Caenorhabditis elegans gene hap-1, encoding yeast HydroxylAminoPurine sensitivity related.
TABLE OF CONTENTS / OPEN CLOSE ALL PARAGRAPHS
SUMMARY back to top
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Wormbase predicts one model
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AceView summary
According to AceView, this gene is moderately expressed, only 22.8% of the average gene in this release. The sequence of this gene is defined by 3 cDNA clones. We annotate structural defects or features in one cDNA clone.
The gene contains 4 distinct gt-ag introns. Transcription produces one mRNA.
The spliced mRNA putatively encodes a good protein, altogether 2 different isoforms (2 COOH complete), containing Ham1-like protein domain [Pfam].
Function: There are 2 articles specifically referring to this gene in PubMed. In addition we point below to one abstract. Proteins are expected to have molecular function (hydrolase activity). No phenotype has yet been reported to our knowledge: this gene's in vivo function is yet unknown.

Please quote: AceView: a comprehensive cDNA-supported gene and transcripts annotation, Genome Biology 2006, 7(Suppl 1):S12
Map on chromosome CHROMOSOME_III, links to other databases and other names back to top ?
Map: This gene hap-1 maps on chomosome III at position -1.90 (interpolated). In AceView, it covers 1.05 kb, from 5263903 to 5264955 (WS190), on the direct strand.
Links to: WormBase, NextDB, RNAiDB.
Other names: The gene is also known in Wormgenes/AceView by its positional name 3G353, in Wormbase by its cosmid.number name ZC395.7, in NextDB, the Nematode expression pattern database, as CEYK7921.
Closest AceView homologs in other species back to top ?
The closest human gene, according to BlastP, is the AceView gene ITPA (e=7 10^-59).
The closest mouse genes, according to BlastP, are the AceView genes Itpa-ps1 (e=6 10^-60), Itpa (e=6 10^-60).
The closest A.thaliana gene, according to BlastP, is the AceView gene AT4G13720 (e=10^-46)
Complete gene on genome diagram:               (in true scale, with colored introns) back to top
Compact gene diagram back to top
Legend
Sequences back to top
What is known about the gene and its neighbors on chromosome CHROMOSOME_III back to top
ZOOM IN                D:disease,C:conserved,I:interactions,R:regulation,P:publications         (see the Legend)
Annotated mRNA diagrams back to top
Bibliography back to top
? Gene Summary Gene on genome mRNA Expression Tissue Function and related genes CI

To mine knowledge about the gene, please click the 'Gene Summary' or the 'Function and related genes' tab at the top of the page. The 'Gene Summary' page includes all we learnt about the gene, functional annotations of neighboring genes, maps, links to other sites and the bibliography. The 'Function and related genes' page includes Diseases (D), Pathways, GO annotations, conserved domains (C), interactions (I) reference into function, and pointers to all genes with the same functional annotation.
To see the mRNA diagram, sequence and annotation, click the 'mRNA' tab. To examine expression data from all cDNAs clustered in this gene by AceView, click the 'Expression tissue'.

If you know more about this gene, or found errors, please share your knowledge. Merci !