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Gene RAD51TABLE OF CONTENTS / OPEN CLOSE ALL PARAGRAPHS
Summary back to top
Compact gene diagram back to top
168 supporting clones for gene RAD51 back to top
cDNA accession
Links to the sequence
Tissue

most 5' clones
in red
Match
mRNA
From bp
to bp
in mRNA
From bp
to bp
in accs.
Clone encodes
complete protein
(with AA variation)
Features Anomalies
detected by
AceView
Accession
match over
(% length)
Base differences
relative to genome
(% identity)
NM_133487.3   .a 1 to 2302 1 to 2302 exact RefSeq,   2302/2302
(100 %)
0 diff
(100 %id)
AK291969   .a 46 to 1560 1 to 1515 exact tiling clone,   1515/1515
(100 %)
0 diff
(100 %id)
DA914687   .a 47 to 615 2 to 570   capped   569/569
(100 %)
0 diff
(100 %id)
AI347079 adenocarcinoma, colon .a 640 to 1501 864 to 1       862/883
(97 %)
19 diff
(97.9 %id)
BQ278437 mixed (pool of 40 RNAs) .a 663 to 1469 1 to 814       814/898
(90 %)
24 diff
(97.4 %id)
BG774318 choriocarcinoma, placenta .a 667 to 1480 1 to 808       808/813
(99 %)
14 diff
(98.3 %id)
BG480368 choriocarcinoma, placenta .a 670 to 1312 1 to 650       650/651
(99 %)
14 diff
(97.9 %id)
BQ918872 carcinoma, cell line, Prostate .a 704 to 1542 26 to 873       848/956
(88 %)
35 diff
(96.4 %id)
BX349297   .a 744 to 1674 1 to 924       924/929
(99 %)
21 diff
(97.8 %id)
BU624430 cell lines, Enchondroma .a 816 to 1517 719 to 19   AAA   701/701
(100 %)
2 diff
(99.8 %id)
CN414128 embryonic stem cell, retinoic acid andmitogen-treated hES cell line H7 .a 890 to 1699 1 to 812       812/812
(100 %)
2 diff
(99.8 %id)
BE394150 endometrium, adenocarcinoma cell line, uterus .a 936 to 1497 1 to 559       559/560
(99 %)
6 diff
(99.0 %id)
AW363521 colon .a 937 to 1139 1 to 203       203/203
(100 %)
0 diff
(100 %id)
AW363520 colon .a 944 to 1144 8 to 208       201/208
(96 %)
4 diff
(98.1 %id)
CR626167 Neuroblastoma Cot 25-normalized .a 946 to 1737 1 to 792   tiling clone,   792/792
(100 %)
0 diff
(100 %id)
AL526670 brain, neuroblastoma cells, Neuroblastoma Cot 25-normalized .a 946 to 1198 1 to 253   fully sequenced,   253/253
(100 %)
1 diff
(99.7 %id)
TI_154130710   .a 947 to 1737 889 to 104   AAA   786/890
(88 %)
10 diff
(98.9 %id)
BE186007 head_neck .a 1025 to 1394 32 to 402       369/402
(91 %)
10 diff
(97.6 %id)
BE926933 breast .a 1025 to 1394 32 to 402       369/402
(91 %)
10 diff
(97.6 %id)
AL526641 brain, neuroblastoma cells, Neuroblastoma Cot 25-normalized .a 1168 to 1708 541 to 1   fully sequenced,   541/541
(100 %)
10 diff
(98.2 %id)
DA592536 lung .b 1 to 557 2 to 558   tiling clone, capped   557/557
(100 %)
0 diff
(100 %id)
AA167733   .b 21 to 468 446 to 1       446/446
(100 %)
2 diff
(99.6 %id)
DA092107 cerebellum .b 222 to 785 2 to 565   tiling clone, capped   564/564
(100 %)
1 diff
(99.9 %id)
AK131299   .b 636 to 2217 1 to 1582 exact tiling clone, available from FLJ,   1582/1582
(100 %)
0 diff
(100 %id)
NM_001164269.1   .b 636 to 2782 1 to 2147 exact RefSeq,   2147/2147
(100 %)
0 diff
(100 %id)
DA610707   .b 637 to 1199 2 to 564   capped   563/563
(100 %)
0 diff
(100 %id)
BF764274 colon_est .b 1673 to 2068 1 to 394       394/394
(100 %)
18 diff
(95.5 %id)
AA873056 pooled germ cell tumors .b 1678 to 2151 477 to 1       477/558
(85 %)
26 diff
(95.4 %id)
AI419710 pooled .b 1690 to 2269 587 to 12   tiling clone, AAA   576/616
(93 %)
12 diff
(98.1 %id)
AW392597 stomach .b 1712 to 2080 371 to 2       370/371
(99 %)
0 diff
(100 %id)
AW006523 colon .b 1712 to 2211 518 to 19   AAA   500/500
(100 %)
2 diff
(99.6 %id)
AA568782 colon, colon tumor RER+ .b 1714 to 2267 558 to 6       553/558
(99 %)
0 diff
(100 %id)
AW103435 ovary, tumor, 5 pooled (see description) .b 1818 to 2219 404 to 3       402/404
(99 %)
0 diff
(100 %id)
TI_149286680   .b 1840 to 2780 1018 to 93   AAA   926/1142
(81 %)
54 diff
(95.3 %id)
BF683589 leiomyosarcoma cell line, uterus .b 1847 to 2217 1 to 368       368/615
(59 %)
6 diff
(99.1 %id)
FN154942 breast carcinoma .b 1888 to 1987 97 to 1     Submitted on the opposite strand 97/100
(97 %)
7 diff
(93.0 %id)
BM145097 leukopheresis .b 1917 to 2274 419 to 61       359/420
(85 %)
0 diff
(100 %id)
AI970091 pooled germ cell tumors .b 1973 to 2218 256 to 11       246/256
(96 %)
0 diff
(100 %id)
FN059816 breast carcinoma .b 2078 to 2194 1 to 117       117/117
(100 %)
0 diff
(100 %id)
BM972210 lung .b 2149 to 2780 651 to 19   tiling clone, AAA   633/633
(100 %)
3 diff
(99.6 %id)
AI670798 uterus, well-differentiated endometrialadenocarcinoma, 7 pooled tumors .b 2264 to 2963 699 to 1   tiling clone,   699/776
(90 %)
21 diff
(97.3 %id)
NM_002875.4   .c 1 to 2299 1 to 2299 exact RefSeq,   2299/2299
(100 %)
0 diff
(100 %id)
AK313503 brain .c 46 to 1319 1 to 1274 exact tiling clone,   1274/1274
(100 %)
0 diff
(100 %id)
D14134 testis .c 68 to 2297 1 to 2229 exact tiling clone,   2229/2229
(100 %)
5 diff
(99.8 %id)
CR594665 Neuroblastoma Cot 25-normalized .c 96 to 1712 1 to 1617 exact     1617/1617
(100 %)
0 diff
(100 %id)
CR622784 placenta .c 96 to 1711 1 to 1616 exact     1616/1616
(100 %)
0 diff
(100 %id)
AL524788 brain, neuroblastoma cells, Neuroblastoma Cot 25-normalized .c 96 to 948 1 to 852   fully sequenced,   852/852
(100 %)
4 diff
(99.6 %id)
AL541688 placenta .c 96 to 997 1 to 901   fully sequenced,   901/901
(100 %)
4 diff
(99.6 %id)
D13804 bone marrow .c 96 to 1733 10 to 1645 K313Q     1636/1645
(99 %)
11 diff
(99.4 %id)
CR619182 Neuroblastoma Cot 25-normalized .c 104 to 1711 1 to 1608 exact     1608/1608
(100 %)
0 diff
(100 %id)
AL526399 brain, neuroblastoma cells, Neuroblastoma Cot 25-normalized .c 104 to 901 1 to 799   fully sequenced,   799/799
(100 %)
4 diff
(99.5 %id)
BM808716 amelanotic melanoma, cell line, skin .c 119 to 1130 1 to 1026       1024/1076
(95 %)
31 diff
(97.2 %id)
BT019705   .c 300 to 1317 1 to 1018       1018/1020
(99 %)
2 diff
(99.9 %id)
CR536559   .c 300 to 1319 1 to 1020 exact     1020/1020
(100 %)
0 diff
(100 %id)
BF969466 adrenal cortex carcinoma, cell line, adrenal gland .c 509 to 1238 1 to 727       727/739
(98 %)
9 diff
(98.8 %id)
BF311612 brain, neuroblastoma .c 620 to 1345 1 to 723       723/793
(91 %)
7 diff
(99.2 %id)
BE312219 brain, neuroblastoma .c 639 to 1287 1 to 647       647/701
(92 %)
4 diff
(99.5 %id)
AL526587 brain, neuroblastoma cells, Neuroblastoma Cot 25-normalized .c 871 to 1675 842 to 39   fully sequenced, AAA   804/833
(96 %)
1 diff
(99.9 %id)
AL524787 brain, neuroblastoma cells, Neuroblastoma Cot 25-normalized .c 913 to 1626 805 to 88   fully sequenced, AAA   718/782
(91 %)
6 diff
(99.3 %id)
AL569030 placenta .c 967 to 1636 745 to 75   fully sequenced, AAA   671/726
(92 %)
7 diff
(99.1 %id)
EU362635   .d 1 to 1611 1 to 1611 exact tiling clone,   1611/1611
(100 %)
2 diff
(99.9 %id)
NM_001164270.1   .d 1 to 2177 1 to 2177 exact RefSeq,   2177/2177
(100 %)
0 diff
(100 %id)
DA711273   .d 10 to 555 2 to 550   capped   549/549
(100 %)
4 diff
(99.3 %id)
BM147841 leukopheresis .d 32 to 498 1 to 467       467/468
(99 %)
2 diff
(99.6 %id)
AU100170   .d 33 to 332 1 to 300       300/300
(100 %)
0 diff
(100 %id)
AU107551   .d 33 to 82 1 to 50       50/50
(100 %)
0 diff
(100 %id)
BM804639 lymph, lymphoma, cell line .d 37 to 822 1 to 789       789/1119
(70 %)
21 diff
(98.2 %id)
DR155931 human embryonic stem cells differentiated toan early endodermal cell type .d 41 to 754 1 to 714       714/714
(100 %)
0 diff
(100 %id)
CN481135 eye .d 42 to 658 1 to 617       617/617
(100 %)
3 diff
(99.6 %id)
BI827729 brain, medulla .d 43 to 896 1 to 865       863/871
(99 %)
20 diff
(97.8 %id)
BU596395 mixed (pool of 40 RNAs) .d 43 to 591 1 to 554       554/892
(62 %)
26 diff
(97.1 %id)
TI_57171983   .d 43 to 832 35 to 834       798/905
(88 %)
18 diff
(98.1 %id)
AU118946 whole embryo, mainly head .d 44 to 776 2 to 738   capped   735/738
(99 %)
9 diff
(98.8 %id)
BM791694 stomach .d 46 to 696 1 to 651       651/651
(100 %)
0 diff
(100 %id)
DA520304 brain .d 47 to 612 2 to 567   capped   566/566
(100 %)
0 diff
(100 %id)
DA542497 lung .d 47 to 545 2 to 500   capped   499/499
(100 %)
1 diff
(99.8 %id)
DA615018   .d 47 to 625 2 to 580   capped   579/579
(100 %)
0 diff
(100 %id)
DA706491   .d 47 to 615 2 to 571   capped   570/570
(100 %)
1 diff
(99.9 %id)
DA850420 placenta .d 47 to 589 2 to 545   capped   544/544
(100 %)
1 diff
(99.9 %id)
BM745228 stomach .d 47 to 677 1 to 631       631/631
(100 %)
2 diff
(99.7 %id)
DB051302 testis .d 47 to 609 2 to 568   capped   567/567
(100 %)
4 diff
(99.3 %id)
DB102268 thymus .d 47 to 601 2 to 557   capped   556/556
(100 %)
1 diff
(99.9 %id)
DB107132 thymus .d 47 to 615 2 to 571   capped   570/570
(100 %)
2 diff
(99.7 %id)
BF684891 leiomyosarcoma cell line, uterus .d 49 to 736 1 to 694       694/1075
(64 %)
24 diff
(97.8 %id)
BG338607 leiomyosarcoma cell line, uterus .d 49 to 734 1 to 689       687/1103
(62 %)
10 diff
(99.1 %id)
BX475478   .d 50 to 441 1 to 397       395/397
(99 %)
9 diff
(97.8 %id)
DA005315   .d 53 to 627 2 to 580   capped   579/579
(100 %)
5 diff
(99.2 %id)
AU123935   .d 53 to 615 2 to 564   capped   563/573
(98 %)
2 diff
(99.7 %id)
DA912372   .d 53 to 625 2 to 575   capped   574/574
(100 %)
2 diff
(99.7 %id)
DB025496 testis .d 53 to 611 2 to 560   capped   559/559
(100 %)
0 diff
(100 %id)
BX364160   .d 60 to 948 1 to 889       887/990
(89 %)
11 diff
(98.9 %id)
BI193363 epithelioid carcinoma cell line, Pancreas .d 62 to 614 1 to 564       479/564
(84 %)
13 diff
(97.7 %id)
BX475529   .d 63 to 516 1 to 454       454/454
(100 %)
4 diff
(99.2 %id)
BG474115 eye, retinoblastoma .d 63 to 680 1 to 618       618/622
(99 %)
1 diff
(99.9 %id)
BU164989 epithelioid carcinoma, Pancreas .d 64 to 839 1 to 778       778/831
(93 %)
13 diff
(98.5 %id)
AW732525 Kidney, renal cell adenocarcinoma .d 65 to 701 1 to 637       637/637
(100 %)
7 diff
(99.0 %id)
DN998694 bone marrow .d 68 to 790 27 to 749       723/749
(96 %)
7 diff
(99.1 %id)
BQ224221 embryonal carcinoma, cell line, testis .d 69 to 587 107 to 628       522/1096
(47 %)
35 diff
(96.9 %id)
BU508719 leiomyosarcoma, uterus .d 69 to 918 24 to 885       862/887
(97 %)
27 diff
(97.0 %id)
CN414127 embryonic stem cell, retinoic acid andmitogen-treated hES cell line H7 .d 70 to 638 1 to 569       569/569
(100 %)
0 diff
(100 %id)
BG420079 Kidney, renal cell adenocarcinoma .d 71 to 835 1 to 768       768/879
(87 %)
37 diff
(95.8 %id)
BU931527 ovary, teratocarcinoma, cell line .d 72 to 729 9 to 670       662/904
(73 %)
15 diff
(98.4 %id)
BM018810 astrocytoma grade IV, cell line, brain .d 76 to 822 1 to 755       755/941
(80 %)
22 diff
(97.7 %id)
BE262785 brain, neuroblastoma .d 78 to 907 1 to 824       824/1008
(81 %)
20 diff
(98.1 %id)
BG325079 Kidney, renal cell adenocarcinoma .d 78 to 767 1 to 688       688/688
(100 %)
4 diff
(99.5 %id)
BM910438 astrocytoma grade IV, cell line, brain .d 78 to 1066 1 to 1007       1007/1064
(94 %)
26 diff
(97.6 %id)
TI_59389479   .d 78 to 822 96 to 849       754/940
(80 %)
22 diff
(97.7 %id)
AL530472 brain, neuroblastoma cells, Neuroblastoma Cot 50-normalized .d 81 to 1070 2 to 992       991/992
(99 %)
11 diff
(98.9 %id)
AU107550   .d 83 to 132 1 to 50       50/50
(100 %)
2 diff
(96.0 %id)
BE514829 adenocarcinoma cell line, ovary .d 83 to 742 1 to 668       666/729
(91 %)
18 diff
(97.6 %id)
BU553012 ovary, teratocarcinoma, cell line .d 84 to 948 1 to 869       869/909
(95 %)
12 diff
(98.7 %id)
TI_57173261   .d 84 to 794 30 to 740       711/740
(96 %)
6 diff
(99.2 %id)
DA996531   .d 84 to 574 2 to 492   capped   491/491
(100 %)
0 diff
(100 %id)
BE256767 eye, retinoblastoma .d 87 to 839 1 to 756       756/947
(79 %)
10 diff
(99.0 %id)
BF313295 brain, neuroblastoma .d 87 to 757 1 to 682       682/683
(99 %)
20 diff
(97.1 %id)
BF313593 brain, neuroblastoma .d 87 to 793 1 to 705       705/706
(99 %)
5 diff
(99.3 %id)
BI197901 brain, neuroblastoma .d 87 to 789 1 to 725       722/768
(94 %)
39 diff
(95.0 %id)
BI826961 brain, medulla .d 87 to 794 1 to 708       708/708
(100 %)
2 diff
(99.8 %id)
BF970732 adrenal cortex carcinoma, cell line, adrenal gland .d 90 to 826 1 to 741       739/892
(82 %)
11 diff
(98.8 %id)
BQ070384 brain, neuroblastoma, cell line .d 91 to 645 1 to 560       560/1275
(43 %)
12 diff
(99.1 %id)
BQ053625 blood, natural killer cells, cell line .d 91 to 1073 1 to 989       989/991
(99 %)
20 diff
(98.0 %id)
BM011814 brain, neuroblastoma, cell line .d 98 to 763 1 to 668       668/673
(99 %)
10 diff
(98.6 %id)
TI_59380991   .d 99 to 763 100 to 766       667/672
(99 %)
9 diff
(98.7 %id)
DB022234 testis .d 99 to 652 2 to 557   capped   556/558
(99 %)
6 diff
(99.0 %id)
BF982698 duodenal adenocarcinoma, cell line, small intestine .d 100 to 832 1 to 741       741/747
(99 %)
21 diff
(97.2 %id)
CN414126 embryonic stem cells, cell lines H1, H7, andH9 .d 101 to 493 1 to 393       393/393
(100 %)
0 diff
(100 %id)
BQ424388 eye, retinoblastoma .d 101 to 981 1 to 898       798/900
(88 %)
22 diff
(97.6 %id)
BG826929 muscle, rhabdomyosarcoma .d 103 to 901 1 to 799       799/799
(100 %)
6 diff
(99.3 %id)
BQ438308 leiomyosarcoma, uterus .d 106 to 926 11 to 832   tiling clone,   822/882
(93 %)
8 diff
(99.1 %id)
CV809484 Blastocyst, pluripotent cell line derived fromblastocyst inner cell mass .d 109 to 941 1 to 835       835/880
(94 %)
25 diff
(97.2 %id)
BM557367 amelanotic melanoma, cell line, skin .d 116 to 745 28 to 656       629/1208
(52 %)
27 diff
(97.8 %id)
BM558629 amelanotic melanoma, cell line, skin .d 118 to 993 1 to 884       882/1050
(84 %)
17 diff
(98.4 %id)
BM810067 amelanotic melanoma, cell line, skin .d 119 to 1072 1 to 948       946/1173
(80 %)
27 diff
(97.7 %id)
BU182612 melanotic melanoma, skin .d 133 to 1007 1 to 879       879/881
(99 %)
15 diff
(98.3 %id)
BQ070341 brain, neuroblastoma, cell line .d 171 to 1081 1 to 918       918/1006
(91 %)
17 diff
(98.4 %id)
BE883694 leiomyosarcoma, uterus .d 231 to 951 1 to 712       712/778
(91 %)
19 diff
(97.6 %id)
BX494877 Liver .d 274 to 700 1 to 427       427/427
(100 %)
0 diff
(100 %id)
BM796675 Ascites, stomach .d 384 to 797 1 to 414       414/414
(100 %)
1 diff
(99.8 %id)
CF139164 CNCAP(3)T-225 cell line, Prostate .d 524 to 992 19 to 487       467/487
(95 %)
6 diff
(98.8 %id)
TI_154169385   .d 524 to 1011 91 to 578   tiling clone,   486/500
(97 %)
7 diff
(98.6 %id)
BQ316481 colon .d 567 to 917 1 to 353       351/353
(99 %)
6 diff
(98.4 %id)
BQ316480 colon .d 569 to 917 1 to 351       349/351
(99 %)
5 diff
(98.6 %id)
BQ316451 colon .d 637 to 917 74 to 354       281/354
(79 %)
6 diff
(98.4 %id)
AI018041   .d 945 to 1378 436 to 3       434/436
(99 %)
1 diff
(99.8 %id)
AU145391 whole embryo, mainly head .d 1071 to 1612 542 to 1       542/563
(96 %)
13 diff
(97.7 %id)
AL563755 brain, neuroblastoma cells, Neuroblastoma Cot 50-normalized .d 1210 to 2325 1116 to 1   tiling clone,   1116/1117
(99 %)
53 diff
(95.3 %id)
CK825953 Pancreas, Purified pancreatic islet .e 1 to 620 1 to 620   tiling clone,   620/620
(100 %)
4 diff
(99.4 %id)
CK825952 Pancreas, Purified pancreatic islet .e 484 to 1051 568 to 1   tiling clone,   568/568
(100 %)
0 diff
(100 %id)
DA843464 placenta .e 1037 to 1601 2 to 566   tiling clone, capped   565/565
(100 %)
0 diff
(100 %id)
BF203788 muscle, rhabdomyosarcoma .f 1 to 696 1 to 695 V15G E16G E17R E18R S19K ... tiling clone,   695/971
(71 %)
16 diff
(98.4 %id)
CR606487 Neuroblastoma Cot 50-normalized .g 1 to 1545 1 to 1545 exact tiling clone,   1545/1545
(100 %)
0 diff
(100 %id)
AL530290 brain, neuroblastoma cells, Neuroblastoma Cot 50-normalized .g 1 to 951 1 to 946 D12E L60X D72E I136X fully sequenced,   946/946
(100 %)
6 diff
(99.4 %id)
DB115748 thymus .g 498 to 949 2 to 454   capped   453/453
(100 %)
1 diff
(99.8 %id)
AL563696 brain, neuroblastoma cells, Neuroblastoma Cot 50-normalized .g 890 to 1545 655 to 1   fully sequenced,   655/655
(100 %)
18 diff
(97.3 %id)
DA817616   .h 1 to 571 2 to 573   tiling clone, capped   572/572
(100 %)
2 diff
(99.7 %id)
BG470554 eye, retinoblastoma .h 10 to 550 1 to 546       546/547
(99 %)
13 diff
(97.7 %id)
DB025014 testis .h 14 to 575 2 to 564   capped   563/563
(100 %)
1 diff
(99.9 %id)
BE890859 melanotic melanoma, skin .h 46 to 793 1 to 741       741/961
(77 %)
14 diff
(98.6 %id)
BM555611 duodenal adenocarcinoma, cell line, small intestine .h 74 to 922 1 to 858 L103P Y104L R105Q T106N D107R ... tiling clone,   858/1053
(81 %)
16 diff
(98.5 %id)
BE779265 eye, retinoblastoma .h 262 to 922 1 to 657 Q76R T77P Q78S L79S L80F ... tiling clone,   657/661
(99 %)
14 diff
(97.9 %id)
AY608888   .h 435 to 562 1 to 128       128/128
(100 %)
0 diff
(100 %id)
DC399792 testis .i 1 to 532 1 to 532   tiling clone,   532/532
(100 %)
1 diff
(99.9 %id)
DB037351 testis .i 52 to 622 2 to 572   capped   571/571
(100 %)
0 diff
(100 %id)
DB054457 testis .i 86 to 625 2 to 541   tiling clone, capped   540/540
(100 %)
0 diff
(100 %id)
AY425955 testis .i 555 to 979 1 to 425   tiling clone,   425/425
(100 %)
1 diff
(99.8 %id)
BF085986 placenta_normal .j-u 1 to 226 21 to 246 F2Q V3L K4E N5K Y6L ... tiling clone,   226/246
(91 %)
9 diff
(96.4 %id)
BF086893 placenta_normal .j-u 1 to 226 15 to 239 F2Q V3L I11L E12N L14* tiling clone,   225/239
(94 %)
6 diff
(97.5 %id)
BG001759 placenta_normal .j-u 12 to 226 15 to 226   tiling clone,   212/226
(93 %)
6 diff
(97.4 %id)
T19802   Gene RAD51, variant not shown              
BC001459 Placenta, choriocarcinoma Gene RAD51, variant not shown       available from MGC, AAA Suspected internal deletion, this clone was ignored    
DC404907 thymus Gene RAD51, variant not shown         This clone was ignored    
AK303089 thymus Gene RAD51, variant not shown         This clone was ignored    
BE280848 choriocarcinoma, placenta Gene RAD51, variant not shown         Suspected internal deletion, this clone was ignored    
BG469700 adenocarcinoma cell line, colon Gene RAD51, variant not shown         This clone was ignored    
BG774691 choriocarcinoma, placenta Gene RAD51, variant not shown         This clone was ignored    
? Gene Summary Gene on genome mRNA:.a, .b, .c, .d, .e, .f, .g, .h, .i, .j-u Alternative mRNAs features, proteins, introns, exons, sequences Expression Tissue Function, regulation, related genes DCI