Chromosome 3

VHL. Microscopic section of hemangioblastoma, a tumor of the cerebellum characteriztically found in patients with von Hippel-Lindau disease IMAGE CREDIT: Kevin Roth and Robert Schmidt, Washington University, St. Louis, MO, USA SCLC1. Deletion of a tumor suppressor gene is associated with one type of lung cancer. A large tumor (Ca) of the lung is visible in this CT scan IMAGE CREDIT: Pat Connelly, Miami Valley Hospital, Dayton, OH, USA MLH1. For this gene, as for MSH2, homologies to genes in DNA repair pathways in model organisms such as yeast shed light on human pathology