1SF2_A 26 FADRAENCRVWDVEGREYLDFAGGIAVLNTGHLHPKVVAAVEAQLKKLSHTCFQVLAYEPYLELCEIMNQKV----PGdF 101 Escherichia coli P28269 35 LIVAAEGSWLVDDKGRKVYDSLSGLWTCGAGHTRKEIQEAVAKQLSTLDYSPGFQYGHPLSFQLAEKITDLT----PG-N 109 Pseudomonas putida P22805 33 VIKKGEGVWLYDEQNQRYLDAVSSWWVNLFGHANPRISQALSEQAFTLEHTIFANFSHEPAIKLAQKLVALT----PQ-S 107 Lysinibacillus sphaer... P46395 27 LVTKTDGVFLTLEDGSTVIDAMSSWWSAIHGHGHPRLKAAAQKQIDTMSHVMFGGLTHEPAIKLTHKLLNLT----GN-S 101 Corynebacterium gluta... P44426 30 AVERADGVMITLKDGRRLIDGMSSWWAALHGYNHPRLNAAAQNQLAKMSHIMFGGFTHDPAVELAQLLVQIL----PN-G 104 Haemophilus influenzae P30268 28 PVVKEEGCYYYGVDGVKYLDFTSGIAVTNVGHRHPKIVQAIKEAADHLTHGPIGVIQYESILKLADELADIL----PG-D 102 Bacillus pseudofirmus P14010 76 DYTKSVGNYIADLDGNMLLDVYAQIASIPVGYNNPHLLKVAASPEMATSLINRPALGNFPSADWAHILKTGIlkvaPK-G 154 Emericella nidulans P40829 41 FVTRAAGGVIEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRAQVADFTHTCFIITPYEEYVAVTEQLNRIT----PGsG 116 Mycobacterium leprae P80404 76 NYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLlsvaPK-G 154 human P46716 49 FITEARGCWLTDADGRRYVDLVCSWGPMILGHAHPAVVDAVATVAASGLS---FGAPTPAETQLAAEIIGRM-----A-P 119 Mycobacterium leprae
1SF2_A 102 AKKTLLVTTGSEAVENAVKIAR--------AATKRS--------------------GTIAFSGAYHGRTHYTLALtGKVN 153 Escherichia coli P28269 110 LNHVFFTDSGSECALTAVKMVRayw--rlkGQATKT--------------------KMIGRARGYHGVNIAGTSL-GGVN 166 Pseudomonas putida P22805 108 LQKVFFADNGSSAIEVALKMSFqyh--mqtGKTQKK--------------------RFLALTDAYHGETLGALSV-GGVD 164 Lysinibacillus sphaer... P46395 102 FDHVFYSDSGSVSVEVAIKMALqas--kgqGHPERT--------------------KLLTWRSGYHGDTFTAMSVcDPEN 159 Corynebacterium gluta... P44426 105 LDKIFFADSGSVAVEVAMKMAIqyq--hakGEVQRQ--------------------KFATIRSGYHGDTWNAMSVcDPTT 162 Haemophilus influenzae P30268 103 LDCFFFANSGTEAIEGALKLAK--------FVTKRP--------------------YVVSFTGCFHGRTQGSLGVsTSKS 154 Bacillus pseudofirmus P14010 155 LDQVFTAMAGSDANETAYKAAFmyyrqqqrGGPEKEfteeeiqssmlnqtpgspqlSIMSFKAGFHGRLFGSLST-TRSK 233 Emericella nidulans P40829 117 EKRSVLFNSGAEAVENSIKVAR--------SYTRKP--------------------AVVAFDHAYHGRTNLTMALtAKSM 168 Mycobacterium leprae P80404 155 MSQLITMACGSCSNENALKTIFmwyrskerG--QRGfsqeeletcminqapgcpdySILSFMGAFHGRTMGCLAT-THSK 231 human P46716 120 VERIRLVNSGTEATMSAVRLAR--------GFTGRT--------------------KIIKFSGCYHGHVDALLA--DAGS 169 Mycobacterium leprae
1SF2_A 154 PYSAGMGLMPGHv--------YRALYPCPLHg------------ISEDDAIASIHRIFKNDAAPEDi--AAIVIEP-VQG 210 Escherichia coli P28269 167 GNRKLFGQPMQDv--------DHLPHTLLASnays-----rgmpKEGGIALADELLKLIELHDASNi--AAVFVEP-LAG 230 Pseudomonas putida P22805 165 LYNEVYQPLLLDtvraqgpdcFRCPFKHHPD---------------SCHAQCISFVEDQLRMHHKEi--TAVIIEPlIQA 227 Lysinibacillus sphaer... P46395 160 GMHSLWKGTLPEq--------IFAPAPPVRG---------------SSPQAISEYLRSMELLIDETv--SAIIIEPiVQG 214 Corynebacterium gluta... P44426 163 GMHHLFHHSLPVq--------YFLPQPNIPF-------------NESWNDCAIEPLADLLKKKGNEi--AALILEPvVQG 219 Haemophilus influenzae P30268 155 KYRKFLQPN-GLt--------YQVPYFKPSDprildeegevvesLACELLEEEFTNLFKYHVSSEEv--AAVILEP-VLG 222 Bacillus pseudofirmus P14010 234 PIHKLDIPAFDW---------PQAPFPSLKYpleeh----akenAEEEQRCLQEAERLIKEWHNPV---AAIIVEP-IQS 296 Emericella nidulans P40829 169 PYKSGFGPFAPEi--------YRAPLSYPYRdglln----kdlaTDGKLAGARAINVIEKQVGADDl--AAVIIEP-IQG 233 Mycobacterium leprae P80404 232 AIHKIDIPSFDW---------PIAPFPRLKYpleef----vkenQQEEARCLEEVEDLIVKYRKKKktvAGIIVEP-IQS 297 human P46716 170 GVATLSLPSSPGvtgaaaadtIVLPYNDIEA------------------------VRQTFARLGDQi--AAVITEA-SPG 222 Mycobacterium leprae
1SF2_A 211 EGGFYASSPAFMQRLRALCDEHGIMLIADEVQSGAGRTGTLFAMEQMGVAP---DLTTFA-KSIAGG-FPLAGVTGRAEV 285 Escherichia coli P28269 231 SAGVLVPPEGYLKRNREICNQHNILLVFDEVITGFGRTGSMFGADSFGVTP---DLMCIA-KQVTNGaIPMGAVIASTEI 306 Pseudomonas putida P22805 228 AAGMKMYPAIYLRRLRELCTQYDVHLIADEIAVGFGRTGTLFACEQANISP---DFMCLS-KGLTGGyLPLSVVMTTNDV 303 Lysinibacillus sphaer... P46395 215 AGGMRFHDVALIEGVATLCKKHDRFLIVDEIATGFGRTGELFATLSNGLQP---DIMCVG-KALTGGfMSFAATLCTDKV 290 Corynebacterium gluta... P44426 220 AGGMYFYSPTYLVKAQALCKQYGILLIFDEIATGFGRTGKLFAAEHAGISP---DIMCIG-KALTGGyLTLSASITTTEI 295 Haemophilus influenzae P30268 223 EGGYIIPPASWLAKVREICNRHDILLIFDEVQTGFGRTGEWFAAQTFGVTP---DIMAIA-KGIASG-LPLSATVANHTL 297 Bacillus pseudofirmus P14010 297 EGGDNHASPAFFRGLREITKRNNVLFIVDEVQTGVGATGKFWAHDHWNLETp-pDMVTFSkKAQTAGyYFGNPALRPNKP 375 Emericella nidulans P40829 234 EGGFIVPAEGFLATLLDWCRKNNVMFIADEVQTGFARTGAMFACEHDGIVP---DLICTA-KGIADG-LPLAAVTGRAEI 308 Mycobacterium leprae P80404 298 EGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDp-aDVMTFSkKMMTGG-FFHKEEFRPNAP 375 human P46716 223 NMGVVPPAPGYNAALRAITAEHGALLIIDEVMTGF-RVSRSG---WYGLDPvaaDLFIFG-KVMSGG-MPAAAFGGRAEV 296 Mycobacterium leprae
1SF2_A 286 MDAVapg---------glgGTYAGNPIACVAALEVLKVFEQENLLQKANDLGQKLKDGLL-AIAEKh-PEIGDVRGL--G 352 Escherichia coli P28269 307 YQTFmnqptpeyavefphgYTYSAHPVACAAGLAALCLLQKENLVQSVAEVAPHFEKALH-GIKGA--KNVIDIRNF--G 381 Pseudomonas putida P22805 304 YQAFyddyatm--kaflhsHSYTGNTLACRVALEVLAIFEEEQYIDVVQDKGERMRKLALeAFSDL--PFVGEYRQV--G 377 Lysinibacillus sphaer... P46395 291 AQLIstpngg---galmhgPTFMANPLACAVSHASLEIIETGMWQKQVKRIEAELIAGLS-PLQHL--PGVADVRVL--G 362 Corynebacterium gluta... P44426 296 AQTIcsgeak----cfmhgPTFMANPLACAIAAESIRLLLESPWQQNIQRIESSLKQQLS-PLSEK--DYVKEVRAL--G 366 Haemophilus influenzae P30268 298 MQQWplg---------shgTTFGGNPIACSAALATLDVLKEENLLDNAREVGAYARERLN-LLKEKy-EMIGSIRSV--G 364 Bacillus pseudofirmus P14010 376 YRQF---------------NTWMGDPSRALIFRGIIEEIERLFLVENTAATGDYLYSGLE-RLAKQypEHLQNLRGKgqG 439 Emericella nidulans P40829 309 MNAPhvs---------glgGTFGGNPVACAAALATITTIENDGLIQRAQQIERLITDRLL-RLQDAd-DRIGDVRGR--G 375 Mycobacterium leprae P80404 376 YRIF---------------NTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLL-DLQARypQFISRVRGR--G 437 human P46716 297 MERLaplgp------vyqaGTLSGNPVAMAAGLATLRAAADA-VYATLDRNADRLVAMLSeALTDA--GVPHQIPRA--G 365 Mycobacterium leprae
1SF2_A 353 AMIAIELFE 361 Escherichia coli P28269 382 LAGAIQIAP 390 Pseudomonas putida P22805 378 FVGAIELVA 386 Lysinibacillus sphaericus P46395 363 AIGVIEMEQ 371 Corynebacterium glutamicum P44426 367 AIGVVEMKS 375 Haemophilus influenzae P30268 365 LMIGIEIID 373 Bacillus pseudofirmus P14010 440 TFIAWDTPK 448 Emericella nidulans P40829 376 AMIAVELVK 384 Mycobacterium leprae P80404 438 TFCSFDTPD 446 human P46716 366 NMFSVFFSE 374 Mycobacterium leprae
Jiyao W et al.(2023). "The conserved domain database in 2023.",