Caenorhabditis elegans gene dnj-2, encoding DNaJ domain (prokaryotic heat shock protein).
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SUMMARY back to top
Summary
[Wormbase] This gene encodes a protein containing a DnaJ ('J') domain.
Wormbase predicts one model
.

AceView summary
According to AceView, this gene is well expressed, 0.6 times the average gene in this release, at all stages of development [Kohara cDNAs]. The sequence of this gene is defined by 8 cDNA clones.
The gene contains 5 distinct gt-ag introns. Transcription produces one mRNA. There are 2 validated alternative polyadenylation sites (see the diagram). 322 bp of this gene are antisense to spliced gene 4M77, raising the possibility of regulated alternate expression.
The spliced mRNA putatively encodes a good protein, containing heat shock protein DnaJ, N-terminal domain [Pfam], a coiled coil stretch [Psort2] Proteins are expected to localize in membrane. No phenotype has yet been reported to our knowledge: this gene's in vivo function is yet unknown.

Please quote: AceView: a comprehensive cDNA-supported gene and transcripts annotation, Genome Biology 2006, 7(Suppl 1):S12
Map on chromosome CHROMOSOME_IV, links to other databases and other names back to top ?
Map: This gene dnj-2 maps on chomosome IV at position +5.20 (interpolated). In AceView, it covers 1.54 kb, from 11313951 to 11312413 (WS190), on the reverse strand.
Links to: WormBase, NextDB, RNAiDB.
Other names: The gene is also known in Wormgenes/AceView by its positional name 4M78, in Wormbase by its cosmid.number name B0035.2, in NextDB, the Nematode expression pattern database, as CEYK2276.
Closest AceView homologs in other species back to top ?
The closest human gene, according to BlastP, is the AceView gene bA16L21.2.1andGNG10 (e=2 10^-42).
The closest mouse gene, according to BlastP, is the AceView gene 2010203O07Rik (e=2 10^-42).
The closest A.thaliana gene, according to BlastP, is the AceView gene AT1G61770 (e=2 10^-28)
Complete gene on genome diagram:               (in true scale, with colored introns) back to top
Compact gene diagram back to top
Legend
Sequences back to top
What is known about the gene and its neighbors on chromosome CHROMOSOME_IV back to top
ZOOM IN                D:disease,C:conserved,I:interactions,R:regulation,P:publications         (see the Legend)
Annotated mRNA diagrams back to top
? Gene Summary Gene on genome mRNA Expression Tissue Function and related genes C

To mine knowledge about the gene, please click the 'Gene Summary' or the 'Function and related genes' tab at the top of the page. The 'Gene Summary' page includes all we learnt about the gene, functional annotations of neighboring genes, maps, links to other sites and the bibliography. The 'Function and related genes' page includes Diseases (D), Pathways, GO annotations, conserved domains (C), interactions (I) reference into function, and pointers to all genes with the same functional annotation.
To see the mRNA diagram, sequence and annotation, click the 'mRNA' tab. To examine expression data from all cDNAs clustered in this gene by AceView, click the 'Expression tissue'.

If you know more about this gene, or found errors, please share your knowledge. Merci !