Conserved Protein Domain Family
Rpn3_C

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pfam08375: Rpn3_C 
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Proteasome regulatory subunit C-terminal
This eukaryotic domain is found at the C-terminus of 26S proteasome regulatory subunits such as the non-ATPase Rpn3 subunit which is essential for proteasomal function. It occurs together with the PCI/PINT domain (pfam01399).
Links
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Statistics
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PSSM-Id: 149439
View PSSM: pfam08375
Aligned: 25 rows
Threshold Bit Score: 77.7506
Threshold Setting Gi: 124480447
Created: 29-Mar-2013
Updated: 4-Apr-2013
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

pfam08375 is a member of the superfamily cl07120.
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4B4T_S       450 NIYDSEDPQQVFDERIKFANQLHDEYLVSMRYPEDKKTQQNEKSEnGENDDDTLDGDLMDDMSdisdldD 519
gi 122119934 434 DAYSTQEPLHAFSNRIDICLKIHNDSLKAMRFHPDLNKAETEKIA-EVAKTIKEEMERQAEESsdnegdS 502
gi 124480447 424 DLYGTKAPQEAYGERINNCLGLYNQAVKALQYQNPEYDYGEKQAD-D-------ELTTDELLSlae-ldF 484
gi 74587259  415 DVYSTKLPQAEFDQRIKFCLSLHNESVKSMRYPNDNEKENTNKE--IEPSEEV---ELLKAIEegd-ldD 478
gi 74609506  443 NTYITEDPQTVFDERIRFVNQLHDECVVAMRYPQDKKKGLN---N-QNHDDEYLEGDLLDDLSdfsdidD 508
gi 74695277  433 NVYATMQPQQAFDDRINFVNQLHDECVMAMRYPGSREKKKNVKTD-DH--EGEIDPDIMDLSDygsdieD 499
gi 74606400  436 NVYSTKQPQQVFDERIRFVNHLHSDYVTGMRFPDSREEDNSKKLS-DESLETTMDLNSMNLSDfdsdldD 504
gi 146422890 403 DVYSTKLPQDDFDQRIKFCLSLHNDSVKSMRYPSADNRSDINKHN-LAAKED--EMDLLKAIEegd-ldD 468
gi 149244392 412 DVYSTNLPQAEFDQRIKFCLSLYNDSVKSMRFPDDNENKAITKDA-EPSD----EVELLKAIEegd-ldD 475
gi 190405583 450 NIYDSEDPQQVFDERIKFANQLHDEYLVSMRYPEDKKTQQNEKSEnGENDDDTLDGDLMDDMSdisdldD 519
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