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Gene WRNTABLE OF CONTENTS / OPEN CLOSE ALL PARAGRAPHS
Summary back to top
Compact gene diagram back to top
82 supporting clones for gene WRN back to top
cDNA accession
Links to the sequence
Tissue

most 5' clones
in red
Match
mRNA
From bp
to bp
in mRNA
From bp
to bp
in accs.
Clone encodes
complete protein
(with AA variation)
Features Anomalies
detected by
AceView
Accession
match over
(% length)
Base differences
relative to genome
(% identity)
AF091214   WRN.a 1 to 4752 437 to 5188 L1005F tiling clone, AAA Possibly primed on the genome, locally A rich (24/26 A in genome downstream of last aligned base) 4752/5188
(91 %)
3 diff
(100.0 %id)
AY818673   WRN.a 1 to 4094 206 to 4299 L1005F     4094/4299
(95 %)
3 diff
(100.0 %id)
NM_000553.4   WRN.a 1 to 4752 994 to 5745 exact RefSeq, AAA Possibly primed on the genome, locally A rich (24/26 A in genome downstream of last aligned base) 4752/5745
(82 %)
0 diff
(100 %id)
EH319287   WRN.a 194 to 264 1 to 71       71/71
(100 %)
0 diff
(100 %id)
T39125   WRN.a 400 to 839 1 to 440       440/441
(99 %)
2 diff
(99.6 %id)
AL707510 human skeletal muscle WRN.a 502 to 1127 1 to 626       626/626
(100 %)
5 diff
(99.3 %id)
CF137269 lymph WRN.a 1010 to 1447 8 to 444       437/451
(96 %)
8 diff
(98.3 %id)
TI_154166690   WRN.a 1010 to 1613 80 to 683       604/850
(71 %)
21 diff
(97.6 %id)
BM552381 leiomyosarcoma, uterus WRN.a 1074 to 1985 1 to 920       920/1026
(89 %)
18 diff
(98.3 %id)
DA119116 cerebellum WRN.a 1215 to 1758 2 to 548   capped   545/547
(99 %)
3 diff
(99.5 %id)
BG714322 brain, hypothalamus WRN.a 1220 to 1935 1 to 719       719/719
(100 %)
9 diff
(98.8 %id)
DB636601 hypothalamus WRN.a 1225 to 1898 1 to 674       674/674
(100 %)
0 diff
(100 %id)
BP282255 bone marrow WRN.a 1281 to 1869 1 to 589       589/589
(100 %)
1 diff
(99.9 %id)
DB090798 testis WRN.a 1375 to 1947 2 to 574   capped   573/573
(100 %)
0 diff
(100 %id)
AB209652 Spleen WRN.a 1565 to 4494 1 to 2930   tiling clone,   2930/2930
(100 %)
2 diff
(100.0 %id)
EH350242   WRN.a 1935 to 2001 1 to 67       67/67
(100 %)
2 diff
(97.1 %id)
DA002795   WRN.a 2305 to 2864 2 to 561   capped   560/560
(100 %)
0 diff
(100 %id)
AA373157 lung WRN.a 2384 to 2690 1 to 307       307/307
(100 %)
1 diff
(99.7 %id)
BP357289 mammary gland WRN.a 2453 to 3028 1 to 577       577/583
(98 %)
4 diff
(99.4 %id)
BQ305407 breast WRN.a 2479 to 2969 1 to 488       488/489
(99 %)
14 diff
(97.2 %id)
BQ305613 breast WRN.a 2480 to 2965 6 to 491       486/491
(98 %)
4 diff
(99.2 %id)
DA829362 placenta WRN.a 2563 to 3263 2 to 712   capped   709/733
(96 %)
15 diff
(98.0 %id)
AW965099   WRN.a 2739 to 3462 1 to 727       727/728
(99 %)
12 diff
(98.4 %id)
AA344201 gall bladder WRN.a 2759 to 3096 1 to 339       339/339
(100 %)
2 diff
(99.5 %id)
R58879   WRN.a 2789 to 3028 1 to 240       240/245
(97 %)
2 diff
(99.2 %id)
AL709832 human skeletal muscle WRN.a 2833 to 3532 1 to 698       702/698
(100 %)
9 diff
(98.8 %id)
W40393 Pancreas, pancreatic islet WRN.a 2845 to 3193 1 to 352       352/352
(100 %)
5 diff
(98.6 %id)
EC470365 Prostate WRN.a 3180 to 3275 1 to 94       94/94
(100 %)
2 diff
(97.9 %id)
BG992948 head_neck WRN.a 3441 to 3891 450 to 1       450/450
(100 %)
4 diff
(99.2 %id)
CR997591 T-Lymphocytes WRN.a 3513 to 4411 1 to 899       899/899
(100 %)
1 diff
(99.9 %id)
BF103840 embryonal carcinoma, testis WRN.a 3645 to 4363 1 to 712       712/864
(82 %)
20 diff
(97.7 %id)
BU633322 cell lines, Chondrosarcoma WRN.a 3718 to 4403 701 to 19   AAA Possibly primed on the genome, locally A rich (24/26 A in genome downstream of last aligned base) 683/683
(100 %)
4 diff
(99.5 %id)
CB156864 Liver WRN.a 3775 to 4306 9 to 540       532/540
(98 %)
0 diff
(100 %id)
AA193296 mixed (see below), Pooled human melanocyte, fetal heart, andpregnant uterus WRN.a 3785 to 4364 1 to 585       585/587
(99 %)
12 diff
(98.0 %id)
AA193286 mixed (see below), Pooled human melanocyte, fetal heart, andpregnant uterus WRN.a 3786 to 4359 1 to 579       579/584
(99 %)
13 diff
(97.8 %id)
BM721721 eye, fetal eye WRN.a 3810 to 4295 1 to 486     Possibly primed on the genome, locally A rich (24/26 A in genome downstream of last aligned base) 486/486
(100 %)
0 diff
(100 %id)
AI203498   WRN.a 3918 to 4399 481 to 1       481/481
(100 %)
1 diff
(99.8 %id)
AA835784 germinal center B cell WRN.a 3936 to 4395 495 to 35   AAA Possibly primed on the genome, locally A rich (24/26 A in genome downstream of last aligned base) 461/461
(100 %)
4 diff
(99.2 %id)
AI025669   WRN.a 3943 to 4399 456 to 1       456/458
(99 %)
6 diff
(98.7 %id)
N64051 cochlea, ear WRN.a 3958 to 4344 400 to 13   AAA Possibly primed on the genome, locally A rich (24/26 A in genome downstream of last aligned base) 388/388
(100 %)
1 diff
(99.8 %id)
DB374151 placenta WRN.a 4303 to 4746 446 to 2       445/463
(96 %)
0 diff
(100 %id)
BM677308 eye, fetal eye WRN.a 4386 to 4746 379 to 19   AAA Possibly primed on the genome, locally A rich (24/26 A in genome downstream of last aligned base) 361/361
(100 %)
1 diff
(99.8 %id)
AL833572 human endometrium WRN.b 1 to 3593 1 to 3593 L541F L775R tiling clone, available from DKFZ, AAA Possibly primed on the genome, locally A rich (24/26 A in genome downstream of last aligned base) 3593/3593
(100 %)
5 diff
(99.9 %id)
BX489680   WRN.b 1 to 638 1 to 638       638/638
(100 %)
3 diff
(99.6 %id)
AA287985 germinal center B cell WRN.b 1927 to 2257 1 to 330       330/330
(100 %)
1 diff
(99.7 %id)
AI457716 pooled WRN.b 2826 to 3236 438 to 25       414/438
(94 %)
0 diff
(100 %id)
BE787985 large cell carcinoma, lung WRN.b 2830 to 3284 1 to 462   tiling clone,   462/938
(49 %)
16 diff
(98.3 %id)
DB561219 hypothalamus WRN.b 2871 to 3585 1 to 706     Submitted on the opposite strand 706/706
(100 %)
12 diff
(98.4 %id)
BQ774611 Bone, Human Chondrosarcoma Cell Line WRN.b 2883 to 3585 720 to 19   AAA Possibly primed on the genome, locally A rich (24/26 A in genome downstream of last aligned base) 702/702
(100 %)
2 diff
(99.8 %id)
CN425423 embryonic stem cells, cell lines H1, H7, andH9 WRN.b 2887 to 3411 1 to 526       526/526
(100 %)
1 diff
(99.9 %id)
BE932661 head_neck WRN.b 2977 to 3476 504 to 5       500/504
(99 %)
8 diff
(98.5 %id)
AA359610 lung WRN.b 3103 to 3432 1 to 331       331/331
(100 %)
4 diff
(98.8 %id)
AW959698   WRN.b 3104 to 3742 1 to 639       639/639
(100 %)
7 diff
(99.0 %id)
AA287923 germinal center B cell WRN.b 3132 to 3587 462 to 7       456/462
(98 %)
0 diff
(100 %id)
DA543021   WRN.b 3203 to 3772 2 to 571   capped   570/570
(100 %)
0 diff
(100 %id)
AI277125 adenocarcinoma, colon WRN.b 3273 to 3587 315 to 1       315/315
(100 %)
0 diff
(100 %id)
AI280329 placenta WRN.b 3289 to 3592 312 to 9       304/312
(97 %)
0 diff
(100 %id)
BP293902 lung WRN.b 3334 to 3915 1 to 582       582/582
(100 %)
1 diff
(99.9 %id)
BP294058 lung WRN.b 3334 to 3914 1 to 581       581/582
(99 %)
2 diff
(99.7 %id)
BM471189 melanotic melanoma, skin WRN.b 3341 to 4346 1 to 1004   tiling clone,   1004/1013
(99 %)
25 diff
(97.6 %id)
AA249288   WRN.b 3417 to 3846 1 to 430       430/432
(99 %)
11 diff
(97.5 %id)
CB216263 normal endometrium, mid-secretory phase,cycle day 23, uterus WRN.b 4066 to 4624 1 to 559   tiling clone,   559/570
(98 %)
1 diff
(99.9 %id)
AA430122   WRN.b 4138 to 4408 274 to 4       271/274
(98 %)
0 diff
(100 %id)
AW811688 stomach WRN.b 4314 to 4616 306 to 5       302/306
(98 %)
0 diff
(100 %id)
CD654107 Embryonic Stem cells WRN.c 1 to 710 1 to 701   tiling clone,   701/811
(86 %)
12 diff
(98.6 %id)
CD657076 Embryonic Stem cells WRN.c 259 to 1016 8 to 760       753/796
(94 %)
4 diff
(99.5 %id)
CD723639 eye, lacrimal gland WRN.c 507 to 1135 1 to 629 exact tiling clone,   629/629
(100 %)
1 diff
(99.9 %id)
FN078119 breast carcinoma WRN.d 1 to 87 8 to 94 T2Q tiling clone,   87/95
(91 %)
3 diff
(96.9 %id)
BP349077 brain WRN.d 1 to 582 1 to 583   tiling clone,   583/583
(100 %)
5 diff
(99.2 %id)
BP279291   WRN.d 62 to 643 1 to 582       582/582
(100 %)
0 diff
(100 %id)
BM785803 Ascites, stomach WRN.d 318 to 867 1 to 550   tiling clone,   550/550
(100 %)
1 diff
(99.9 %id)
CR737800 liver and spleen WRN.e-u 1 to 775 1 to 778 exact tiling clone,   778/780
(99 %)
5 diff
(99.4 %id)
H80461 liver and spleen WRN.e-u 1 to 371 12 to 382 exact     371/382
(97 %)
0 diff
(100 %id)
N54899 liver and spleen WRN.e-u 861 to 1335 480 to 1   tiling clone,   480/482
(99 %)
8 diff
(98.4 %id)
AI023450 liver and spleen WRN.e-u 940 to 1335 396 to 1   tiling clone,   396/396
(100 %)
2 diff
(99.5 %id)
H81381 liver and spleen WRN.e-u 956 to 1329 381 to 1       381/391
(97 %)
13 diff
(96.7 %id)
TI_149295590   WRN.f-u 1 to 753 861 to 112 N40* tiling clone, AAA   750/860
(87 %)
16 diff
(98.2 %id)
BU683758 lung, Primary Lung Cystic Fibrosis EpithelialCells WRN.f-u 132 to 753 636 to 14 N40* tiling clone, AAA   623/625
(99 %)
3 diff
(99.6 %id)
AW016548   WRN.g-u 1 to 359 377 to 18 exact tiling clone, AAA Possibly primed on the genome, locally A rich (24/26 A in genome downstream of last aligned base) 360/360
(100 %)
4 diff
(98.9 %id)
BQ354585 head_neck WRN.g-u 65 to 400 1 to 345 I3H N4E K5Y A6S D7* tiling clone,   345/345
(100 %)
26 diff
(92.5 %id)
BG941850 blood WRN.h-u 1 to 390 1 to 390 exact tiling clone,   390/390
(100 %)
3 diff
(99.3 %id)
DW432831 Liver WRN.i 1 to 232 18 to 249 A11E D20E L22* tiling clone, AAA   232/249
(93 %)
19 diff
(92.4 %id)
DW443800 Liver Gene WRN, variant not shown         This clone was ignored    
R05311 liver and spleen Gene WRN, variant not shown         This clone was ignored    
R05371 liver and spleen Gene WRN, variant not shown         This clone was ignored    
AA778924 liver and spleen Gene WRN, variant not shown         This clone was ignored    
DB211560 trachea Gene WRN, variant not shown       capped This clone was ignored    
DB348787 trachea Gene WRN, variant not shown         This clone was ignored    
? Gene Summary Gene on genome mRNA:.a, .b, .c, .d, .e-u, .f-u, .g-u, .h-u, .i Alternative mRNAs features, proteins, introns, exons, sequences Expression Tissue Function, regulation, related genes DCI