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Gene SMOTABLE OF CONTENTS / OPEN CLOSE ALL PARAGRAPHS
Summary back to top
Compact gene diagram back to top
128 supporting clones for gene SMO back to top
cDNA accession
Links to the sequence
Tissue

most 5' clones
in red
Match
mRNA
From bp
to bp
in mRNA
From bp
to bp
in accs.
Clone encodes
complete protein
(with AA variation)
Features Anomalies
detected by
AceView
Accession
match over
(% length)
Base differences
relative to genome
(% identity)
CN396922 embryonic stem cells, embryoid bodiesderived from H1, H7 and H9 cells .a 1 to 422 1 to 422   tiling clone,   422/422
(100 %)
2 diff
(99.6 %id)
BY797478 eye .a 22 to 419 1 to 398       398/398
(100 %)
0 diff
(100 %id)
CN396918 embryonic stem cells, DMSO-treated H9 cellline .a 25 to 419 1 to 395       395/395
(100 %)
2 diff
(99.5 %id)
CN396920 embryonic stem cells, cell lines H1, H7, andH9 .a 78 to 226 1 to 149       149/149
(100 %)
1 diff
(99.4 %id)
CN396915 embryonic stem cells, embryoid bodiesderived from H1, H7 and H9 cells .a 222 to 665 1 to 444       444/444
(100 %)
2 diff
(99.6 %id)
BF311110 brain, neuroblastoma .a 226 to 1029 1 to 786       786/899
(87 %)
44 diff
(95.2 %id)
BC009989 Brain, neuroblastoma .a 227 to 3961 1 to 3735 exact tiling clone, available from MGC, AAA   3735/3735
(100 %)
3 diff
(100.0 %id)
NM_005631.4   .a 227 to 3961 1 to 3735 exact RefSeq, AAA   3735/3735
(100 %)
1 diff
(100.0 %id)
CN396923 embryonic stem cells, cell lines H1, H7, andH9 .a 258 to 776 1 to 519       519/519
(100 %)
2 diff
(99.7 %id)
AW614083 Kidney .a 281 to 409 129 to 1       129/129
(100 %)
0 diff
(100 %id)
AF120103   .a 449 to 3961 1 to 3513 exact AAA   3513/3513
(100 %)
3 diff
(100.0 %id)
AI081895 mixed (see below), Pooled human melanocyte, fetal heart, andpregnant uterus .a 449 to 945 1 to 497     Submitted on the opposite strand 497/497
(100 %)
0 diff
(100 %id)
CN396914 embryonic stem cells, cell lines H1, H7, andH9 .a 468 to 752 1 to 285       285/285
(100 %)
1 diff
(99.7 %id)
AW195468 Kidney .a 487 to 1234 1 to 731     Submitted on the opposite strand 731/734
(99 %)
13 diff
(98.3 %id)
AF071494   .a 507 to 3961 1 to 3455 exact AAA   3455/3455
(100 %)
3 diff
(100.0 %id)
U84401   .a 507 to 2870 1 to 2364 exact     2364/2364
(100 %)
1 diff
(100.0 %id)
BE244950 leukopheresis .a 608 to 722 1 to 115       115/115
(100 %)
5 diff
(95.7 %id)
BF924794 nervous_tumor .a 731 to 892 1 to 162       162/165
(98 %)
4 diff
(97.6 %id)
AA070532   .a 842 to 1227 1 to 395       395/396
(99 %)
16 diff
(96.0 %id)
BU845864 ovary, teratocarcinoma, cell line .a 908 to 1654 1 to 749       749/922
(81 %)
8 diff
(99.2 %id)
BM557532 duodenal adenocarcinoma, cell line, small intestine .a 1238 to 2052 1 to 821       821/1003
(81 %)
12 diff
(98.9 %id)
CN396913 embryonic stem cells, cell lines H1, H7, andH9 .a 1240 to 1874 1 to 634       634/634
(100 %)
3 diff
(99.6 %id)
DB253589 uterus .a 1259 to 1732 2 to 475   capped   474/474
(100 %)
3 diff
(99.4 %id)
DA926570 small intestine .a 1286 to 1807 2 to 523   capped   522/522
(100 %)
1 diff
(99.9 %id)
AU129944   .a 1290 to 1844 2 to 556   tiling clone, capped   555/555
(100 %)
4 diff
(99.3 %id)
CD620952   .a 1344 to 1958 7 to 621       615/621
(99 %)
8 diff
(98.8 %id)
CD620953   .a 1414 to 2093 693 to 14       680/693
(98 %)
2 diff
(99.8 %id)
AA298711 synovial membrane .a 1563 to 1762 1 to 200       200/200
(100 %)
1 diff
(99.5 %id)
BE393053 endometrium, adenocarcinoma cell line, uterus .a 1652 to 2121 1 to 471   available from MGC,   471/472
(99 %)
3 diff
(99.4 %id)
DA687229   .a 1671 to 2208 2 to 539   capped   538/538
(100 %)
1 diff
(99.9 %id)
DA753221   .a 1792 to 2333 2 to 543   capped   542/542
(100 %)
0 diff
(100 %id)
BU509583 leiomyosarcoma, uterus .a 1914 to 2678 1 to 772       772/929
(83 %)
14 diff
(98.5 %id)
AU125363   .a 1931 to 2680 2 to 749   capped   748/750
(99 %)
12 diff
(98.4 %id)
DA905862   .a 1966 to 2417 2 to 454   capped   453/453
(100 %)
1 diff
(99.8 %id)
AU117917 whole embryo, mainly head .a 2033 to 2813 2 to 780   capped   779/779
(100 %)
9 diff
(98.9 %id)
BP375963 uterus .a 2079 to 2665 1 to 588       588/588
(100 %)
3 diff
(99.5 %id)
BI009452 kidney_tumor .a 2152 to 2576 1 to 430       427/439
(97 %)
22 diff
(95.0 %id)
BP196155 adrenal gland .a 2154 to 2735 1 to 583       583/583
(100 %)
1 diff
(99.9 %id)
BG423960 Kidney, renal cell adenocarcinoma .a 2172 to 2576 1 to 407       407/553
(73 %)
5 diff
(99.1 %id)
BE889268 leiomyosarcoma, uterus .a 2375 to 2889 1 to 520       520/520
(100 %)
10 diff
(98.1 %id)
DB363013   .a 3403 to 3961 556 to 1       556/559
(99 %)
17 diff
(97.0 %id)
DB367219   .a 3437 to 3961 528 to 1   tiling clone,   528/536
(98 %)
10 diff
(98.2 %id)
DB355899 whole embryo, mainly head .a 3466 to 3961 495 to 1       495/495
(100 %)
11 diff
(97.8 %id)
AU132302   .b 1 to 828 2 to 830   tiling clone, capped   829/871
(95 %)
15 diff
(98.3 %id)
BC004332 Uterus, endometrium adenocarcinoma .b 118 to 2700 1 to 2583   tiling clone, available from MGC, AAA   2583/2583
(100 %)
3 diff
(99.9 %id)
BX641825   .b 1192 to 1884 1 to 693       693/693
(100 %)
0 diff
(100 %id)
DR761983 embryonic stem .b 1199 to 2023 1 to 825       825/825
(100 %)
1 diff
(99.9 %id)
CN396916 embryonic stem cells, embryoid bodiesderived from H1, H7 and H9 cells .b 1204 to 1905 1 to 702       702/702
(100 %)
0 diff
(100 %id)
CX781753 human embryonic stem cells .b 1212 to 1983 1 to 772       772/772
(100 %)
0 diff
(100 %id)
AF130867 synovial membrane .b 1366 to 2700 2 to 1336       1335/1336
(99 %)
7 diff
(99.5 %id)
AA377764 synovial membrane .b 1404 to 1683 1 to 280       280/280
(100 %)
1 diff
(99.7 %id)
CX788788 human embryonic stem cells .b 1475 to 2278 1 to 804       804/804
(100 %)
3 diff
(99.7 %id)
BM725012 eye, fetal eye .b 1568 to 2167 1 to 599   fully sequenced,   599/599
(100 %)
0 diff
(100 %id)
BG898783 cartilage .b 1576 to 1903 86 to 413       328/345
(95 %)
10 diff
(97.2 %id)
BE742716 adenocarcinoma cell line, ovary .b 1590 to 2411 1 to 832       832/976
(85 %)
34 diff
(96.6 %id)
BE785546 large cell carcinoma, lung .b 1590 to 2234 1 to 645       645/645
(100 %)
2 diff
(99.7 %id)
BE740072 adenocarcinoma cell line, ovary .b 1592 to 2441 1 to 845       845/1079
(78 %)
27 diff
(97.5 %id)
BM020600 astrocytoma grade IV, cell line, brain .b 1598 to 2418 1 to 822       822/824
(99 %)
18 diff
(97.9 %id)
TI_59388218   .b 1599 to 2418 106 to 926       821/823
(99 %)
18 diff
(97.9 %id)
BM714878 eye, fetal eyes, lens, eye anterior segment,optic nerve, retina, Retina Foveal and Macular, RPE andChoroid .b 1600 to 2261 1 to 662       662/662
(100 %)
1 diff
(99.9 %id)
BP251446 hippocampus .b 1648 to 2229 1 to 582   tiling clone,   582/584
(99 %)
1 diff
(99.9 %id)
BM689270 eye, optic nerve .b 1676 to 2238 4 to 565       562/565
(99 %)
6 diff
(99.0 %id)
BG033244 breast, mammary adenocarcinoma, cell line .b 1735 to 2459 1 to 718       718/721
(99 %)
14 diff
(98.1 %id)
AI751900 Bone, Hip .b 1751 to 2063 8 to 320       313/320
(97 %)
0 diff
(100 %id)
BM695194 eye, optic nerve .b 1821 to 2498 1 to 677       677/677
(100 %)
3 diff
(99.6 %id)
CN396924 embryonic stem cells, DMSO-treated H9 cellline .b 1838 to 2324 1 to 487       487/487
(100 %)
3 diff
(99.4 %id)
BE440077 Trabecular meshwork .b 1860 to 2472 1 to 610       610/612
(99 %)
6 diff
(99.1 %id)
TI_151699280   .b 1898 to 2704 888 to 98   AAA   791/916
(86 %)
15 diff
(98.4 %id)
TI_154052513   .b 1915 to 2700 864 to 85   AAA   780/957
(81 %)
15 diff
(98.5 %id)
BI047368 prostate_tumor .b 1928 to 2200 1 to 271       271/283
(95 %)
14 diff
(95.1 %id)
D81673 brain .b 1951 to 2271 1 to 321       321/321
(100 %)
3 diff
(99.1 %id)
AF089720   .b 1975 to 2700 1 to 727       727/727
(100 %)
8 diff
(98.9 %id)
TI_154097858   .b 1975 to 2700 810 to 86   AAA   725/813
(89 %)
11 diff
(98.7 %id)
N88486   .b 1982 to 2256 1 to 275       275/275
(100 %)
1 diff
(99.7 %id)
BF031231 hypernephroma, Kidney .b 1996 to 2571 1 to 564       564/830
(67 %)
19 diff
(97.8 %id)
BQ019170 lung, Metastatic Chondrosarcoma .b 2009 to 2700 709 to 17   AAA   693/693
(100 %)
7 diff
(99.0 %id)
BQ009350 Chondrosarcoma, Left Pubic Bone .b 2012 to 2700 705 to 17   AAA   689/689
(100 %)
4 diff
(99.5 %id)
CA445076 lung, Metastatic Chondrosarcoma .b 2030 to 2700 688 to 17   AAA   672/672
(100 %)
3 diff
(99.6 %id)
BQ016281 lung, Metastatic Chondrosarcoma .b 2039 to 2700 681 to 19   AAA   663/663
(100 %)
6 diff
(99.1 %id)
BQ774327 Chondrosarcoma Grade II, Left Pelvis .b 2073 to 2700 647 to 19   AAA   629/629
(100 %)
3 diff
(99.6 %id)
CA440778 lung, Metastatic Chondrosarcoma .b 2074 to 2700 645 to 17   AAA   629/629
(100 %)
4 diff
(99.4 %id)
TI_159708431   .b 2078 to 2700 720 to 97   AAA   624/1041
(59 %)
7 diff
(99.4 %id)
R71695 breast .b 2082 to 2412 1 to 336   fully sequenced,   336/336
(100 %)
3 diff
(99.2 %id)
BX101123 breast .b 2084 to 2700 1 to 617   AAA   617/617
(100 %)
2 diff
(99.7 %id)
TI_149312364   .b 2088 to 2700 699 to 91   AAA   609/896
(67 %)
12 diff
(98.7 %id)
G43672   .b 2091 to 2239 1 to 150       150/150
(100 %)
2 diff
(98.7 %id)
H26675 breast .b 2091 to 2501 1 to 421     Submitted on the opposite strand 421/476
(88 %)
20 diff
(95.8 %id)
H61259 ovarian tumor, ovary .b 2106 to 2579 1 to 481       481/483
(99 %)
15 diff
(96.9 %id)
BM977867 lung .b 2116 to 2700 600 to 17   AAA   584/587
(99 %)
5 diff
(99.2 %id)
BM680230 eye, fetal eye .b 2137 to 2700 582 to 18   fully sequenced, AAA   565/565
(100 %)
2 diff
(99.7 %id)
CA415268 Knee, Osteoarthritic Cartilage .b 2160 to 2700 554 to 17   AAA   538/538
(100 %)
3 diff
(99.5 %id)
AI820024 lung, squamous cell carcinoma, poorlydifferentiated (4 pooled tumors, including primary andmetastatic) .b 2165 to 2700 536 to 1       536/536
(100 %)
2 diff
(99.7 %id)
DB369318   .b 2167 to 2704 535 to 1       535/560
(95 %)
12 diff
(97.9 %id)
BQ013075 placenta .b 2169 to 2700 548 to 17   AAA   532/532
(100 %)
4 diff
(99.3 %id)
TI_153990196   .b 2170 to 2700 641 to 109   AAA   533/536
(99 %)
19 diff
(96.5 %id)
AA448522   .b 2180 to 2484 1 to 305       305/305
(100 %)
3 diff
(99.1 %id)
AW172939 moderately-differentiated endometrialadenocarcinoma, 3 pooled tumors, uterus .b 2196 to 2704 509 to 1       509/509
(100 %)
6 diff
(98.9 %id)
CN396921 embryonic stem cell, retinoic acid andmitogen-treated hES cell line H7 .b 2203 to 2601 1 to 399   tiling clone,   399/399
(100 %)
2 diff
(99.5 %id)
H61263.
matches multiple genes
ovarian tumor, ovary .b 2232 to 2684 456 to 1     also hits gene EIF2C4 456/456
(100 %)
9 diff
(98.1 %id)
AA738463 pooled germ cell tumors .b 2234 to 2700 480 to 14   AAA   467/467
(100 %)
3 diff
(99.4 %id)
AI127817 uterus .b 2237 to 2704 466 to 1   tiling clone,   466/466
(100 %)
5 diff
(99.0 %id)
AA070437   .b 2238 to 2700 464 to 1       464/464
(100 %)
2 diff
(99.6 %id)
BM725308 eye, fetal eyes, lens, eye anterior segment,optic nerve, retina, Retina Foveal and Macular, RPE andChoroid .b 2239 to 2703 1 to 465       465/467
(99 %)
2 diff
(99.6 %id)
AI422943 brain, glioblastoma (pooled) .b 2267 to 2698 432 to 1       432/432
(100 %)
1 diff
(99.8 %id)
AI056937 brain, glioblastoma (pooled) .b 2269 to 2703 437 to 3       435/437
(99 %)
0 diff
(100 %id)
BM691014 eye, RPE and Choroid .b 2275 to 2700 21 to 446   fully sequenced, AAA   426/446
(95 %)
0 diff
(100 %id)
AI885759 anaplastic oligodendroglioma, brain .b 2289 to 2704 422 to 7       416/422
(98 %)
0 diff
(100 %id)
AI870408 anaplastic oligodendroglioma, brain .b 2289 to 2704 422 to 7       416/422
(98 %)
0 diff
(100 %id)
W86576 liver and spleen .b 2292 to 2698 408 to 1       408/408
(100 %)
3 diff
(99.3 %id)
AA524933   .b 2298 to 2702 35 to 438       404/460
(87 %)
7 diff
(98.5 %id)
BF109726 pooled .b 2310 to 2700 391 to 1       391/391
(100 %)
3 diff
(99.3 %id)
AI812047 uterus, well-differentiated endometrialadenocarcinoma, 7 pooled tumors .b 2313 to 2700 421 to 34   AAA   388/392
(98 %)
11 diff
(97.2 %id)
BU726335 eye, RPE and Choroid .b 2323 to 2700 395 to 18   fully sequenced, AAA   378/378
(100 %)
1 diff
(99.8 %id)
BU727390 eye, optic nerve .b 2325 to 2700 394 to 19   AAA   376/376
(100 %)
3 diff
(99.3 %id)
D60699   .b 2339 to 2700 361 to 1       361/361
(100 %)
2 diff
(99.5 %id)
AI140041 heart .b 2343 to 2701 359 to 1       359/359
(100 %)
2 diff
(99.5 %id)
AI264951 borderline ovarian carcinoma, ovary .b 2343 to 2700 368 to 11   AAA   358/358
(100 %)
1 diff
(99.8 %id)
AI870486 anaplastic oligodendroglioma, brain .b 2343 to 2700 369 to 12   AAA   358/358
(100 %)
4 diff
(98.9 %id)
AW206150   .b 2355 to 2700 361 to 16   AAA   346/346
(100 %)
1 diff
(99.8 %id)
AI160552 uterus .b 2364 to 2702 342 to 4       339/342
(99 %)
0 diff
(100 %id)
R71663 breast .b 2382 to 2672 296 to 1   fully sequenced,   296/296
(100 %)
1 diff
(99.7 %id)
BM675390 eye, fetal eyes, lens, eye anterior segment,optic nerve, retina, Retina Foveal and Macular, RPE andChoroid .b 2392 to 2701 326 to 19   AAA   308/308
(100 %)
3 diff
(99.1 %id)
BU861150 mixed (pool of 40 RNAs) .b 2397 to 2704 1 to 308       308/345
(89 %)
1 diff
(99.8 %id)
AI807682 pooled .b 2418 to 2703 286 to 1       286/286
(100 %)
2 diff
(99.4 %id)
AW593101 pooled .b 2418 to 2697 280 to 1       280/280
(100 %)
0 diff
(100 %id)
H98971 melanocyte .b 2458 to 2700 243 to 1       243/243
(100 %)
0 diff
(100 %id)
BF342418 brain, glioblastoma with EGFR amplification .b 2471 to 2699 1 to 229   AAA   229/229
(100 %)
4 diff
(98.3 %id)
AW022584 cochlea, ear .b 2472 to 2700 1 to 229   AAA   229/229
(100 %)
4 diff
(98.3 %id)
BM141978 Islets of Langerhans, Pancreas .b 2526 to 2703 1 to 178       178/219
(81 %)
1 diff
(99.6 %id)
DB163340 thymus .c 1 to 552 2 to 553 exact tiling clone, capped   552/552
(100 %)
0 diff
(100 %id)
CN396917 embryonic stem cells, cell lines H1, H7, andH9 .d 1 to 732 1 to 729 K4R T5P S6P Y7T F8S ... tiling clone,   729/729
(100 %)
6 diff
(99.2 %id)
AI401179 B-cell, chronic lymphotic leukemia .d 557 to 919 422 to 59   tiling clone, AAA   364/392
(92 %)
0 diff
(100 %id)
AU117827 whole embryo, mainly head .e 1 to 778 3 to 774 exact tiling clone, capped   772/805
(95 %)
12 diff
(98.6 %id)
BP232611 muscle .e 583 to 1164 1 to 583   tiling clone,   583/583
(100 %)
1 diff
(99.9 %id)
R21016 whole brain .e 708 to 1066 1 to 368       368/371
(99 %)
19 diff
(94.9 %id)
DB355767 whole embryo, mainly head .e 1996 to 2554 559 to 1   tiling clone,   559/562
(99 %)
13 diff
(97.7 %id)
AI809418 pooled Gene SMO, variant not shown         Suspected internal deletion, this clone was ignored    
BE784306 eye, retinoblastoma Gene SMO, variant not shown         This clone was ignored    
? Gene Summary Gene on genome mRNA:.a, .b, .c, .d, .e Alternative mRNAs features, proteins, introns, exons, sequences Expression Tissue Function, regulation, related genes DCI