.
Wormbase predicts one model.
AceView summary
According to AceView, this gene is
moderately expressed, only 30.4% of the average gene in this release, down regulated in dauer [SAGE, Jones et al, 2001]. The
sequence of this gene is defined by
4 cDNA clones.
The gene contains
8 distinct gt-ag introns. Transcription produces one mRNA.
The spliced mRNA putatively encodes
a good protein, containing tRNA isopentenyltransferase
domain [Pfam].
Function: There are
8 articles specifically referring to this gene in PubMed. In addition we point
below to 20 abstracts. This gene is associated to a
phenotype (abnormal GROwth rate, maternal rescue, regulates metabolic activity, SLow growth, extends adult lifespan). Functionally, the gene has been proposed to participate in a
process (tRNA processing). Proteins are expected to have molecular
functions (ATP binding activity, tRNA isopentenyltransferase activity).
Please quote:
AceView: a comprehensive cDNA-supported gene and transcripts annotation, Genome Biology 2006, 7(Suppl 1):S12
Map: This gene gro-1 maps on chomosome III at position -1.89 (interpolated). In AceView, it covers
2.10 kb, from 5265072 to 5267169 (WS190), on the direct strand.
Links to: WormBase,
NextDB,
RNAiDB.
Other names: The gene is also known in Wormgenes/AceView by its positional name 3G355, in Wormbase by its cosmid.number name ZC395.6, in NextDB, the Nematode expression pattern database, as CEYK9178.
The closest human gene, according to BlastP, is the AceView gene
TRIT1 (e=4 10^-46).
The closest mouse gene, according to BlastP, is the AceView gene
Trit1 (e=8 10^-48).
The closest A.thaliana gene, according to BlastP, is the AceView gene
ATIPT2 (e=4 10^-33)
Legend
Introns are depicted by broken lines; the height of the top of each intron reflects the relative number of clones supporting this intron.
]^[ A pink broken line denotes an intron with standard boundaries (gt-ag or gc-ag) that is exactly supported (i.e. a cDNA sequence exactly matches the genome over 16 bp, 8 on both sides of the intron).
] ^ ] A blue broken line denotes non-standard introns, exactly supported, but with non-standard at-ac or any other boundaries.
]-[ Pink and
] - ] blue straight lines represent 'fuzzy' introns of the standard and non-standard types respectively, those introns do not follow the 16 bp rule. Black straight lines ]-[denote gaps in the alignments.
Exons: Wide filled pink areas represent putative protein coding regions, narrow empty pink boxes represent the 5'UTR (on the left) and 3' UTR (on the right). Flags identify validated endings: cap site on the 5' side, polyadenylation site on the 3' side. Filled flags correspond to frequent events while empty flags have lesser supporting cDNAs (yet all are validated); at the 3' side, black flags are associated to the main AATAAA signal,
blue flags to any single letter variant of the main . More explanations are given in the
gene help file
