSNYPQ-EELLEWIKDSTSPTAVFAGAMPTMASVKLSTGRAIVNHPHYEDAGLRARTK 636
gi 121941680  508 ILAAMSIQgSANLQTQWNIVGEFSNLPQ-EELIEWIKYSTKPDAVFAGAMPTMASVKLSALRPIVNHPHYEDAGLRARTK 586
gi 162416266  593 ILTVMSIQgYANLRNQWSIIGEFNNLPQ-EELLQWIKYSTTSDAVFAGAMPTMASIKLSTLHPIVNHPHYEDADLRARTK 671
gi 74713335   537 IGLSLWKEfFPRLMTELMELQEFYDPDT-VELMTWIKRQAPVAAVFAGSPQLMGAIKLCTGWMVTSLPLYNDDDLLKRNE 615
gi 74710923   531 ILLYLCYKfWPGMMDELSELREFYDPDT-VELMNWINSNTPRKAVFAGSMQLLAGVKLCTGRTLTNHPHYEDSSLRERTR 609
gi 156360896  548 LIAVMSVQgFSNLKTQFNTTGEYNNPEM-EELVEFITTRTQKDAVFAGAMPTMATVKLSTGRAVVNHPHYEDVGIRERTH 626
gi 156386782  500 ----PSVRlKPALE-ELKELREFHDPDT-VELMNWIKTSTPPGSSFTGSMQLLAGVKLCTDRHVTNHPHYENKFLRMRTK 573
gi 156094942  458 ECAYPFAKyFPTYEYLNLAGDDPVNIQKnLDLVVWLRQNLKEGEPIITDIPTSSFLRSTTNFKMVLNPHYENVAMRRRVQ 537
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74777060   737 FMYSISACISLKELYE-TMqQQYKTEYLLLSIYRCAIpRGDKnaitMIHVTNFLDNINHRCNNQen---------ifQRT 806
gi 74948677   768 HVYSVYSRQQSSDIYN-QC-AQLKIQYLIISLDECTN-EVRD----DCDLLAIWDDKQPAYQKY-------------PQF 827
gi 224487912  593 KVYSMFSKKPVAEVHQ-TM-KKMGVNYFIFQLMNCSNdERRP----ECVYRGMWDEEDPKNSAR-------------TSL 653
gi 82273710   584 LVYSMYSRMSGETVKR-NL-MKLGVDFFVLEDSWCTR-RTRP----GCSMPEIWDVEDPQNAGK-------------LPL 643
gi 82085462   637 MVYAMYSRKPAEEVKR-NL-IKLQADYFILEDSWCTR-RSKP----GCSMPEIWDVEDAENAGK-------------VPL 696
gi 121941680  587 IVYSMYSRKAAEEVKR-EL-IKLKVNYYILEESWCVR-RSKP----GCSMPEIWDVEDPANAGK-------------TPL 646
gi 162416266  672 IVYSTYSRKSAKEVRD-KL-LELHVNYYVLEEAWCVV-RTKP----GCSMLEIWDVEDPSNAAN-------------PPL 731
gi 74713335   616 NIYQIYSKRSAEDIYK-IL-TSYKANYLIVEDAICNEvGPMR----GCRVKDLLDIANGHMVCEegdkl---tyskyGRF 686
gi 74710923   610 AVYQIYAKRAPEEVHA-LL-RSFGTDYVILEDSICYErRHRR----GCRLRDLLDIANGHMMDGpgendpdlkpadhPRF 683
gi 156360896  627 KVYQIFSRKPPHVVWN-TL-DSMGVTHVIIDAQWCMG-RPKP----GCGMSDMWDLEDEKNRHR-------------SMC 686
gi 156386782  574 QVYQVYARRTPQEVHE-IL-ITHGANYVILENSICYS-RMRR----GCKLSDILDMDNGHVIEGgqpreg-srdpsvPRF 645
gi 156094942  538 DYYMFSSCLPFSDAKRyYY-DRYKVRYFVANIYRCAS-TSSQvt-nAFNVAEFVGSNYARCRHKt-----------sMKF 603
                         970       980       990
                  ....*....|....*....|....*....|....*....
gi 74777060   807 CWR--IQLDsqS---R------YFDLVYR-NAHYSLYKR 833
gi 74948677   828 CHE--LLHK--N---Vp-----SFLKVFA-NDHYGIIKM 853
gi 224487912  654 CDLwiLAAN--S---KdnsrispFKIVYNpNRNYIVLKI 687
gi 82273710   644 CTH--MSRN--S---Rp-----HFVTVFS-NDVYKVLQV 669
gi 82085462   697 CTL--MSRD--S---Rp-----HFSTVFH-NNIYKVLRV 722
gi 121941680  647 CNL--LVKD--S---Kp-----HFTTVFQ-NSVYKVLEV 672
gi 162416266  732 CSV--LLED--A---Rp-----YFTTVFQ-NSVYRVLKV 757
gi 74713335   687 CHE--VKIN--Y---Spy--vnYFTRVYW-NRSYFVYKI 715
gi 74710923   684 CEE--IKRN--L---Ppy--vaYFTRVFQ-NKTFHVYKL 712
gi 156360896  687 CSQ--LEVD--S---Kp------FVKVFK-NKKYSIYKL 711
gi 156386782  646 CDA--IKRD--DsafRr-----YFRLVFE-NRTFYMYKV 674
gi 156094942  604 CQR--VLYD--D---R------NYKTLYR-NGKFSVIYF 628
Citing CDD
Marchler-Bauer A et al. (2013), "CDD: conserved domains and protein three-dimensional structure.", Nucleic Acids Res. 41(D1):D384-52.
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap