Homo sapiens complex locus C9orf117, encoding chromosome 9 open reading frame 117.
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SUMMARY back to top
RefSeq annotates one representative transcript (NM included in AceView variant.a), but Homo sapiens cDNA sequences in GenBank, dbEST, Trace and SRA, filtered against clone rearrangements, coaligned on the genome and clustered in a minimal non-redundant way by the manually supervised AceView program, support at least 7 spliced variants.

AceView synopsis, each blue text links to tables and details
Note that this locus is complex: it appears to produce several proteins with no sequence overlap.
Expression: According to AceView, this gene is moderately expressed, only 38.8% of the average gene in this release. The sequence of this gene is defined by 45 GenBank accessions from 36 cDNA clones, some from uterus (seen 10 times), lung (9), human lung epithelial cells (4), well-differentiated endometrialadenocarcinoma, 7 pooled tumors (4), corpus callosum (2), serous papillary carcinoma, high grade, 2pooled tumors (2), testis (2) and 11 other tissues. We annotate structural defects or features in 10 cDNA clones.
Alternative mRNA variants and regulation: The gene contains 16 distinct gt-ag introns. Transcription produces 8 different mRNAs, 7 alternatively spliced variants and 1 unspliced form. There are 3 probable alternative promotors, 3 non overlapping alternative last exons and 6 validated alternative polyadenylation sites (see the diagram). The mRNAs appear to differ by truncation of the 5' end, truncation of the 3' end, presence or absence of a cassette exon, overlapping exons with different boundaries, splicing versus retention of 4 introns. 1976 bp of this gene are antisense to spliced gene PTRH1, raising the possibility of regulated alternate expression.
2 variants were isolated in vivo, despite the fact that they are predicted targets of nonsense mediated mRNA decay (NMD).
Proteins are expected to localize in various compartments (mitochondrion, nucleus). No phenotype has yet been reported to our knowledge: this gene's in vivo function is yet unknown.
Protein coding potential: 7 spliced mRNAs putatively encode good proteins, altogether 7 different isoforms (5 complete, 2 COOH complete), some containing a second peroximal domain, a coiled coil stretch [Psort2]. The remaining mRNA variant (unspliced; partial) appears not to encode a good protein.

Please quote: AceView: a comprehensive cDNA-supported gene and transcripts annotation, Genome Biology 2006, 7(Suppl 1):S12.
Map on chromosome 9, links to other databases and other names
Map: This gene C9orf117 maps on chromosome 9, at 9q34.11 according to Entrez Gene. In AceView, it covers 9.02 kb, from 130469268 to 130478286 (NCBI 37, August 2010), on the direct strand.
Links to: the SNP view, gene overviews from Entrez Gene 286207, GeneCards, expression data from ECgene, UniGene, molecular and other annotations from UCSC, or our GOLD analysis.
The previous AceView annotation is here.
Other names: The gene is also known as C9orf117 or RP11-56D16.5, LOC286207. It has been described as hypothetical protein LOC286207.
Closest AceView homologs in other species ?
The closest mouse gene, according to BlastP, is the AceView gene 1700019L03Rik (e= 10-122).
The closest C.elegans gene, according to BlastP, is the AceView/WormGene XE304 (e=0.12).
The closest A.thaliana gene, according to BlastP, is the AceView gene AT5G58750 (e=0.95)
RNA_seq discoveries back to top
Expression/conservation in primates tissues evaluated by cross-mapping to human. back to top
C9orf117 Gene expression in 15 primates, 16 tissues, from the NHPRTR project in sFPKM BAB SkeletalMuscle WholeBlood CHP Kidney Liver Lung Spleen CMC CMM Cerebellum HUM Brain Colon Heart LymphNode Ovary Testis JMI BoneMarrow MLM OWL PTM RMC RMI Pituitary SQM Thymus MST SMY RTL 0.32 4.39 0.27 0.78 0.72 0.36 1.91 0.83 6.65 0.59 1.02 7.13 4.39 0.78 4.39 0.11 0.15 0.13 0.26 0.51 1.91 0.96 0.14 1.02 0.16 0.32 0.39 0.16 0.17 0.59 0.12 0.29 1.02 0.36 0.15 3.57 0.22 0.15 0.32 7.13 0.12 0.14 0.29 0.14 0.09 0.15 1.91 0.14 0.89 0.14 5.79 0.10 0.48 0.83 7.64 0.16 0.51 1.02 0.11 0.12 0.48 0.13 0.19 0.68 0.12 6.65 0.10 0.12 0.14 0.19 0.13 0.36 0.07 0.55 0.06 0.09 0.13 0.08 0.39 7.64 0.59 0.22 2.05 0.39 0.08 1.66 0.26 0.63 0.14 0.29 0.12 0.17 0.24 0.27 17.6 Expression quantiles None Weak 1 2 3 4 5 6 7 8 10 20 This gene All genes log2 distributions RNA-seq gene expression profile across 16 selected tissues from the Non-Human Primates Reference Transcriptome Resource (link to NHPRTR project).
- Primates: Apes (HUM: Human (Illumina BodyMap 2), CHP: Chimpanzee), Old World monkeys (PTM: Pig-Tailed Macaque, JMI Japanese Macaque, RMI Rhesus Macaque Indian, RMC Rhesus Macaque Chinese, CMM Cynomolgus Macaque Mauritian, CMC Cynomolgus Macaque Chinese, BAB Olive Baboon, SMY Sooty Mangabey); New World monkeys (MST common Marmoset, SQM Squirrel Monkey, OWL Owl Monkey); and Lemurs (MLM Mouse Lemur, RTL Ring-Tailed Lemur).
- The level for significantly expressed genes is color coded in 8 equal sized bins (light to dark green). Light gray is for weak not-accurately measured expression (2 to 8 reads above intergenic background); dark gray for no expression or no sequence conservation (0 read in gene). The plot to the right shows the distribution of measured expression values in all tissues for all genes (blue) and for this gene (green), in Magic index = log2(1000 sFPKM).
You may also examine the strand-specific genome coverage plots on the experimental AceView/Magic hub at UCSC, by tissue or by species. Tracks may be slow to load; please reload if some tracks come up yellow-greenish, and thanks to UCSC for the great work!.
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          Complete gene on genome diagram: back to top
Please choose between the zoomable GIF version., and the HTML5/SVG version.
This diagram shows in true scale the gene on the genome, the mRNAs and the cDNA clones.
Compact gene diagram back to top
Gene C9orf117 5' 3' encoded on plus strand of chromosome 9 from 130,469,268 to 130,478,286 437 132 554 505 77 209 88 a [NM] 437 132 554 505 8 209 88 b 209 23 c 437 8 g 554 505 93 d 437 26 554 505 209 1 e h-u 137 f 1 2kb 0 204 bp exon 204 bp exon 2229 bp [gt-ag] intron 9 GenBank accessions 428 RNA-seq supporting reads 11 UHR pooled cells 125 Brain 285 Neuroblastoma 7 Other (also 197 Primates bodymap) 272 bp exon 907 bp [gt-ag] intron 5 GenBank accessions 127 RNA-seq supporting reads 5 UHR pooled cells 61 Brain 61 Neuroblastoma (also 139 Primates bodymap) 154 bp exon 474 bp [gt-ag] intron 5 GenBank accessions 549 RNA-seq supporting reads 31 UHR pooled cells 187 Brain 327 Neuroblastoma 4 Other (also 160 Primates bodymap) 268 bp exon 323 bp [gt-ag] intron 5 GenBank accessions 500 RNA-seq supporting reads 8 UHR pooled cells 177 Brain 1 Blood 311 Neuroblastoma 3 Other (also 166 Primates bodymap) 131 bp exon 248 bp [gt-ag] intron 2 GenBank accessions 60 RNA-seq supporting reads 1 UHR pooled cells 30 Brain 29 Neuroblastoma (also 13 Primates bodymap) 151 bp exon 359 bp [gt-ag] intron 1 GenBank accession 76 RNA-seq supporting reads 8 UHR pooled cells 26 Brain 42 Neuroblastoma (also 31 Primates bodymap) 167 bp exon 144 bp [gt-ag] intron 6 GenBank accessions 203 RNA-seq supporting reads 8 UHR pooled cells 57 Brain 131 Neuroblastoma 7 Other (also 74 Primates bodymap) 187 bp exon 627 bp [gt-ag] intron 6 GenBank accessions 82 RNA-seq supporting reads 2 UHR pooled cells 33 Brain 46 Neuroblastoma 1 Other (also 80 Primates bodymap) 192 bp exon 8 accessions, NM_001012502.2 some from uterus (seen 2 times) hippocampus (once), human lung epithelial cells (once) lung (once), serous papillary carcinoma high grade, 2pooled tumors (once) capped 5' end, 3 accessions Validated 3' end, 2 accessions 192 bp exon 174 bp exon 174 bp exon 2229 bp [gt-ag] intron 9 GenBank accessions 428 RNA-seq supporting reads 11 UHR pooled cells 125 Brain 285 Neuroblastoma 7 Other (also 197 Primates bodymap) 272 bp exon 907 bp [gt-ag] intron 5 GenBank accessions 127 RNA-seq supporting reads 5 UHR pooled cells 61 Brain 61 Neuroblastoma (also 139 Primates bodymap) 154 bp exon 474 bp [gt-ag] intron 5 GenBank accessions 549 RNA-seq supporting reads 31 UHR pooled cells 187 Brain 327 Neuroblastoma 4 Other (also 160 Primates bodymap) 268 bp exon 323 bp [gt-ag] intron 5 GenBank accessions 500 RNA-seq supporting reads 8 UHR pooled cells 177 Brain 1 Blood 311 Neuroblastoma 3 Other (also 166 Primates bodymap) 131 bp exon 248 bp [gt-ag] intron 2 GenBank accessions 60 RNA-seq supporting reads 1 UHR pooled cells 30 Brain 29 Neuroblastoma (also 13 Primates bodymap) 151 bp exon 255 bp [gt-ag] intron 1 GenBank accession 7 RNA-seq supporting reads 4 Brain 3 Neuroblastoma 271 bp exon 271 bp exon 144 bp [gt-ag] intron 6 GenBank accessions 203 RNA-seq supporting reads 8 UHR pooled cells 57 Brain 131 Neuroblastoma 7 Other (also 74 Primates bodymap) 187 bp exon 627 bp [gt-ag] intron 6 GenBank accessions 82 RNA-seq supporting reads 2 UHR pooled cells 33 Brain 46 Neuroblastoma 1 Other (also 80 Primates bodymap) 1 accession from donated clones novartis FGA collection Validated 3' end, 1 accession 191 bp exon 138 bp exon 138 bp exon 144 bp [gt-ag] intron 6 GenBank accessions 203 RNA-seq supporting reads 8 UHR pooled cells 57 Brain 131 Neuroblastoma 7 Other (also 74 Primates bodymap) 187 bp exon 2047 bp [gt-ag] intron 1 GenBank accession 22 RNA-seq supporting reads 11 Brain 11 Neuroblastoma (also 10 Primates bodymap) 749 bp exon 14 accessions, some from lung (seen 6 times) uterus (5), well-differentiated endometrialadenocarcinoma 7 pooled tumors (3), human lung epithelial cells (2) lung normal (once) Validated 3' end, 2 accessions 749 bp exon 204 bp exon 204 bp exon 2229 bp [gt-ag] intron 9 GenBank accessions 428 RNA-seq supporting reads 11 UHR pooled cells 125 Brain 285 Neuroblastoma 7 Other (also 197 Primates bodymap) 272 bp exon 854 bp [gt-ag] intron 1 GenBank accession 7 RNA-seq supporting reads 6 Neuroblastoma 1 Other (also 1 Primates bodymap) 38 bp exon 1 accession from testis capped 5' end, 1 accession 38 bp exon 55 bp exon 55 bp exon 48 bp uORF 474 bp [gt-ag] intron 5 GenBank accessions 549 RNA-seq supporting reads 31 UHR pooled cells 187 Brain 327 Neuroblastoma 4 Other (also 160 Primates bodymap) 48 bp uORF 268 bp exon 268 bp exon 323 bp [gt-ag] intron 5 GenBank accessions 500 RNA-seq supporting reads 8 UHR pooled cells 177 Brain 1 Blood 311 Neuroblastoma 3 Other (also 166 Primates bodymap) 1056 bp exon 1056 bp exon 1056 bp exon 2378 bp [gt-ag] intron 5 GenBank accessions 88 RNA-seq supporting reads 1 UHR pooled cells 17 Brain 70 Neuroblastoma (also 4 Primates bodymap) 749 bp exon 749 bp exon 7 accessions, some from uterus (seen 2 times) brain, cerebellum, PCR rescued clones (once) capped 5' end, 1 accession Validated 3' end, 2 accessions 749 bp exon 204 bp exon 204 bp exon 453 bp uORF 2229 bp [gt-ag] intron 9 GenBank accessions 428 RNA-seq supporting reads 11 UHR pooled cells 125 Brain 285 Neuroblastoma 7 Other (also 197 Primates bodymap) 272 bp exon 453 bp uORF 272 bp exon 987 bp [gt-ag] intron 2 GenBank accessions 24 RNA-seq supporting reads 8 Brain 16 Neuroblastoma (also 1 Primates bodymap) 453 bp uORF 74 bp exon 74 bp exon 474 bp [gt-ag] intron 5 GenBank accessions 549 RNA-seq supporting reads 31 UHR pooled cells 187 Brain 327 Neuroblastoma 4 Other (also 160 Primates bodymap) 268 bp exon 268 bp exon 323 bp [gt-ag] intron 5 GenBank accessions 500 RNA-seq supporting reads 8 UHR pooled cells 177 Brain 1 Blood 311 Neuroblastoma 3 Other (also 166 Primates bodymap) 111 bp exon 111 bp exon 268 bp [gt-ag] intron 1 GenBank accession 25 RNA-seq supporting reads 9 Brain 16 Neuroblastoma 677 bp exon 677 bp exon 677 bp exon 144 bp [gt-ag] intron 6 GenBank accessions 203 RNA-seq supporting reads 8 UHR pooled cells 57 Brain 131 Neuroblastoma 7 Other (also 74 Primates bodymap) 187 bp exon 234 bp [gt-ag] intron 1 GenBank accession 3 accessions, some from corpus callosum (seen 2 times) uterus (once), well-differentiated endometrialadenocarcinoma 7 pooled tumors (once) capped 5' end, 1 accession Validated 3' end, 1 accession 581 bp exon 646 bp exon 2 accessions, some from lung (seen once) primary lung epithelial cells (once) 646 bp exon 539 bp exon 958 bp [gt-ag] intron 3 GenBank accessions 134 RNA-seq supporting reads 5 UHR pooled cells 56 Brain 71 Neuroblastoma 2 Other (also 10 Primates bodymap) 2169 bp exon 5 accessions, some from amygdala (seen once) brain (once), medulla (once) Validated 3' end, 1 accession 2169 bp exon Alternative mRNAs are shown aligned from 5' to 3' on a virtual genome where introns have been shrunk to a minimal length. Exon size is proportional to length, intron height reflects the number of cDNAs supporting each intron, the small numbers show the support of the introns in deep sequencing (with details in mouse-over) . Introns of the same color are identical, of different colors are different. 'Good proteins' are pink, partial or not-good proteins are yellow, uORFs are green. 5' cap or3' poly A flags show completeness of the transcript.
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Sequences: click on the numbers to get the DNA back to top
mRNA variant mRNA matching the genome Best predicted protein 5' UTR 3' UTR uORF Upstream sequence Transcription
unit
pre-mRNA
Downstream sequence
aAug10 1726 bp 520 aa 43 bp 120 bp 2kb including Promoter 7037 bp 1kb
bAug10 1799 bp 425 aa 13 bp 508 bp 2kb probably including promoter 7006 bp 1kb
cAug10 1074 bp 279 aa 233 bp 2kb 3265 bp 1kb
dAug10 2128 bp 211 aa 1259 bp 233 bp 45 bp 2kb including Promoter 5303 bp 1kb
eAug10 2374 bp 204 aa 392 bp 1367 bp 450 bp 2kb including Promoter 7033 bp 1kb
fAug10 2708 bp 186 aa 2147 bp 2kb 3666 bp 1kb
gAug10 514 bp 148 aa 43 bp 24 bp 2kb including Promoter 3597 bp 1kb
hAug10-unspliced 646 bp 78 aa 409 bp 2kb 646 bp 1kb

Gene neighbors and Navigator on chromosome 9q34.11 back to top
GARNL3 D C R P SLC2A8 C R P ZNF79 D C R P LRSAM1 C I R P C STXBP1 D C I R P C9orf117 C R TTC16 C R P CDK9 D C I R P FPGS D C R P R R C R SLC25A25 C R P C G R LCN2 D C I R P C9orf16 I R P R C I R P RPL12andSNORA65 C I R P FAM129B C R P PTRH1 C R C R P TOR2A C I R P SH2D3C D C I R P ENG D C I R P ST6GALNAC6andAK1 C R P ST6GALNAC4 C I R P PIP5KL1 C I R P DPM2 C R P FAM102A D C R P NAIF1 R G R D C I R P PTGES2 D C I R P CIZ1 100kb 0 RALGPS1, 278 accessions 16 variants GARNL3, 255 accessions 23 variants SLC2A8, 160 accessions 15 variants ZNF79, 79 accessions, 8 variants LRSAM1, 299 accessions 17 variants popleybu, 1 accession STXBP1, 280 accessions 15 variants C9orf117, 43 accessions 8 variants TTC16, 62 accessions, 9 variants CDK9, 236 accessions, 5 variants FPGS, 354 accessions, 20 variants wyler, 27 accessions, 2 variants kutera, 12 accessions 4 variants meetabu, 1 accession satabu, 54 accessions 3 variants SLC25A25, 247 accessions 11 variants kleeplabu, 18 accessions LOC389791, 10 accessions LCN2, 392 accessions, 10 variants C9orf16, 182 accessions 5 variants sweysoybu, 2 accessions vytyby, 1 accession beetabu, 1 accession votyby, 1 accession narpleybu, 1 accession vartyby, 1 accession vawtyby, 2 accessions veetyby, 1 accession vertyby, 3 accessions sawsher, 3 accessions hihamu, 4 accessions, 2 variants vortyby, 1 accession voytyby, 1 accession watyby, 1 accession nawpleybu, 1 accession tawler, 6 accessions deetabu, 1 accession wawtyby, 1 accession sterswaw, 1 accession weetyby, 1 accession weytyby, 1 accession zatyby, 2 accessions zytyby, 2 accessions seesher, 12 accessions fotabu, 1 accession gartabu, 1 accession zutyby, 1 accession zawtyby, 1 accession zertyby, 5 accessions zoytyby, 1 accession chatyby, 1 accession sersher, 2 accessions noypleybu, 4 accessions chytyby, 2 accessions jawtabu, 2 accessions parpleybu, 2 accessions chartyby, 1 accession kartabu, 1 accession cheytyby, 2 accessions chortyby, 1 accession lytabu, 2 accessions shatyby, 1 accession shutyby, 1 accession valer, 5 accessions shotyby, 1 accession shawtyby, 1 accession sheytyby, 1 accession gyswee, 1 accession shortyby, 1 accession guswee, 1 accession blytyby, 1 accession lotabu, 1 accession blartyby, 2 accessions blawtyby, 2 accessions perpleybu, 2 accessions skawvoby, 1 accession bleetyby, 2 accessions lartabu, 1 accession varler, 2 accessions flotyby, 1 accession flawtyby, 1 accession rypleybu, 2 accessions fleetyby, 2 accessions fleytyby, 1 accession flortyby, 1 accession floytyby, 1 accession glatyby, 2 accessions glytyby, 1 accession rupleybu, 1 accession jorswee, 1 accession snervoby, 3 accessions gleytyby, 1 accession martabu, 1 accession rekoro, 1 accession monoybu, 2 accessions hohamu, 2 accessions, 2 variants meeswee, 2 accessions noswee, 1 accession rerpleybu, 2 accessions skorsyby, 11 accessions skawtawbo, 7 accessions klawtyby, 1 accession kleetyby, 5 accessions rokoro, 1 accession rorpleybu, 1 accession sypleybu, 1 accession partabu, 1 accession tusher, 1 accession sherteebo, 1 accession puswee, 1 accession parswee, 1 accession sawpleybu, 1 accession reyswee, 1 accession sotabu, 2 accessions royswee, 1 accession sawtabu, 1 accession tatabu, 1 accession pleytyby, 1 accession plortyby, 1 accession seypleybu, 1 accession totabu, 1 accession skutyby, 1 accession skertyby, 2 accessions skortyby, 1 accession tapleybu, 1 accession slutyby, 11 accessions slartyby, 2 accessions koyvarby, 2 accessions slawtyby, 5 accessions sleytyby, 2 accessions mito_carr.18, 1 accession teyswee, 1 accession vertabu, 1 accession smotyby, 2 accessions voytabu, 1 accession smawtyby, 1 accession sosher, 5 accessions batabu, 12 accessions bartabu, 1 accession vutyby, 1 accession dytabu, 1 accession stuswaw, 1 accession dartabu, 1 accession wytyby, 2 accessions wutyby, 1 accession neepleybu, 1 accession wortyby, 2 accessions steyswaw, 1 accession deytabu, 1 accession derswee, 1 accession geytabu, 1 accession zartyby, 19 accessions zeytyby, 4 accessions zortyby, 1 accession norpleybu, 1 accession pypleybu, 2 accessions huhamu, 2 accessions, 2 variants chutyby, 1 accession hehamu, 1 accession pawpleybu, 1 accession jertabu, 1 accession chawtyby, 1 accession jortabu, 1 accession cheetyby, 1 accession chertyby, 1 accession hosuro, 1 accession choytyby, 3 accessions shytyby, 1 accession lutabu, 3 accessions sorsher, 2 accessions shartyby, 1 accession nomure, 1 accession vyler, 1 accession sheetyby, 1 accession shertyby, 1 accession blatyby, 3 accessions blutyby, 1 accession blotyby, 4 accessions bleytyby, 1 accession bloytyby, 1 accession skeevoby, 5 accessions leetabu, 2 accessions sharteebo, 1 accession leytabu, 1 accession flutyby, 1 accession klawplabu, 2 accessions rapleybu, 1 accession flertyby, 1 accession glutyby, 1 accession lortabu, 1 accession loytabu, 1 accession kuswee, 2 accessions rikoro, 2 accessions gloytyby, 1 accession rukoro, 1 accession klutyby, 5 accessions shawteebo, 1 accession rawpleybu, 1 accession mawtabu, 2 accessions reepleybu, 1 accession waler, 2 accessions paswee, 1 accession beyvarby, 2 accessions notabu, 1 accession nortabu, 1 accession borvarby, 1 accession pawtabu, 1 accession klortyby, 5 accessions platyby, 1 accession plytyby, 1 accession plutyby, 3 accessions neygar, 2 accessions sarpleybu, 1 accession reeswee, 1 accession roytabu, 3 accessions plertyby, 1 accession serpleybu, 2 accessions ploytyby, 1 accession skatyby, 2 accessions skytyby, 1 accession votabu, 1 accession juvarby, 6 accessions skartyby, 1 accession skeetyby, 2 accessions vartabu, 1 accession skeytyby, 1 accession vawtabu, 1 accession skoytyby, 1 accession kuvarby, 7 accessions weeler, 1 accession slytyby, 2 accessions slotyby, 1 accession slertyby, 1 accession slortyby, 2 accessions sarswee, 1 accession veetabu, 1 accession soyswee, 1 accession tupleybu, 2 accessions smytyby, 1 accession yukoro, 1 accession smeetyby, 1 accession smertyby, 1 accession toler, 2 accessions dornoybu, 1 accession RPL12andSNORA65, 475 accessions 15 variants FAM129B, 432 accessions 8 variants PTRH1, 141 accessions 12 variants glawtyby, 2 accessions vawler, 4 accessions TOR2A, 183 accessions 10 variants SH2D3C, 426 accessions 27 variants ENG, 464 accessions, 16 variants ST6GALNAC6andAK1, 690 accessions 30 variants ST6GALNAC4, 256 accessions 4 variants PIP5KL1, 45 accessions 15 variants DPM2, 328 accessions, 6 variants FAM102A, 266 accessions 10 variants NAIF1, 146 accessions 7 variants peygar, 3 accessions LOC100289019, 33 accessions 5 variants PTGES2, 476 accessions 18 variants CIZ1, 536 accessions, 26 variants ZOOM IN                D:disease,C:conserved,I:interactions,R:regulation,P:publications         Read more...
Annotated mRNA diagrams back to top
? Gene Summary Gene on genome mRNA:.a, .b, .c, .d, .e, .f, .g, .h-u Alternative mRNAs features, proteins, introns, exons, sequences Expression Tissue Function, regulation, related genes C

To mine knowledge about the gene, please click the 'Gene Summary' or the 'Function, regulation, related genes ' tab at the top of the page. The 'Gene Summary' page includes all we learnt about the gene, functional annotations of neighboring genes, maps, links to other sites and the bibliography. The 'Function, regulation, related genes ' page includes Diseases (D), Pathways, GO annotations, conserved domains (C), interactions (I) reference into function, and pointers to all genes with the same functional annotation.
To compare alternative variants, their summarized annotations, predicted proteins, introns and exons, or to access any sequence, click the 'Alternative mRNAs features' tab. To see a specific mRNA variant diagram, sequence and annotation, click the variant name in the 'mRNA' tab. To examine expression data from all cDNAs clustered in this gene by AceView, click the 'Expression tissue'.

If you know more about this gene, or found errors, please share your knowledge. Thank you !