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| env | gag | nef | pol | rev | tat | vif | vpr | vpu |
| Pol | binds | major histocompatibility complex, class I, A precursor  |
| integrase | acetylated by | MYST histone acetyltransferase (monocytic leukemia) 4 |
| MYST histone acetyltransferase 1 | ||
| MYST histone acetyltransferase 2 | ||
| MYST3: MYST histone acetyltransferase (monocytic leukemia) 3 | ||
| activated by | hepatoma-derived growth factor, related protein 3 | |
| associates with | ATP-dependent DNA helicase II | |
| ATP-dependent DNA helicase II, 70 kDa subunit | ||
| binds | chaperonin containing TCP1, subunit 4 (delta) | |
| cyclin domain containing | ||
| cytosolic phosphoenolpyruvate carboxykinase 1 | ||
| eukaryotic translation elongation factor 1 alpha 1 | ||
| karyopherin alpha 1 | ||
| karyopherin alpha 2 | ||
| karyopherin alpha 3 | ||
| karyopherin alpha 4 | ||
| karyopherin alpha 5 (importin alpha 6) | ||
| karyopherin alpha 6 | ||
| karyopherin beta 1 | ||
| PC4 and SFRS1 interacting protein 1 isoform 1 | ||
| RAN binding protein 5 | ||
| SMN-interacting protein 1 isoform alpha | ||
| SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 isoform a | ||
| transportin 1 | ||
| uracil-DNA glycosylase isoform UNG2 | ||
| co-localizes with | hepatoma-derived growth factor-related protein 2 isoform 2 | |
| PC4 and SFRS1 interacting protein 1 isoform 1 | ||
| degraded by | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | |
| proteasome (prosome, macropain) activator subunit 4 | ||
| proteasome 26S ATPase subunit 1 | ||
| proteasome 26S ATPase subunit 2 | ||
| proteasome 26S ATPase subunit 3 | ||
| proteasome 26S ATPase subunit 4 isoform 1 | ||
| proteasome 26S ATPase subunit 5 | ||
| proteasome 26S ATPase subunit 6 | ||
| proteasome 26S non-ATPase subunit 1 | ||
| proteasome 26S non-ATPase subunit 10 isoform 1 | ||
| proteasome 26S non-ATPase subunit 11 | ||
| proteasome 26S non-ATPase subunit 12 | ||
| proteasome 26S non-ATPase subunit 13 isoform 1 | ||
| proteasome 26S non-ATPase subunit 2 | ||
| proteasome 26S non-ATPase subunit 3 | ||
| proteasome 26S non-ATPase subunit 4 isoform 1 | ||
| proteasome 26S non-ATPase subunit 5 | ||
| proteasome 26S non-ATPase subunit 7 | ||
| proteasome 26S non-ATPase subunit 8 | ||
| proteasome 26S non-ATPase subunit 9 | ||
| proteasome activator subunit 1 isoform 1 | ||
| proteasome activator subunit 2 | ||
| proteasome activator subunit 3 isoform 1 | ||
| proteasome alpha 1 subunit isoform 2 | ||
| proteasome alpha 2 subunit | ||
| proteasome alpha 3 subunit isoform 1 | ||
| proteasome alpha 4 subunit | ||
| proteasome alpha 5 subunit | ||
| proteasome alpha 6 subunit | ||
| proteasome alpha 7 subunit | ||
| proteasome beta 1 subunit | ||
| proteasome beta 10 subunit proprotein | ||
| proteasome beta 2 subunit | ||
| proteasome beta 3 subunit | ||
| proteasome beta 4 subunit | ||
| proteasome beta 5 subunit | ||
| proteasome beta 6 subunit | ||
| proteasome beta 7 subunit proprotein | ||
| proteasome beta 8 subunit isoform E1 proprotein | ||
| proteasome beta 9 subunit isoform 1 proprotein | ||
| proteasome inhibitor subunit 1 isoform 1 | ||
| imported by | importin 7 | |
| karyopherin alpha 1 | ||
| karyopherin alpha 2 | ||
| karyopherin alpha 3 | ||
| karyopherin alpha 4 | ||
| karyopherin alpha 5 (importin alpha 6) | ||
| karyopherin alpha 6 | ||
| karyopherin beta 1 | ||
| PC4 and SFRS1 interacting protein 1 isoform 1 | ||
| RAN binding protein 5 | ||
| transportin 1 | ||
| incorporates | cyclin domain containing | |
| uracil-DNA glycosylase isoform UNG2 | ||
| inhibited by | RAD51 homolog protein isoform 1 | |
| SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 isoform a | ||
| interacts with | ataxia telangiectasia and Rad3 related protein | |
| ataxia telangiectasia mutated protein isoform 1 | ||
| ATP-dependent DNA helicase II | ||
| ATP-dependent DNA helicase II, 70 kDa subunit | ||
| barrier to autointegration factor 1 | ||
| embryonic ectoderm development isoform a | ||
| emerin | ||
| heat shock 10kDa protein 1 (chaperonin 10) | ||
| PC4 and SFRS1 interacting protein 1 isoform 1 | ||
| postreplication repair protein hRAD18p | ||
| promyelocytic leukemia protein isoform 1 | ||
| protein kinase, DNA-activated, catalytic polypeptide | ||
| SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 isoform a | ||
| recruits | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 isoform a | |
| regulated by | PC4 and SFRS1 interacting protein 1 isoform 1 | |
| requires | poly (ADP-ribose) polymerase family, member 1 | |
| stimulated by | chaperonin | |
| embryonic ectoderm development isoform a | ||
| high mobility group AT-hook 1 isoform b | ||
| PC4 and SFRS1 interacting protein 1 isoform 1 | ||
| SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 isoform a | ||
| stimulates | flap structure-specific endonuclease 1 | |
| retropepsin | activated by | glutaredoxin 2 isoform 1 |
| glutaredoxin 5 | ||
| activates | caspase 3 preproprotein | |
| caspase 8 isoform A precursor | ||
| caspase 9 isoform alpha preproprotein | ||
| cleaves | actin, gamma 1 propeptide | |
| actin, gamma 2 propeptide | ||
| actinin, alpha 1 | ||
| alpha 1 actin precursor | ||
| alpha 2 actin | ||
| alpha-2-macroglobulin precursor | ||
| amyloid beta A4 protein precursor, isoform a | ||
| B-cell lymphoma protein 2 alpha isoform | ||
| beta actin | ||
| calmodulin 1 | ||
| cardiac muscle alpha actin 1 proprotein | ||
| complement component 1 inhibitor precursor | ||
| desmin | ||
| eukaryotic translation initiation factor 4 gamma, 1 isoform 1 | ||
| fast skeletal muscle troponin C | ||
| fibronectin 1 isoform 1 preproprotein | ||
| filamin A, alpha | ||
| filamin B, beta (actin binding protein 278) | ||
| gamma filamin | ||
| glial fibrillary acidic protein | ||
| integrin alpha 3 isoform a precursor | ||
| integrin beta 4 isoform 1 precursor | ||
| interleukin 1, beta proprotein | ||
| L-plastin | ||
| microtubule-associated protein 1 light chain 3 alpha isoform a | ||
| microtubule-associated protein 1 light chain 3 gamma | ||
| microtubule-associated protein 1A | ||
| microtubule-associated protein 2 isoform 1 | ||
| microtubule-associated proteins 1A/1B light chain 3 | ||
| myosin heavy chain 6 | ||
| myosin, heavy chain 14 isoform 2 | ||
| myosin, heavy chain 7, cardiac muscle, beta | ||
| myosin, heavy polypeptide 10, non-muscle | ||
| myosin, heavy polypeptide 13, skeletal muscle | ||
| myosin, heavy polypeptide 9, non-muscle | ||
| N-myc downstream regulated gene 1 | ||
| N-myc downstream-regulated gene 2 isoform a | ||
| nuclear factor kappa-B, subunit 1 | ||
| phosphorylase kinase, alpha 1 (muscle) | ||
| phosphorylase kinase, alpha 2 (liver) | ||
| phosphorylase kinase, beta isoform a | ||
| plastin 1 | ||
| plastin 3 | ||
| poly (ADP-ribose) polymerase family, member 1 | ||
| poly (ADP-ribose) polymerase family, member 4 | ||
| poly(A) binding protein, cytoplasmic 1 | ||
| pro-platelet basic protein precursor | ||
| smooth muscle myosin heavy chain 11 isoform SM1A | ||
| spectrin beta isoform b | ||
| spectrin, alpha, erythrocytic 1 | ||
| spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) | ||
| spectrin, beta, non-erythrocytic 1 isoform 1 | ||
| spectrin, beta, non-erythrocytic 2 | ||
| spectrin, beta, non-erythrocytic 4 isoform sigma1 | ||
| spectrin, beta, non-erythrocytic 5 | ||
| talin 1 | ||
| talin 2 | ||
| tropomyosin 1 alpha chain isoform 5 | ||
| troponin C, slow | ||
| vimentin | ||
| degrades | tropomyosin 1 alpha chain isoform 5 | |
| tropomyosin 2 (beta) isoform 1 | ||
| tropomyosin 3 isoform 1 | ||
| vimentin | ||
| downregulates | B-cell lymphoma protein 2 alpha isoform | |
| induces cleavage of | BH3 interacting domain death agonist isoform 1 | |
| DNA fragmentation factor, 40 kD, beta polypeptide isoform 1 | ||
| DNA fragmentation factor, 45kDa, alpha polypeptide isoform 1 | ||
| poly (ADP-ribose) polymerase family, member 1 | ||
| poly (ADP-ribose) polymerase family, member 4 | ||
| induces release of | cytochrome c | |
| inhibited by | lysyl-tRNA synthetase | |
| protein kinase C, alpha | ||
| protein kinase C, beta isoform 2 | ||
| protein kinase C, delta | ||
| protein kinase C, epsilon | ||
| protein kinase C, eta | ||
| protein kinase C, gamma | ||
| protein kinase C, iota | ||
| protein kinase C, theta | ||
| protein kinase C, zeta isoform 1 | ||
| phosphorylated by | casein kinase 2, alpha prime polypeptide | |
| casein kinase 2, beta polypeptide | ||
| casein kinase II alpha 1 subunit isoform a | ||
| reverse transcriptase | binds | beta actin |
| co-localizes with | actin, gamma 1 propeptide | |
| actin, gamma 2 propeptide | ||
| alpha 1 actin precursor | ||
| alpha 2 actin | ||
| beta actin | ||
| cardiac muscle alpha actin 1 proprotein | ||
| degraded by | interferon, gamma | |
| proteasome beta 8 subunit isoform E1 proprotein | ||
| enhanced by | DNA topoisomerase I | |
| nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 isoform B | ||
| nuclear factor of activated T-cells, cytosolic component 1 isoform A | ||
| fractionates with | nucleolin | |
| imported by | importin 7 | |
| inhibited by | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | |
| interferon, alpha 1 | ||
| interferon, alpha 16 | ||
| interferon, alpha 2 | ||
| interferon, alpha 7 | ||
| interleukin 10 precursor | ||
| interleukin 13 precursor | ||
| replication protein A1, 70kDa | ||
| replication protein A2, 32kDa | ||
| replication protein A3, 14kDa | ||
| replication protein A4, 34kDa | ||
| interacts with | hepatoma-derived growth factor, related protein 3 | |
| mitogen-activated protein kinase 1 | ||
| mitogen-activated protein kinase 12 | ||
| mitogen-activated protein kinase 3 isoform 1 | ||
| mitogen-activated protein kinase kinase 1 |