Caenorhabditis elegans essential gene byn-1, encoding mammalian BYstiN (adhesion protein) related.
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SUMMARY back to top
Summary
[Wormbase] byn-1 encodes a homolog of mammalian BYSTIN-LIKE (BYSL; OMIM:603871).
Wormbase predicts one model
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AceView summary
According to AceView, this gene is expressed at very high level, 4.8 times the average gene in this release, at all stages of development [Kohara cDNAs]. The sequence of this gene is defined by 63 cDNA clones, some from whole animal (seen 5 times). We annotate structural defects or features in 5 cDNA clones.
The gene contains 9 distinct gt-ag introns. Transcription produces one mRNA. There are 2 validated alternative polyadenylation sites (see the diagram).
The spliced mRNA putatively encodes a good protein, containing Bystin domain [Pfam].
Function:. This essential gene is associated to a phenotype (Embryonic Lethal, Protruding VuLva, SLow growth, Sterile adult).

Please quote: AceView: a comprehensive cDNA-supported gene and transcripts annotation, Genome Biology 2006, 7(Suppl 1):S12
Map on chromosome CHROMOSOME_III, links to other databases and other names back to top ?
Map: This essential gene byn-1 maps on chomosome III at position -0.92 (interpolated). In AceView, it covers 3.86 kb, from 6931937 to 6935798 (WS190), on the direct strand.
Links to: WormBase, NextDB, RNAiDB.
Other names: The gene is also known in Wormgenes/AceView by its positional name 3I25, in Wormbase by its cosmid.number name F57B9.5, in NextDB, the Nematode expression pattern database, as CEYK6101.
Closest AceView homologs in other species back to top ?
The closest human gene, according to BlastP, is the AceView gene BYSL (e= 10^-114).
The closest mouse gene, according to BlastP, is the AceView gene Bysl (e= 10^-111).
The closest A.thaliana gene, according to BlastP, is the AceView gene AT1G31660 (e=2 10^-82)
Complete gene on genome diagram:               (in true scale, with colored introns) back to top
Compact gene diagram back to top
Legend
Sequences back to top
What is known about the gene and its neighbors on chromosome CHROMOSOME_III back to top
ZOOM IN                D:disease,C:conserved,I:interactions,R:regulation,P:publications         (see the Legend)
Annotated mRNA diagrams back to top
Bibliography back to top
? Gene Summary Gene on genome mRNA Expression Tissue Function and related genes DC

To mine knowledge about the gene, please click the 'Gene Summary' or the 'Function and related genes' tab at the top of the page. The 'Gene Summary' page includes all we learnt about the gene, functional annotations of neighboring genes, maps, links to other sites and the bibliography. The 'Function and related genes' page includes Diseases (D), Pathways, GO annotations, conserved domains (C), interactions (I) reference into function, and pointers to all genes with the same functional annotation.
To see the mRNA diagram, sequence and annotation, click the 'mRNA' tab. To examine expression data from all cDNAs clustered in this gene by AceView, click the 'Expression tissue'.

If you know more about this gene, or found errors, please share your knowledge. Merci !