Homo sapiens complex locus DGCR6, encoding DiGeorge syndrome critical region gene 6.
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SUMMARY back to top
RefSeq summary
[DGCR6] DiGeorge syndrome, and more widely, the CATCH 22 syndrome, are associated with microdeletions in chromosomal region 22q11.2. The product of this gene shares homology with the Drosophila melanogaster gonadal protein, which participates in gonadal and germ cell development, and with the gamma-1 subunit of human laminin. This gene is a candidate for involvement in DiGeorge syndrome pathology and in schizophrenia. [provided by RefSeq].

RefSeq annotates one representative transcript (NM included in AceView variant.a), but Homo sapiens cDNA sequences in GenBank, dbEST, Trace and SRA, filtered against clone rearrangements, coaligned on the genome and clustered in a minimal non-redundant way by the manually supervised AceView program, support at least 12 spliced variants.

AceView synopsis, each blue text links to tables and details
Note that this locus is complex: it appears to produce several proteins with no sequence overlap.
Expression: According to AceView, this gene is expressed at high level, 1.4 times the average gene in this release. The sequence of this gene is defined by 164 GenBank accessions from 149 cDNA clones, some from brain (seen 17 times), cerebellum (15), pectoral muscle (after mastectomy) (13), hypothalamus (10), eye (8), skeletal muscle (7), prostate (6) and 55 other tissues. We annotate structural defects or features in 3 cDNA clones.
Alternative mRNA variants and regulation: The gene contains 13 distinct introns (12 gt-ag, 1 gc-ag). Transcription produces 15 different mRNAs, 12 alternatively spliced variants and 3 unspliced forms. There are 5 probable alternative promotors, 3 non overlapping alternative last exons and 4 validated alternative polyadenylation sites (see the diagram). The mRNAs appear to differ by truncation of the 5' end, truncation of the 3' end, presence or absence of a cassette exon, overlapping exons with different boundaries.
2 variants were isolated in vivo, despite the fact that they are predicted targets of nonsense mediated mRNA decay (NMD).
Efficacy of translation may be reduced by the presence of a shorter translated product (uORF) initiating at an AUG upstream of the main open reading frame (in variant cAug10).
Function: There are 9 articles specifically referring to this gene in PubMed. Functionally, the gene has been tested for association to diseases (DiGeorge syndrome; Schizophrenia) and proposed to participate in processes (cell adhesion, organ morphogenesis). Proteins are expected to localize in various compartments (proteinaceous extracellular matrix, nucleus).
Protein coding potential: 12 spliced and 2 unspliced mRNAs putatively encode good proteins, altogether 14 different isoforms (11 complete, 2 COOH complete, 1 partial), some containing DiGeorge syndrome critical region 6 (DGCR6) protein domain [Pfam], a N-myristoylation domain, a coiled coil stretch [Psort2]. The remaining mRNA variant (unspliced) appears not to encode a good protein.

Please quote: AceView: a comprehensive cDNA-supported gene and transcripts annotation, Genome Biology 2006, 7(Suppl 1):S12.
Map on chromosome 22, links to other databases and other names
Map: This gene DGCR6 maps on chromosome 22, at 22q11.21|22q11 according to Entrez Gene. In AceView, it covers 6.78 kb, from 18893084 to 18899859 (NCBI 37, August 2010), on the direct strand.
Links to: the SNP view, gene overviews from Entrez Gene 8214, GeneCards, expression data from ECgene, UniGene, molecular and other annotations from UCSC, or our GOLD analysis.
The previous AceView annotation is here.
Other names: The gene is also known as DGCR6, LOC8214. It has been described as protein DGCR6, DiGeorge syndrome critical region protein 6.
Closest AceView homologs in other species ?
The closest mouse gene, according to BlastP, is the AceView gene Dgcr6 (e=6 10-24).
The closest A.thaliana gene, according to BlastP, is the AceView gene AT5G08460 (e=0.20)
RNA_seq discoveries back to top
Expression/conservation in primates tissues evaluated by cross-mapping to human. back to top
DGCR6 Gene expression in 15 primates, 16 tissues, from the NHPRTR project in sFPKM BAB SkeletalMuscle WholeBlood CHP Kidney Liver Lung Spleen CMC CMM Cerebellum HUM Brain Colon Heart LymphNode Ovary Testis JMI BoneMarrow MLM OWL PTM RMC RMI Pituitary SQM Thymus MST SMY RTL 1.26 2.19 2.90 2.19 1.10 24.8 1.18 0.83 3.33 8.19 3.57 13.3 6.65 12.4 10.1 21.6 6.65 6.21 32.8 4.71 24.8 3.82 2.90 0.78 2.05 7.64 4.39 3.57 2.52 4.10 2.19 3.57 14.3 16.4 13.3 4.71 6.65 4.71 1.91 4.71 4.39 10.8 3.82 2.70 0.63 4.39 6.65 1.35 2.90 5.04 8.78 6.21 2.35 3.57 3.10 3.57 5.40 3.57 1.66 2.70 1.45 0.59 4.39 3.57 4.71 2.05 6.21 8.78 4.71 5.79 3.10 2.52 2.90 3.33 5.79 3.82 5.79 5.04 7.64 3.10 5.79 3.82 2.90 8.78 5.04 4.71 4.10 3.33 6.65 6.21 4.10 2.70 2.90 6.65 2.90 6.65 6.65 5.04 5.79 7.64 7.13 6.21 8.78 5.04 5.40 5.40 8.78 3.10 5.04 3.10 4.39 2.70 2.35 3.82 2.70 2.35 5.79 6.21 5.40 4.71 2.52 3.57 4.39 1.45 2.19 1.91 7.13 3.82 2.52 3.10 4.10 1.55 1.78 0.63 0.55 0.45 3.82 5.79 3.57 5.79 2.35 3.82 1.66 4.39 1.55 5.40 6.21 4.71 2.05 3.82 1.91 Expression quantiles None Weak 1 2 3 4 5 6 7 8 10 20 This gene All genes log2 distributions RNA-seq gene expression profile across 16 selected tissues from the Non-Human Primates Reference Transcriptome Resource (link to NHPRTR project).
- Primates: Apes (HUM: Human (Illumina BodyMap 2), CHP: Chimpanzee), Old World monkeys (PTM: Pig-Tailed Macaque, JMI Japanese Macaque, RMI Rhesus Macaque Indian, RMC Rhesus Macaque Chinese, CMM Cynomolgus Macaque Mauritian, CMC Cynomolgus Macaque Chinese, BAB Olive Baboon, SMY Sooty Mangabey); New World monkeys (MST common Marmoset, SQM Squirrel Monkey, OWL Owl Monkey); and Lemurs (MLM Mouse Lemur, RTL Ring-Tailed Lemur).
- The level for significantly expressed genes is color coded in 8 equal sized bins (light to dark green). Light gray is for weak not-accurately measured expression (2 to 8 reads above intergenic background); dark gray for no expression or no sequence conservation (0 read in gene). The plot to the right shows the distribution of measured expression values in all tissues for all genes (blue) and for this gene (green), in Magic index = log2(1000 sFPKM).
You may also examine the strand-specific genome coverage plots on the experimental AceView/Magic hub at UCSC, by tissue or by species. Tracks may be slow to load; please reload if some tracks come up yellow-greenish, and thanks to UCSC for the great work!.
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          Complete gene on genome diagram: back to top
Please choose between the zoomable GIF version., and the HTML5/SVG version.
This diagram shows in true scale the gene on the genome, the mRNAs and the cDNA clones.
Compact gene diagram back to top
Gene DGCR6 5' 3' encoded on plus strand of chromosome 22 from 18,893,084 to 18,899,859 33064 29422 41514 a [NM] 218 33064 29422 41514 b 4 29422 41514 c 1336 1276 29422 d e 44 29422 i 218 1336 1276 29422 41514 f 1 29422 41514 g 16 29422 h m 41514 j l-u o-u k-u 1123 29422 n 1kb 0 262 bp exon 262 bp exon 80 bp [gt-ag] intron 80 GenBank accessions 44998 RNA-seq supporting reads 1984 UHR pooled cells 14029 Brain 352 Blood 28172 Neuroblastoma 461 Other (also 24 Primates bodymap) 161 bp exon 3446 bp [gt-ag] intron 54 GenBank accessions 33010 RNA-seq supporting reads 1721 UHR pooled cells 9800 Brain 352 Blood 20760 Neuroblastoma 377 Other (also 35 Primates bodymap) 101 bp exon 615 bp [gt-ag] intron 63 GenBank accessions 29359 RNA-seq supporting reads 1501 UHR pooled cells 9241 Brain 334 Blood 17920 Neuroblastoma 363 Other (also 4661 Primates bodymap) 141 bp exon 511 bp [gt-ag] intron 41 GenBank accessions 41473 RNA-seq supporting reads 2031 UHR pooled cells 12501 Brain 744 Blood 25793 Neuroblastoma 404 Other (also 3845 Primates bodymap) 548 bp exon 51 accessions, NM_005675.4 some from cerebellum (seen 9 times) skeletal muscle (6), eye (4) hypothalamus (4), brain (3) capped 5' end, 19 accessions Validated 3' end, 5 accessions 548 bp exon 87 bp exon 87 bp exon 450 bp [gt-ag] intron 3 GenBank accessions 215 RNA-seq supporting reads 25 UHR pooled cells 84 Brain 105 Neuroblastoma 1 Other 161 bp exon 3446 bp [gt-ag] intron 54 GenBank accessions 33010 RNA-seq supporting reads 1721 UHR pooled cells 9800 Brain 352 Blood 20760 Neuroblastoma 377 Other (also 35 Primates bodymap) 101 bp exon 615 bp [gt-ag] intron 63 GenBank accessions 29359 RNA-seq supporting reads 1501 UHR pooled cells 9241 Brain 334 Blood 17920 Neuroblastoma 363 Other (also 4661 Primates bodymap) 141 bp exon 511 bp [gt-ag] intron 41 GenBank accessions 41473 RNA-seq supporting reads 2031 UHR pooled cells 12501 Brain 744 Blood 25793 Neuroblastoma 404 Other (also 3845 Primates bodymap) 807 bp exon 16 accessions, some from prostate (seen 4 times) kidney (3), brain (once) cerebellum (once), cochlea (once) Validated 3' end, 4 accessions 807 bp exon 142 bp exon 142 bp exon 435 bp uORF 80 bp [gt-ag] intron 80 GenBank accessions 44998 RNA-seq supporting reads 1984 UHR pooled cells 14029 Brain 352 Blood 28172 Neuroblastoma 461 Other (also 24 Primates bodymap) 435 bp uORF 522 bp exon 522 bp exon 522 bp exon 3092 bp [gt-ag] intron 1 GenBank accession 3 RNA-seq supporting reads 1 Brain 1 Neuroblastoma 1 Other 94 bp exon 94 bp exon 615 bp [gt-ag] intron 63 GenBank accessions 29359 RNA-seq supporting reads 1501 UHR pooled cells 9241 Brain 334 Blood 17920 Neuroblastoma 363 Other (also 4661 Primates bodymap) 141 bp exon 141 bp exon 511 bp [gt-ag] intron 41 GenBank accessions 41473 RNA-seq supporting reads 2031 UHR pooled cells 12501 Brain 744 Blood 25793 Neuroblastoma 404 Other (also 3845 Primates bodymap) 553 bp exon 553 bp exon 52 accessions, some from pectoral muscle (after mastectomy) (seen 13 times) hypothalamus (6), brain (4) adrenal cortex carcinoma cell line (2), adrenal gland (2) capped 5' end, 4 accessions Validated 3' end, 12 accessions 553 bp exon 142 bp exon 142 bp exon 80 bp [gt-ag] intron 80 GenBank accessions 44998 RNA-seq supporting reads 1984 UHR pooled cells 14029 Brain 352 Blood 28172 Neuroblastoma 461 Other (also 24 Primates bodymap) 161 bp exon 3254 bp [gt-ag] intron 4 GenBank accessions 1332 RNA-seq supporting reads 70 UHR pooled cells 386 Brain 11 Blood 851 Neuroblastoma 14 Other 119 bp exon 73 bp [gt-ag] intron 3 GenBank accessions 1273 RNA-seq supporting reads 57 UHR pooled cells 398 Brain 1 Blood 799 Neuroblastoma 18 Other 101 bp exon 101 bp exon 615 bp [gt-ag] intron 63 GenBank accessions 29359 RNA-seq supporting reads 1501 UHR pooled cells 9241 Brain 334 Blood 17920 Neuroblastoma 363 Other (also 4661 Primates bodymap) 3 accessions, some from testis (seen 2 times) liver (once) 73 bp exon 199 bp exon 199 bp exon 80 bp [gt-ag] intron 80 GenBank accessions 44998 RNA-seq supporting reads 1984 UHR pooled cells 14029 Brain 352 Blood 28172 Neuroblastoma 461 Other (also 24 Primates bodymap) 823 bp exon 14 accessions, some from cerebellum (seen 3 times) brain (2), hippocampus (2) islets of langerhans (2) pancreas (2) capped 5' end, 6 accessions Validated 3' end, 1 accession 823 bp exon 47 bp exon 47 bp exon 1478 bp [gt-ag] intron 1 GenBank accession 43 RNA-seq supporting reads 26 Brain 16 Neuroblastoma 1 Other 101 bp exon 615 bp [gt-ag] intron 63 GenBank accessions 29359 RNA-seq supporting reads 1501 UHR pooled cells 9241 Brain 334 Blood 17920 Neuroblastoma 363 Other (also 4661 Primates bodymap) 351 bp exon 1 accession from cerebellum capped 5' end, 1 accession 351 bp exon 544 bp exon 544 bp exon 42 bp uORF 544 bp exon 544 bp exon 450 bp [gt-ag] intron 3 GenBank accessions 215 RNA-seq supporting reads 25 UHR pooled cells 84 Brain 105 Neuroblastoma 1 Other 161 bp exon 161 bp exon 3254 bp [gt-ag] intron 4 GenBank accessions 1332 RNA-seq supporting reads 70 UHR pooled cells 386 Brain 11 Blood 851 Neuroblastoma 14 Other 119 bp exon 119 bp exon 73 bp [gt-ag] intron 3 GenBank accessions 1273 RNA-seq supporting reads 57 UHR pooled cells 398 Brain 1 Blood 799 Neuroblastoma 18 Other 101 bp exon 101 bp exon 101 bp exon 615 bp [gt-ag] intron 63 GenBank accessions 29359 RNA-seq supporting reads 1501 UHR pooled cells 9241 Brain 334 Blood 17920 Neuroblastoma 363 Other (also 4661 Primates bodymap) 141 bp exon 511 bp [gt-ag] intron 41 GenBank accessions 41473 RNA-seq supporting reads 2031 UHR pooled cells 12501 Brain 744 Blood 25793 Neuroblastoma 404 Other (also 3845 Primates bodymap) 3 accessions, some from brain (seen once) hippocampus (once), placenta (once) pre-eclamptic placenta (once) 507 bp exon 92 bp exon 92 bp exon 3254 bp [gt-ag] intron 1 GenBank accession 101 bp exon 615 bp [gt-ag] intron 63 GenBank accessions 29359 RNA-seq supporting reads 1501 UHR pooled cells 9241 Brain 334 Blood 17920 Neuroblastoma 363 Other (also 4661 Primates bodymap) 141 bp exon 511 bp [gt-ag] intron 41 GenBank accessions 41473 RNA-seq supporting reads 2031 UHR pooled cells 12501 Brain 744 Blood 25793 Neuroblastoma 404 Other (also 3845 Primates bodymap) 411 bp exon 1 accession from bone from osteosarcoma cell line 411 bp exon 230 bp exon 230 bp exon 80 bp [gt-ag] intron 80 GenBank accessions 44998 RNA-seq supporting reads 1984 UHR pooled cells 14029 Brain 352 Blood 28172 Neuroblastoma 461 Other (also 24 Primates bodymap) 134 bp exon 3517 bp [gc-ag] intron 1 GenBank accession 15 RNA-seq supporting reads 2 UHR pooled cells 13 Brain 57 bp exon 57 bp exon 615 bp [gt-ag] intron 63 GenBank accessions 29359 RNA-seq supporting reads 1501 UHR pooled cells 9241 Brain 334 Blood 17920 Neuroblastoma 363 Other (also 4661 Primates bodymap) 1 accession from skeletal muscle capped 5' end, 1 accession 129 bp exon 158 bp exon 158 bp exon 97 bp [gt-ag] intron 1 GenBank accession 400 RNA-seq supporting reads 16 UHR pooled cells 102 Brain 282 Neuroblastoma (also 3 Primates bodymap) 36 bp exon 1 accession from stomach 36 bp exon 438 bp exon 438 bp exon 511 bp [gt-ag] intron 41 GenBank accessions 41473 RNA-seq supporting reads 2031 UHR pooled cells 12501 Brain 744 Blood 25793 Neuroblastoma 404 Other (also 3845 Primates bodymap) 345 bp exon 2 accessions, some from eye (seen once) eye anterior segment (once) 345 bp exon 108 bp uORF 570 bp exon 570 bp exon 570 bp exon 1 accession from brain capped 5' end, 1 accession 570 bp exon 781 bp exon 781 bp exon 3 accessions, some from brain (seen once) breast (once), cerebellum (once) marrow (once) 781 bp exon 581 bp exon 581 bp exon 270 bp uORF 581 bp exon 581 bp exon 1 accession from brain capped 5' end, 1 accession 581 bp exon 136 bp exon 136 bp exon 80 bp [gt-ag] intron 80 GenBank accessions 44998 RNA-seq supporting reads 1984 UHR pooled cells 14029 Brain 352 Blood 28172 Neuroblastoma 461 Other (also 24 Primates bodymap) 522 bp exon 522 bp exon 3085 bp [gt-ag] intron 4 GenBank accessions 1119 RNA-seq supporting reads 10 UHR pooled cells 637 Brain 1 Blood 462 Neuroblastoma 9 Other 101 bp exon 615 bp [gt-ag] intron 63 GenBank accessions 29359 RNA-seq supporting reads 1501 UHR pooled cells 9241 Brain 334 Blood 17920 Neuroblastoma 363 Other (also 4661 Primates bodymap) 4 accessions, some from brain (seen 2 times) 45 bp exon Alternative mRNAs are shown aligned from 5' to 3' on a virtual genome where introns have been shrunk to a minimal length. Exon size is proportional to length, intron height reflects the number of cDNAs supporting each intron, the small numbers show the support of the introns in deep sequencing (with details in mouse-over) . Introns of the same color are identical, of different colors are different. 'Good proteins' are pink, partial or not-good proteins are yellow, uORFs are green. 5' cap or3' poly A flags show completeness of the transcript.
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Sequences: click on the numbers to get the DNA back to top
mRNA variant mRNA matching the genome Best predicted protein 5' UTR 3' UTR uORF Upstream sequence Transcription
unit
pre-mRNA		 Downstream sequence
aAug10 1213 bp 220 aa 152 bp 398 bp 2kb including Promoter 5865 bp 1kb
bAug10 1297 bp 212 aa 657 bp 2kb 6319 bp 1kb
cAug10 1452 bp 192 aa 470 bp 403 bp 432 bp 2kb including Promoter 5750 bp 1kb
dAug10 596 bp 172 aa 32 bp 75 bp 2kb probably including promoter 4618 bp 1kb
eAug10 1022 bp 155 aa 7 bp 547 bp 2kb including Promoter 1102 bp 1kb
fAug10 1573 bp 152 aa 464 bp 650 bp 39 bp 2kb possibly including promoter 6476 bp 1kb
gAug10 745 bp 138 aa 67 bp 261 bp 2kb possibly including promoter 5125 bp 1kb
hAug10 550 bp 131 aa 23 bp 131 bp 2kb including Promoter 4762 bp 1kb
iAug10 499 bp 131 aa 102 bp 2kb including Promoter 2592 bp 1kb
jAug10 783 bp 129 aa 198 bp 195 bp 2kb possibly including promoter 1294 bp 1kb
kAug10-unspliced 581 bp 115 aa 217 bp 16 bp 267 bp 2kb including Promoter 581 bp 1kb
lAug10-unspliced 570 bp 112 aa 233 bp 105 bp 2kb including Promoter 570 bp 1kb
mAug10 194 bp 63 aa 2kb probably including promoter 291 bp 1kb
nAug10 804 bp 152 aa 26 bp 343 bp 2kb probably including promoter 4584 bp 1kb
oAug10-unspliced 781 bp 78 aa 160 bp 384 bp 2kb 781 bp 1kb

Gene neighbors and Navigator on chromosome 22q11.21|22q11 back to top
FLJ41941 R PEX26andTUBA8 D C I R P USP18 D C I R P C R C G C G C R DGCR6 D C R P C C C C DGCR5 D C R P DGCR9 P DGCR10 P G TSSK1A C R P TSSK2 D C I P R R RPL34P35 C C R R G C R C R C R P GGT3P G R C G C D C R P PRODH D C I R P DGCR2andDGCR11 R D C I R P DGCR14 D C I P GSC2 D C I R P SLC25A1 D C I R P CLTCL1 D C I R P C22orf39andHIRA 100kb 0 FLJ41941, 4 accessions 2 variants PEX26andTUBA8, 311 accessions 20 variants USP18, 134 accessions 6 variants chorjey, 12 accessions 5 variants bapo, 1 accession LOC386610, 34 accessions LOC727983, 55 accessions perfaw, 76 accessions 4 variants DGCR6, 157 accessions 15 variants verdoy, 7 accessions, 2 variants snofa, 8 accessions sneyfa, 4 accessions yoyora, 10 accessions DGCR5, 84 accessions, 14 variants DGCR9, 21 accessions DGCR10, 6 accessions LOC100129262, 8 accessions TSSK1A, 6 accessions, 2 variants TSSK2, 1 accession sasoy, 15 accessions, 2 variants veydoy, 3 accessions weydoy, 1 accession pajey, 2 accessions flarfa, 1 accession flawfa, 2 accessions flawtee, 1 accession bleypy, 2 accessions fleypy, 1 accession florpy, 2 accessions glapy, 1 accession glupy, 1 accession glarpy, 2 accessions pojey, 1 accession smorvar, 4 accessions glawpy, 2 accessions soyoru, 3 accessions narser, 3 accessions torser, 2 accessions plerpy, 3 accessions snavar, 15 accessions floytee, 9 accessions shyser, 1 accession teejey, 1 accession veejey, 1 accession hisu, 1 accession verjey, 2 accessions chujey, 2 accessions blerser, 1 accession meepo, 1 accession chawfee, 1 accession chyjaw, 2 accessions barpar, 1 accession kawjoy, 1 accession sosu, 1 accession nuheru, 2 accessions, 2 variants husu, 1 accession niheru, 5 accessions skafa, 1 accession slypy, 1 accession choyjey, 1 accession dorpar, 3 accessions beepar, 17 accessions gapar, 1 accession nawsubo, 2 accessions smarpy, 2 accessions skeepy, 1 accession sharsey, 1 accession fleejey, 2 accessions stupu, 4 accessions snarvar, 1 accession snafa, 2 accessions snawfa, 2 accessions snorfa, 1 accession spupy, 1 accession speepy, 1 accession lysor, 1 accession mayora, 2 accessions, 2 variants stopy, 1 accession glojey, 1 accession doter, 2 accessions tasor, 7 accessions stawpy, 1 accession stoypy, 1 accession sayora, 1 accession ployjey, 1 accession flysor, 1 accession skarjey, 1 accession beepu, 1 accession dapu, 1 accession deypu, 1 accession slawjey, 2 accessions smojey, 1 accession rersubo, 1 accession forpu, 2 accessions suyora, 3 accessions smawjey, 2 accessions jerpu, 1 accession steefa, 1 accession skawtee, 2 accessions cheysoy, 1 accession reysubo, 2 accessions speysoy, 3 accessions rimara, 2 accessions, 2 variants swyfa, 1 accession kawpu, 1 accession smeejey, 1 accession swarfa, 1 accession moypu, 1 accession terta, 1 accession stawjey, 1 accession skeytee, 1 accession wyta, 1 accession papu, 4 accessions glyta, 1 accession pypu, 1 accession steejey, 2 accessions speevar, 1 accession pawpu, 1 accession peepu, 2 accessions borfy, 1 accession blapy, 1 accession blypy, 4 accessions blopy, 1 accession norjey, 1 accession blarpy, 1 accession blawpy, 1 accession reesubo, 2 accessions blerpy, 2 accessions fleetee, 1 accession flupy, 1 accession yayo, 3 accessions flawpy, 2 accessions fleepy, 1 accession pyjey, 1 accession flertee, 2 accessions glypy, 1 accession klorsee, 1 accession reejey, 1 accession smarsee, 1 accession sojey, 1 accession sarjey, 1 accession gleepy, 5 accessions slerfaw, 1 accession steysee, 1 accession glawfa, 1 accession klerpy, 1 accession kloypy, 1 accession gleyfa, 1 accession pleypy, 1 accession plorpy, 1 accession meebo, 4 accessions klafa, 1 accession ploypy, 2 accessions glutee, 1 accession skarpy, 1 accession heso, 1 accession moso, 1 accession mojoy, 1 accession bupar, 1 accession yuyora, 1 accession lapo, 1 accession kleyfa, 1 accession gorvy, 29 accessions pawsey, 1 accession deyvaw, 1 accession dopar, 1 accession darpar, 1 accession porka, 1 accession smofa, 1 accession smawfa, 1 accession smeyfaw, 10 accessions 3 variants koso, 1 accession smopy, 2 accessions neeka, 1 accession skeysey, 2 accessions smorpy, 2 accessions snawpy, 1 accession flyjey, 1 accession geesor, 1 accession sneypy, 1 accession spypy, 2 accessions spopy, 1 accession fleyjey, 1 accession lorsor, 1 accession swawwybo, 3 accessions gorpo, 1 accession spyfa, 9 accessions steypy, 2 accessions storpy, 2 accessions plujey, 2 accessions spofa, 3 accessions swapy, 1 accession spoyfa, 1 accession sweepy, 2 accessions swerpy, 1 accession spavar, 1 accession sweypy, 2 accessions florsor, 1 accession bypu, 1 accession swosor, 1 accession skerjey, 1 accession darpu, 1 accession slujey, 1 accession stufa, 1 accession fypu, 1 accession ploytee, 1 accession geypu, 1 accession garbo, 4 accessions spafaw, 2 accessions marsoy, 1 accession vusoy, 1 accession kypu, 7 accessions rorsubo, 1 accession meybo, 8 accessions karpu, 1 accession sparfaw, 2 accessions steesoy, 1 accession roysubo, 1 accession kata, 1 accession RPL34P35, 1 accession muta, 2 accessions snoyjey, 1 accession neypu, 2 accessions stojey, 1 accession vota, 1 accession verta, 1 accession sperfaw, 1 accession sweyfa, 1 accession worta, 2 accessions noheru, 4 accessions zyta, 2 accessions berfy, 1 accession starfaw, 4 accessions parpu, 1 accession daty, 2 accessions darty, 1 accession lerty, 1 accession syty, 1 accession voyty, 1 accession MICAL3, 513 accessions 34 variants fleytee, 2 accessions rujey, 2 accessions kayoru, 13 accessions 2 variants veedoy, 3 accessions LOC642633, 16 accessions 8 variants tasubo, 3 accessions dawtee, 2 accessions GGT3P, 48 accessions, 11 variants LOC100133163, 43 accessions 3 variants smoyfa, 2 accessions LOC653135, 1 accession PRODH, 137 accessions 14 variants DGCR2andDGCR11, 614 accessions 16 variants skatee, 2 accessions DGCR14, 362 accessions 9 variants GSC2, 2 accessions SLC25A1, 567 accessions 13 variants CLTCL1, 183 accessions 19 variants C22orf39andHIRA, 476 accessions 25 variants ZOOM IN                D:disease,C:conserved,I:interactions,R:regulation,P:publications         Read more...
Annotated mRNA diagrams back to top
Bibliography:               9 articles in PubMed back to top
? Gene Summary Gene on genome mRNA:.a, .b, .c, .d, .e, .f, .g, .h, .i, .j, .k-u, .l-u, .m, .n, .o-u Alternative mRNAs features, proteins, introns, exons, sequences Expression Tissue Function, regulation, related genes DC

To mine knowledge about the gene, please click the 'Gene Summary' or the 'Function, regulation, related genes ' tab at the top of the page. The 'Gene Summary' page includes all we learnt about the gene, functional annotations of neighboring genes, maps, links to other sites and the bibliography. The 'Function, regulation, related genes ' page includes Diseases (D), Pathways, GO annotations, conserved domains (C), interactions (I) reference into function, and pointers to all genes with the same functional annotation.
To compare alternative variants, their summarized annotations, predicted proteins, introns and exons, or to access any sequence, click the 'Alternative mRNAs features' tab. To see a specific mRNA variant diagram, sequence and annotation, click the variant name in the 'mRNA' tab. To examine expression data from all cDNAs clustered in this gene by AceView, click the 'Expression tissue'.

If you know more about this gene, or found errors, please share your knowledge. Thank you !