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Gene POLETABLE OF CONTENTS / OPEN CLOSE ALL PARAGRAPHS
Summary back to top
Compact gene diagram back to top
421 supporting clones for gene POLE back to top
cDNA accession
Links to the sequence
Tissue

most 5' clones
in red
Match
mRNA
From bp
to bp
in mRNA
From bp
to bp
in accs.
Clone encodes
complete protein
(with AA variation)
Features Anomalies
detected by
AceView
Accession
match over
(% length)
Base differences
relative to genome
(% identity)
L09561   POLE.a 1 to 6912 1 to 6912 S2251T tiling clone,   6912/6912
(100 %)
3 diff
(100.0 %id)
NM_006231.2   POLE.a 1 to 7840 1 to 7840 exact RefSeq, AAA   7840/7840
(100 %)
0 diff
(100 %id)
U49356   POLE.a 45 to 6905 1 to 6858       6858/6858
(100 %)
7 diff
(99.9 %id)
BG981168 colon_normal POLE.a 58 to 440 385 to 2       384/387
(99 %)
4 diff
(99.0 %id)
BG981449 colon_normal POLE.a 289 to 422 147 to 8       140/147
(95 %)
5 diff
(96.6 %id)
AW300080 Kidney POLE.a 616 to 1263 649 to 1       649/655
(99 %)
23 diff
(96.5 %id)
AB209902 aorta endothelial cell POLE.a 621 to 4195 1 to 3576       3576/5067
(70 %)
3 diff
(100.0 %id)
AI660087 thymus, pooled POLE.a 680 to 1327 646 to 1       646/646
(100 %)
6 diff
(99.1 %id)
BF855348 prostate_normal POLE.a 685 to 864 6 to 184       179/184
(97 %)
6 diff
(96.8 %id)
BF115176 Kidney POLE.a 746 to 1318 573 to 1       573/573
(100 %)
0 diff
(100 %id)
AA722637 heart POLE.a 847 to 1313 469 to 1       469/510
(91 %)
15 diff
(97.1 %id)
AW450295   POLE.a 880 to 1326 447 to 1       447/457
(97 %)
0 diff
(100 %id)
AI825841 colon, colon tumor, RER+ POLE.a 930 to 1327 398 to 1       398/398
(100 %)
0 diff
(100 %id)
TI_2194644999   POLE.a 973 to 1726 17 to 770     Submitted on the opposite strand 754/801
(94 %)
25 diff
(96.9 %id)
TI_2194695952   POLE.a 989 to 2067 25 to 1093       1069/1241
(86 %)
17 diff
(98.7 %id)
AW206393   POLE.a 1138 to 1326 190 to 1       190/201
(94 %)
10 diff
(95.1 %id)
CN332488 embryonic stem cells, cell lines H1, H7, andH9 POLE.a 1152 to 1739 1 to 588       588/588
(100 %)
2 diff
(99.7 %id)
TI_2194697538   POLE.a 1182 to 2226 14 to 1054       1041/1285
(81 %)
14 diff
(99.0 %id)
CU449795 epidermis POLE.a 1260 to 1935 21 to 696       676/696
(97 %)
0 diff
(100 %id)
AA954575 pooled POLE.a 1320 to 1719 1 to 397     Submitted on the opposite strand 397/397
(100 %)
5 diff
(98.8 %id)
AI475491 pooled POLE.a 1320 to 1901 1 to 582     Submitted on the opposite strand 582/582
(100 %)
3 diff
(99.5 %id)
BF732729 fibrotheoma, ovary POLE.a 1320 to 1864 1 to 546     Submitted on the opposite strand 546/546
(100 %)
1 diff
(99.9 %id)
BF513578   POLE.a 1321 to 1820 1 to 500     Submitted on the opposite strand 500/500
(100 %)
0 diff
(100 %id)
BM452532 lymph, lymphoma, cell line POLE.a 1327 to 2070 1 to 746       746/1108
(67 %)
11 diff
(99.1 %id)
AW969126   POLE.a 1329 to 1890 1 to 562       562/642
(87 %)
8 diff
(98.8 %id)
AA905939 pooled POLE.a 1336 to 1895 14 to 566     Submitted on the opposite strand 553/566
(97 %)
16 diff
(97.2 %id)
BF593907 pooled POLE.a 1343 to 1864 1 to 522     Submitted on the opposite strand 522/523
(99 %)
1 diff
(99.9 %id)
AI243258 pooled POLE.a 1349 to 1846 1 to 496     Submitted on the opposite strand 496/554
(89 %)
9 diff
(98.4 %id)
AW001917 thymus, pooled POLE.a 1349 to 1815 1 to 467     Submitted on the opposite strand 467/467
(100 %)
1 diff
(99.8 %id)
AW104468 pooled POLE.a 1349 to 1902 1 to 555     Submitted on the opposite strand 553/558
(99 %)
22 diff
(96.1 %id)
AW197253 pooled germ cell tumors POLE.a 1354 to 1547 1 to 194     Submitted on the opposite strand 194/194
(100 %)
0 diff
(100 %id)
AW197866 pooled POLE.a 1354 to 1689 1 to 337     Submitted on the opposite strand 337/337
(100 %)
5 diff
(98.6 %id)
AW589733 pooled germ cell tumors POLE.a 1354 to 1547 1 to 194     Submitted on the opposite strand 194/194
(100 %)
0 diff
(100 %id)
AW235362 pooled germ cell tumors POLE.a 1378 to 1547 1 to 170     Submitted on the opposite strand 170/170
(100 %)
0 diff
(100 %id)
AA731003 germinal center B cell POLE.a 1403 to 1967 1 to 565     Submitted on the opposite strand 565/565
(100 %)
27 diff
(95.3 %id)
AA768650 germinal center B cell POLE.a 1403 to 1802 1 to 392     Submitted on the opposite strand 394/399
(98 %)
14 diff
(96.5 %id)
AA732394 germinal center B cell POLE.a 1423 to 1730 1 to 308     Submitted on the opposite strand 308/308
(100 %)
9 diff
(97.1 %id)
TI_2194695967   POLE.a 1471 to 2513 9 to 1049       1041/1268
(82 %)
10 diff
(99.3 %id)
BG230504 moderate to poorly differentiated invasivecarcinoma, tongue POLE.a 1626 to 2035 1 to 410       410/411
(99 %)
15 diff
(96.4 %id)
TI_2194697529   POLE.a 1639 to 2793 11 to 1156       1146/1299
(88 %)
20 diff
(98.5 %id)
BQ322268 colon_est POLE.a 1647 to 1914 17 to 285       269/285
(94 %)
6 diff
(97.9 %id)
CR984585 T-Lymphocytes POLE.a 1785 to 2537 1 to 752       752/753
(99 %)
2 diff
(99.8 %id)
BQ308864 breast POLE.a 1787 to 1993 1 to 208       208/219
(94 %)
3 diff
(98.7 %id)
AL712973 human skeletal muscle POLE.a 1917 to 2549 8 to 640       633/640
(98 %)
6 diff
(99.1 %id)
BQ324834 colon_ins POLE.a 1924 to 2304 1 to 380       380/380
(100 %)
18 diff
(95.3 %id)
BF883435 lung_tumor POLE.a 2078 to 2180 8 to 110       103/110
(93 %)
8 diff
(92.8 %id)
TI_2194697526   POLE.a 2090 to 3298 1 to 1195       1168/1281
(91 %)
23 diff
(98.3 %id)
BU183348 melanotic melanoma, skin POLE.a 2119 to 2910 1 to 795       795/912
(87 %)
10 diff
(99.0 %id)
BF155593 head_neck POLE.a 2150 to 2534 10 to 394       385/403
(95 %)
28 diff
(93.1 %id)
TI_2194695966   POLE.a 2171 to 3221 10 to 1049       1040/1247
(83 %)
19 diff
(98.5 %id)
BQ224205 embryonal carcinoma, cell line, testis POLE.a 2238 to 3069 1 to 842       842/862
(97 %)
15 diff
(98.3 %id)
BF760152 colon POLE.a 2253 to 2575 354 to 33     Submitted on the opposite strand 322/363
(88 %)
2 diff
(99.5 %id)
CN332487 embryonic stem cells, DMSO-treated H9 cellline POLE.a 2324 to 2669 1 to 346       346/346
(100 %)
3 diff
(99.2 %id)
CN332485 embryonic stem cells, embryoid bodiesderived from H1, H7 and H9 cells POLE.a 2569 to 3204 1 to 636       636/636
(100 %)
0 diff
(100 %id)
CX782956 human embryonic stem cells POLE.a 2587 to 3347 1 to 761       761/761
(100 %)
0 diff
(100 %id)
BE829927 lung_tumor POLE.a 2644 to 2811 167 to 1       167/170
(98 %)
1 diff
(99.5 %id)
DA756877   POLE.a 2671 to 3221 2 to 552   capped   551/551
(100 %)
1 diff
(99.9 %id)
BI013194 lung_tumor POLE.a 2725 to 3188 1 to 464       464/464
(100 %)
0 diff
(100 %id)
BQ061417 lymph, lymphoma, cell line POLE.a 2781 to 3636 1 to 861       861/1092
(78 %)
14 diff
(98.8 %id)
BQ065454 lymph, lymphoma, cell line POLE.a 2781 to 3508 1 to 732       732/964
(75 %)
10 diff
(99.0 %id)
BQ065621 lymph, lymphoma, cell line POLE.a 2781 to 3728 1 to 965       963/998
(96 %)
24 diff
(97.6 %id)
AA505176 germinal center B cell POLE.a 2907 to 3217 314 to 1     Submitted on the opposite strand 314/350
(89 %)
15 diff
(95.8 %id)
DB081234 testis POLE.a 3040 to 3548 2 to 514   capped   513/513
(100 %)
8 diff
(98.5 %id)
DA808559 brain POLE.a 3136 to 3717 2 to 583   capped   582/582
(100 %)
1 diff
(99.9 %id)
CD643292 Embryonic Stem cells POLE.a 3168 to 3899 7 to 738   tiling clone,   732/738
(99 %)
10 diff
(98.7 %id)
CX165615 human embryonic stem cells differentiated toan early endodermal cell type POLE.a 3226 to 4034 1 to 809       809/809
(100 %)
0 diff
(100 %id)
DB069974 testis POLE.a 3296 to 3818 2 to 524   capped   523/523
(100 %)
1 diff
(99.9 %id)
DA238135 brain POLE.a 3336 to 3923 2 to 589   capped   588/588
(100 %)
1 diff
(99.9 %id)
TI_2194697519   POLE.a 3432 to 4310 879 to 8       872/1146
(76 %)
6 diff
(99.5 %id)
BY996967   POLE.a 3459 to 4059 1 to 601       601/601
(100 %)
5 diff
(99.2 %id)
BF760719 colon POLE.a 3539 to 3824 17 to 300       284/312
(91 %)
9 diff
(97.2 %id)
BU521341 leiomyosarcoma, uterus POLE.a 3549 to 4394 1 to 851       851/884
(96 %)
9 diff
(99.0 %id)
DA102182 cerebellum POLE.a 3556 to 4141 2 to 586   capped   585/585
(100 %)
1 diff
(99.9 %id)
DB100196 testis POLE.a 3558 to 4137 2 to 581   capped   580/580
(100 %)
0 diff
(100 %id)
TI_2194695945   POLE.a 3600 to 4731 11 to 1130       1120/1269
(88 %)
18 diff
(98.6 %id)
CX785970 human embryonic stem cells POLE.a 3643 to 4386 1 to 744       744/744
(100 %)
1 diff
(99.9 %id)
CR988729 T-Lymphocytes POLE.a 3681 to 4307 1 to 626       626/631
(99 %)
2 diff
(99.7 %id)
CN332486 embryonic stem cells, DMSO-treated H9 cellline POLE.a 3691 to 4326 1 to 636       636/636
(100 %)
0 diff
(100 %id)
BQ441832 embryonal carcinoma, cell line, testis POLE.a 3746 to 4419 1 to 682   AAA Internal priming: the 3' end of the oligo dT primed clone lies in the CDS 680/900
(75 %)
36 diff
(96.0 %id)
TI_2194697513   POLE.a 3765 to 4772 1017 to 12       1006/1253
(80 %)
1 diff
(100.0 %id)
DB281123 uterus POLE.a 3868 to 4412 2 to 547   capped   546/546
(100 %)
1 diff
(99.9 %id)
DB218161 trachea POLE.a 3899 to 4458 2 to 561   capped   560/560
(100 %)
1 diff
(99.9 %id)
BU430019 lymph POLE.a 4047 to 4359 1 to 313       313/314
(99 %)
10 diff
(96.9 %id)
TI_2194697512   POLE.a 4104 to 5171 1057 to 11       1047/1225
(85 %)
22 diff
(98.3 %id)
BX353493 Neuroblastoma Cot 25-normalized POLE.a 4122 to 4598 1 to 480       480/812
(59 %)
13 diff
(98.4 %id)
DA114205 cerebellum POLE.a 4158 to 4719 2 to 563   capped   562/562
(100 %)
0 diff
(100 %id)
CN332483 embryonic stem cells, cell lines H1, H7, andH9 POLE.a 4159 to 4848 1 to 691       691/691
(100 %)
3 diff
(99.6 %id)
TI_2194695946   POLE.a 4176 to 5360 15 to 1181       1167/1262
(92 %)
32 diff
(97.5 %id)
DA128280 cerebellum POLE.a 4236 to 4802 2 to 568   capped   567/567
(100 %)
0 diff
(100 %id)
BI019588 marrow POLE.a 4284 to 4685 1 to 403       403/413
(97 %)
20 diff
(95.2 %id)
BI023970 marrow POLE.a 4318 to 4679 1 to 364       364/364
(100 %)
10 diff
(97.3 %id)
BM476301 duodenal adenocarcinoma, cell line, small intestine POLE.a 4330 to 5213 1 to 899       899/1072
(83 %)
36 diff
(96.7 %id)
TI_2194697528   POLE.a 4352 to 5395 1048 to 9       1040/1266
(82 %)
3 diff
(99.8 %id)
DA096033 cerebellum POLE.a 4408 to 4973 2 to 568   capped   567/567
(100 %)
2 diff
(99.7 %id)
BF899359 marrow POLE.a 4426 to 4598 1 to 172       172/179
(96 %)
1 diff
(99.5 %id)
DA448472 tongue, tumor tissue POLE.a 4432 to 4970 2 to 540   capped   539/539
(100 %)
2 diff
(99.7 %id)
BM827965 stomach POLE.a 4474 to 4956 1 to 483       483/483
(100 %)
3 diff
(99.4 %id)
DB160335 thymus POLE.a 4503 to 5074 2 to 574   capped   573/573
(100 %)
3 diff
(99.5 %id)
BC007599 Kidney, renal cell adenocarcinoma POLE.a 4510 to 7840 1 to 3331   available from MGC, AAA   3331/3331
(100 %)
3 diff
(100.0 %id)
BE274086 Kidney, renal cell adenocarcinoma POLE.a 4510 to 5227 34 to 754   available from MGC,   721/759
(94 %)
28 diff
(96.4 %id)
BC087613 Kidney, renal cell adenocarcinoma POLE.a 4510 to 7840 1 to 3331   AAA   3331/3331
(100 %)
3 diff
(100.0 %id)
DB155721 thymus POLE.a 4513 to 5037 2 to 526   capped   525/525
(100 %)
0 diff
(100 %id)
TI_2194695947   POLE.a 4517 to 5722 7 to 1198       1192/1264
(94 %)
24 diff
(98.2 %id)
TI_2194695935   POLE.a 4517 to 5584 14 to 1077       1064/1339
(79 %)
98 diff
(92.7 %id)
DB078295 testis POLE.a 4537 to 5074 2 to 539   capped   538/538
(100 %)
1 diff
(99.9 %id)
AW249200 lung, small cell carcinoma POLE.a 4596 to 5151 12 to 567       556/567
(98 %)
6 diff
(99.0 %id)
BG424864 Kidney, renal cell adenocarcinoma POLE.a 4605 to 5331 93 to 850       767/876
(87 %)
106 diff
(87.9 %id)
DA079552 cerebellum POLE.a 4622 to 5189 2 to 569   capped   568/568
(100 %)
0 diff
(100 %id)
AI902710 breast POLE.a 4628 to 5085 481 to 27       455/481
(94 %)
21 diff
(95.7 %id)
TI_2194697517   POLE.a 4628 to 5855 1229 to 21       1209/1301
(92 %)
32 diff
(97.6 %id)
BU186539 embryonal carcinoma, cell line, testis POLE.a 4751 to 5636 1 to 888       888/889
(99 %)
4 diff
(99.6 %id)
DA494013 brain POLE.a 4794 to 5355 2 to 563   capped   562/562
(100 %)
1 diff
(99.9 %id)
TI_2194695950   POLE.a 4970 to 6054 1 to 1077       1077/1251
(86 %)
17 diff
(98.7 %id)
BQ434644 eye, retinoblastoma POLE.a 5022 to 5855 12 to 854       843/942
(89 %)
18 diff
(98.1 %id)
BX482401   POLE.a 5126 to 5569 7 to 450       444/450
(98 %)
6 diff
(98.7 %id)
BU527944 epidermoid carcinoma, cell line, lung POLE.a 5182 to 6077 1 to 900       900/903
(99 %)
25 diff
(97.3 %id)
TI_2194697518   POLE.a 5212 to 6277 1066 to 8       1059/1276
(82 %)
9 diff
(99.3 %id)
CT004140 T-Lymphocytes POLE.a 5213 to 6047 1 to 836       836/837
(99 %)
6 diff
(99.3 %id)
TI_2194697536   POLE.a 5255 to 6374 1122 to 15       1108/1277
(86 %)
7 diff
(99.5 %id)
BQ049812 lymph, lymphoma, cell line POLE.a 5272 to 6250 1 to 985       985/1028
(95 %)
13 diff
(98.8 %id)
DB023380 testis POLE.a 5273 to 5821 2 to 550   capped   549/549
(100 %)
0 diff
(100 %id)
DB289665 uterus POLE.a 5341 to 5920 2 to 581   capped   580/580
(100 %)
0 diff
(100 %id)
BI023494 marrow POLE.a 5346 to 5536 192 to 3       190/192
(98 %)
1 diff
(99.5 %id)
BM477002 leiomyosarcoma, uterus POLE.a 5380 to 6185 1 to 808       808/1088
(74 %)
13 diff
(98.9 %id)
BG774035 choriocarcinoma, placenta POLE.a 5402 to 5966 1 to 565       565/572
(98 %)
9 diff
(98.5 %id)
BE281419 choriocarcinoma, placenta POLE.a 5423 to 6046 1 to 627       627/642
(97 %)
15 diff
(97.7 %id)
DA030490   POLE.a 5424 to 5998 2 to 576   capped   575/575
(100 %)
1 diff
(99.9 %id)
DA108322 cerebellum POLE.a 5425 to 5983 2 to 560   capped   559/559
(100 %)
1 diff
(99.9 %id)
DA527839 brain POLE.a 5425 to 5947 2 to 524   capped   523/523
(100 %)
0 diff
(100 %id)
AA227757 brain, neuroepithelial cells POLE.a 5466 to 5928 1 to 463       463/463
(100 %)
0 diff
(100 %id)
DA067969 cerebellum POLE.a 5508 to 6076 2 to 570   capped   569/569
(100 %)
0 diff
(100 %id)
BI115612 lung, small cell carcinoma POLE.a 5530 to 6260 1 to 738   available from MGC,   738/742
(99 %)
18 diff
(97.6 %id)
BC021559 Lung, small cell carcinoma POLE.a 5531 to 7833 1 to 2303   available from MGC, AAA   2303/2303
(100 %)
0 diff
(100 %id)
DA051566   POLE.a 5550 to 6097 2 to 549   capped   548/548
(100 %)
0 diff
(100 %id)
BQ217074 embryonal carcinoma, cell line, testis POLE.a 5582 to 6141 1 to 565       565/1004
(56 %)
8 diff
(99.3 %id)
DR763243 embryonic stem POLE.a 5584 to 6241 1 to 658       658/658
(100 %)
0 diff
(100 %id)
AL046781 testis POLE.a 5613 to 6146 1 to 534       534/534
(100 %)
0 diff
(100 %id)
TI_2194695948   POLE.a 5644 to 6855 14 to 1211       1198/1255
(95 %)
21 diff
(98.4 %id)
DA005075   POLE.a 5658 to 6219 2 to 564   capped   563/563
(100 %)
3 diff
(99.5 %id)
DA910673   POLE.a 5751 to 6254 2 to 505   capped   504/504
(100 %)
1 diff
(99.9 %id)
BP195544 brain POLE.a 5752 to 6333 1 to 582       582/582
(100 %)
2 diff
(99.7 %id)
DA077739 cerebellum POLE.a 5753 to 6327 2 to 576   capped   575/575
(100 %)
3 diff
(99.5 %id)
DA479886   POLE.a 5753 to 6247 2 to 496   capped   495/495
(100 %)
3 diff
(99.4 %id)
AU117387 whole embryo, mainly head POLE.a 5753 to 6126 2 to 375   capped   374/377
(99 %)
1 diff
(99.8 %id)
DA021156   POLE.a 5756 to 6319 2 to 565   capped   564/564
(100 %)
2 diff
(99.7 %id)
DA655756   POLE.a 5756 to 6309 2 to 555   capped   554/554
(100 %)
1 diff
(99.9 %id)
DA061294 cerebellum POLE.a 5757 to 6331 2 to 576   capped   575/575
(100 %)
0 diff
(100 %id)
AU126514   POLE.a 5758 to 6412 2 to 657   capped   656/660
(99 %)
3 diff
(99.6 %id)
DA422178 cervix POLE.a 5759 to 6342 2 to 585   capped   584/584
(100 %)
2 diff
(99.7 %id)
DA045177 bladder POLE.a 5760 to 6327 2 to 570   capped   569/569
(100 %)
2 diff
(99.7 %id)
DA053457   POLE.a 5760 to 6302 2 to 544   capped   543/543
(100 %)
0 diff
(100 %id)
DA089325 cerebellum POLE.a 5760 to 6338 2 to 580   capped   579/579
(100 %)
0 diff
(100 %id)
DA373220 thalamus POLE.a 5760 to 6330 2 to 572   capped   571/571
(100 %)
1 diff
(99.9 %id)
DA495758 brain POLE.a 5760 to 6316 2 to 558   capped   557/559
(99 %)
2 diff
(99.7 %id)
AU132356   POLE.a 5760 to 6477 2 to 719   capped   718/718
(100 %)
5 diff
(99.4 %id)
DB033376 testis POLE.a 5760 to 6308 2 to 550   capped   549/549
(100 %)
1 diff
(99.9 %id)
DA088184 cerebellum POLE.a 5761 to 6208 2 to 451   capped   450/450
(100 %)
5 diff
(98.9 %id)
DA752753   POLE.a 5761 to 6313 2 to 554   capped   553/553
(100 %)
0 diff
(100 %id)
DB121857 thymus POLE.a 5761 to 6322 2 to 563   capped   562/562
(100 %)
0 diff
(100 %id)
BP368072 thymus POLE.a 5761 to 6339 1 to 579       579/579
(100 %)
2 diff
(99.7 %id)
DA717174   POLE.a 5762 to 6294 2 to 534   capped   533/533
(100 %)
0 diff
(100 %id)
DA915172   POLE.a 5762 to 6312 2 to 552   capped   551/551
(100 %)
1 diff
(99.9 %id)
DB011034 colon, tumor tissue POLE.a 5762 to 6313 2 to 553   capped   552/552
(100 %)
2 diff
(99.7 %id)
DB033895 testis POLE.a 5762 to 6318 2 to 558   capped   557/557
(100 %)
0 diff
(100 %id)
DA006952   POLE.a 5763 to 6335 2 to 574   capped   573/573
(100 %)
1 diff
(99.9 %id)
AK025087 colon POLE.a 5763 to 7840 1 to 2078   available from FLJ, AAA   2078/2078
(100 %)
3 diff
(99.9 %id)
DA068395 cerebellum POLE.a 5763 to 6327 2 to 566   capped   565/565
(100 %)
0 diff
(100 %id)
BG259876 bladder, transitional cell papilloma, cell line POLE.a 5763 to 6456 1 to 691       691/697
(99 %)
15 diff
(97.9 %id)
DA747016   POLE.a 5763 to 6331 2 to 570   capped   569/569
(100 %)
1 diff
(99.9 %id)
DA761054 tongue POLE.a 5763 to 6298 2 to 538   capped   537/537
(100 %)
3 diff
(99.5 %id)
DA181454 amygdala POLE.a 5764 to 6336 2 to 575   capped   574/574
(100 %)
3 diff
(99.5 %id)
BM749426 stomach POLE.a 5773 to 6369 1 to 595       595/595
(100 %)
4 diff
(99.4 %id)
EL735308 mixed POLE.a 5793 to 6630 1 to 838       838/838
(100 %)
0 diff
(100 %id)
TI_1948218124   POLE.a 5793 to 6277 140 to 629   fully sequenced,   488/627
(77 %)
24 diff
(96.2 %id)
TI_1948218294   POLE.a 5793 to 6405 136 to 748   fully sequenced,   613/748
(81 %)
6 diff
(99.2 %id)
TI_1948218465   POLE.a 5793 to 6405 131 to 743   fully sequenced,   613/743
(82 %)
6 diff
(99.2 %id)
TI_1948218625   POLE.a 5793 to 6382 135 to 724       590/1365
(43 %)
12 diff
(99.2 %id)
DA612244   POLE.a 5801 to 6360 2 to 561   capped   560/560
(100 %)
1 diff
(99.9 %id)
BX480166   POLE.a 5814 to 6353 1 to 540       540/540
(100 %)
2 diff
(99.7 %id)
CN332490 embryonic stem cells, cell lines H1, H7, andH9 POLE.a 5823 to 6131 1 to 309       309/309
(100 %)
0 diff
(100 %id)
DA082478 cerebellum POLE.a 5832 to 6405 2 to 575   capped   574/574
(100 %)
0 diff
(100 %id)
DA071534 cerebellum POLE.a 5835 to 6418 2 to 586   capped   585/585
(100 %)
2 diff
(99.7 %id)
BM458272 lymph, lymphoma, cell line POLE.a 5916 to 6792 1 to 877       877/1099
(79 %)
13 diff
(98.9 %id)
BC011376 Eye, retinoblastoma POLE.a 5946 to 7840 1 to 1894   tiling clone, available from MGC, AAA   1894/1894
(100 %)
2 diff
(99.9 %id)
BG391205 embryonal carcinoma, cell line, testis POLE.a 5951 to 6576 1 to 633       633/636
(99 %)
15 diff
(97.7 %id)
AU126113   POLE.a 5956 to 6711 2 to 767   capped   766/840
(91 %)
24 diff
(97.2 %id)
TI_154163450   POLE.a 5957 to 6375 81 to 501       421/865
(48 %)
4 diff
(99.6 %id)
BX644983   POLE.a 5958 to 6226 1 to 269       269/269
(100 %)
0 diff
(100 %id)
BG479020 choriocarcinoma, placenta POLE.a 5959 to 6700 1 to 746       746/746
(100 %)
12 diff
(98.4 %id)
BE780303 eye, retinoblastoma POLE.a 5967 to 6669 1 to 700   available from MGC,   700/701
(99 %)
7 diff
(99.1 %id)
BE796142 lung, small cell carcinoma POLE.a 5977 to 6703 1 to 728       728/959
(75 %)
14 diff
(98.6 %id)
BE905991 epithelioid carcinoma, Pancreas POLE.a 5980 to 6702 1 to 727       727/810
(89 %)
15 diff
(98.2 %id)
BE895165 melanotic melanoma, skin POLE.a 5981 to 6703 1 to 727       727/859
(84 %)
17 diff
(98.1 %id)
TI_2194695965   POLE.a 5985 to 7137 1 to 1140       1140/1273
(89 %)
12 diff
(99.1 %id)
TI_2194697523   POLE.a 5991 to 6844 855 to 13       843/1094
(77 %)
10 diff
(99.1 %id)
BI022927 marrow POLE.a 6010 to 6340 333 to 2       332/333
(99 %)
0 diff
(100 %id)
BG763802 melanotic melanoma, high MDR (cell line), skin POLE.a 6043 to 6706 1 to 665       667/665
(100 %)
7 diff
(99.0 %id)
BG763920 melanotic melanoma, high MDR (cell line), skin POLE.a 6043 to 6816 1 to 779       781/780
(100 %)
13 diff
(98.4 %id)
BP268465 thyroid POLE.a 6067 to 6637 1 to 571       571/571
(100 %)
3 diff
(99.5 %id)
BG763244 melanotic melanoma, high MDR (cell line), skin POLE.a 6112 to 6896 78 to 871       792/872
(90 %)
38 diff
(95.7 %id)
BM020974 astrocytoma grade IV, cell line, brain POLE.a 6243 to 7047 1 to 806       806/806
(100 %)
5 diff
(99.4 %id)
TI_1948218125   POLE.a 6247 to 6908 784 to 121   fully sequenced,   664/784
(84 %)
5 diff
(99.4 %id)
AU133394   POLE.a 6248 to 7010 2 to 766   capped   765/765
(100 %)
11 diff
(98.6 %id)
DA968239 stomach POLE.a 6262 to 6735 2 to 477   capped   476/476
(100 %)
3 diff
(99.4 %id)
DA073997 cerebellum POLE.a 6268 to 6843 2 to 578   capped   577/577
(100 %)
1 diff
(99.9 %id)
TI_2194695080   POLE.a 6307 to 7345 1134 to 109       1026/1287
(79 %)
26 diff
(98.0 %id)
TI_2194699502   POLE.a 6310 to 7345 1133 to 105       1029/1266
(81 %)
20 diff
(98.5 %id)
TI_1948218295   POLE.a 6344 to 6908 684 to 120   fully sequenced,   565/684
(82 %)
0 diff
(100 %id)
TI_1948218466   POLE.a 6344 to 6908 686 to 121   fully sequenced,   566/686
(82 %)
0 diff
(100 %id)
BU172196 melanotic melanoma, skin POLE.a 6347 to 7095 1 to 751       751/893
(84 %)
3 diff
(99.7 %id)
W52910 parathyroid gland, parathyroid tumor POLE.a 6350 to 6793 1 to 450       450/514
(87 %)
15 diff
(97.1 %id)
DA936500 Spleen POLE.a 6366 to 6913 3 to 550   capped   548/549
(99 %)
1 diff
(99.9 %id)
TI_1948218626   POLE.a 6373 to 6908 657 to 120       538/1408
(38 %)
4 diff
(99.8 %id)
T98753 liver and spleen POLE.a 6384 to 6702 12 to 345       334/397
(84 %)
23 diff
(94.3 %id)
BE714559 head_neck POLE.a 6407 to 6723 1 to 317       317/317
(100 %)
10 diff
(96.9 %id)
BE714575 head_neck POLE.a 6408 to 6723 5 to 319       315/319
(98 %)
6 diff
(98.2 %id)
BE714540 head_neck POLE.a 6409 to 6723 20 to 333       314/333
(94 %)
6 diff
(98.2 %id)
BF921926 nervous_tumor POLE.a 6494 to 6882 5 to 391       387/391
(98 %)
8 diff
(98.0 %id)
BI116527 lung, small cell carcinoma POLE.a 6508 to 7374 1 to 868       868/888
(97 %)
45 diff
(95.0 %id)
AL044579 testis POLE.a 6519 to 7073 1 to 556       556/556
(100 %)
3 diff
(99.5 %id)
BG744086 blood, natural killer cells, cell line POLE.a 6529 to 7147 1 to 615   fully sequenced,   615/615
(100 %)
4 diff
(99.4 %id)
TI_2194697511   POLE.a 6559 to 7345 957 to 173       785/1236
(63 %)
15 diff
(98.8 %id)
BQ222760 epithelioid carcinoma, Pancreas POLE.a 6573 to 7476 1 to 916       916/918
(99 %)
31 diff
(96.7 %id)
AL045426 testis POLE.a 6582 to 7048 1 to 467       467/472
(98 %)
1 diff
(99.8 %id)
TI_2194695951   POLE.a 6595 to 7345 19 to 769       751/1256
(59 %)
12 diff
(99.1 %id)
BU181616 eye, retinoblastoma POLE.a 6698 to 7428 1 to 747       747/906
(82 %)
32 diff
(96.5 %id)
DA094376 cerebellum POLE.a 6705 to 7233 2 to 530   capped   529/529
(100 %)
0 diff
(100 %id)
BM849703 stomach POLE.a 6746 to 7122 1 to 377       377/377
(100 %)
0 diff
(100 %id)
BM478237 lymph, lymphoma, cell line POLE.a 6770 to 7798 1 to 1034       1034/1034
(100 %)
27 diff
(97.4 %id)
BG820879 anaplastic oligodendroglioma with 1p/19qloss, brain POLE.a 6797 to 7431 11 to 644       634/644
(98 %)
6 diff
(99.1 %id)
BQ361109 ovary POLE.a 6818 to 7144 329 to 4       326/331
(98 %)
0 diff
(100 %id)
EC513094 Prostate POLE.a 6854 to 6948 1 to 95       95/95
(100 %)
0 diff
(100 %id)
CN415292 embryonic stem cell, retinoic acid andmitogen-treated hES cell line H7 POLE.a 6880 to 7534 1 to 655       655/655
(100 %)
1 diff
(99.9 %id)
BF973687 leiomyosarcoma cell line, uterus POLE.a 6891 to 7625 22 to 748       727/957
(75 %)
22 diff
(97.8 %id)
BE546036 cervical carcinoma cell line, cervix POLE.a 6961 to 7560 1 to 604       604/614
(98 %)
13 diff
(97.9 %id)
AW836320 leiomios POLE.a 7060 to 7459 16 to 415       400/423
(94 %)
7 diff
(98.4 %id)
CB409321 maxilla, pooled POLE.a 7090 to 7560 1 to 471       471/475
(99 %)
4 diff
(99.2 %id)
BF753070 breast_normal POLE.a 7101 to 7289 11 to 190       180/190
(94 %)
6 diff
(96.9 %id)
BG744753 blood, natural killer cells, cell line POLE.a 7117 to 7791 673 to 1   fully sequenced,   673/673
(100 %)
6 diff
(99.2 %id)
BF727316 eye, lens POLE.a 7133 to 7592 1 to 460       460/460
(100 %)
1 diff
(99.8 %id)
BX093066 multiple sclerosis lesions POLE.a 7181 to 7366 1 to 185       185/185
(100 %)
1 diff
(99.5 %id)
AA970895 2 pooled tumors (clear cell type), Kidney POLE.a 7186 to 7560 383 to 7       377/383
(98 %)
0 diff
(100 %id)
BE004501 breast_normal POLE.a 7232 to 7462 428 to 198     Submitted on the opposite strand 231/428
(53 %)
0 diff
(100 %id)
DW465033 Liver POLE.a 7250 to 7593 17 to 360       344/360
(95 %)
6 diff
(98.4 %id)
DB369356   POLE.a 7311 to 7840 547 to 1       547/547
(100 %)
29 diff
(94.7 %id)
DB355173 whole embryo, mainly head POLE.a 7340 to 7843 513 to 1   tiling clone,   513/570
(90 %)
17 diff
(97.1 %id)
CX782878 human embryonic stem cells POLE.a 7375 to 7847 498 to 26   AAA   473/473
(100 %)
6 diff
(98.8 %id)
AA455188 ovarian tumor, ovary POLE.a 7418 to 7555 1 to 136       136/136
(100 %)
7 diff
(94.9 %id)
AL044580 testis POLE.a 7441 to 7841 414 to 12   AAA   403/411
(98 %)
2 diff
(99.6 %id)
AA227758 brain, neuroepithelial cells POLE.a 7450 to 7840 392 to 2       391/392
(99 %)
0 diff
(100 %id)
EC521353 Prostate POLE.a 7467 to 7572 1 to 106       106/106
(100 %)
6 diff
(94.4 %id)
AA037353 parathyroid gland, parathyroid tumor POLE.a 7582 to 7840 260 to 1       260/260
(100 %)
1 diff
(99.7 %id)
AA768922 germinal center B cell POLE.a 7613 to 7840 250 to 23   AAA   228/228
(100 %)
0 diff
(100 %id)
AL046185 testis POLE.a 7618 to 7840 1 to 223       223/245
(91 %)
3 diff
(98.8 %id)
AI624906 pooled germ cell tumors POLE.a 7620 to 7840 221 to 1       221/221
(100 %)
0 diff
(100 %id)
BF223018 pooled germ cell tumors POLE.a 7620 to 7840 222 to 1       222/222
(100 %)
1 diff
(99.6 %id)
AA470641 colon POLE.a 7667 to 7840 190 to 17   AAA   174/174
(100 %)
0 diff
(100 %id)
AA935144 pooled POLE.a 7678 to 7835 160 to 3       158/160
(98 %)
0 diff
(100 %id)
CA337078 posterior rhombomeres 5-8 (4 pooled) POLE.a 7710 to 7840 1 to 131       131/200
(65 %)
2 diff
(99.0 %id)
AW769584 2 pooled Wilms' tumors, one primary and onemetastatic to brain, Kidney POLE.a 7723 to 7840 117 to 1       117/117
(100 %)
1 diff
(99.2 %id)
S60080   POLE.b 1 to 6800 1 to 6794 K406S A407K K408L L409G G410Y ... tiling clone,   6794/6794
(100 %)
14 diff
(99.8 %id)
AL043786 testis POLE.b 2884 to 3554 1 to 671   tiling clone,   671/671
(100 %)
0 diff
(100 %id)
AL043787 testis POLE.b 6683 to 7252 575 to 8   tiling clone,   568/575
(98 %)
1 diff
(99.9 %id)
BX647647 human skeletal muscle POLE.c 1 to 5417 34 to 5450 I383T L518P K593E L872Q tiling clone, available from DKFZ, AAA   5417/5417
(100 %)
5 diff
(100.0 %id)
TI_2194695072   POLE.d 1 to 1018 88 to 1101       1014/1267
(80 %)
17 diff
(98.7 %id)
TI_2194699125   POLE.d 1 to 1033 82 to 1098   tiling clone,   1020/1244
(81 %)
27 diff
(97.9 %id)
BC144561 Brain, cerebellum, PCR rescued clones POLE.d 2 to 8012 1 to 8011 exact tiling clone,   8011/8011
(100 %)
1 diff
(100.0 %id)
TI_2194697532   POLE.d 279 to 1452 11 to 1168       1158/1263
(91 %)
22 diff
(98.3 %id)
TI_2194697534   POLE.d 746 to 1936 17 to 1186       1174/1259
(93 %)
16 diff
(98.8 %id)
TI_2194695969   POLE.d 2636 to 3867 10 to 1231       1222/1277
(95 %)
22 diff
(98.3 %id)
TI_2194697530   POLE.d 2782 to 3946 13 to 1170       1158/1265
(91 %)
16 diff
(98.8 %id)
TI_2194695968   POLE.d 3123 to 4181 1 to 1051       1051/1250
(84 %)
16 diff
(98.8 %id)
TI_2194697524   POLE.d 3237 to 4316 6 to 1075       1070/1233
(86 %)
24 diff
(98.1 %id)
DA101158 cerebellum POLE.d 3752 to 4345 2 to 595   capped   594/594
(100 %)
2 diff
(99.7 %id)
BM467737 leiomyosarcoma, uterus POLE.e 1 to 1055 6 to 1062   tiling clone,   1060/1081
(98 %)
32 diff
(97.1 %id)
DB136136 thymus POLE.e 939 to 1445 2 to 508   tiling clone, capped   507/507
(100 %)
0 diff
(100 %id)
DB161333 thymus POLE.e 1099 to 1684 2 to 587   tiling clone, capped   586/586
(100 %)
0 diff
(100 %id)
DA944094 Spleen POLE.e 1195 to 1761 2 to 568   tiling clone, capped   567/567
(100 %)
3 diff
(99.5 %id)
BG955396 colon POLE.e 1197 to 1763 603 to 38       566/603
(93 %)
0 diff
(100 %id)
BG956346 colon POLE.e 1197 to 1763 603 to 38       566/603
(93 %)
0 diff
(100 %id)
BI023513 marrow POLE.e 1441 to 1808 381 to 14       368/381
(96 %)
0 diff
(100 %id)
BG396757 eye, retinoblastoma POLE.e 1537 to 2248 1 to 711   tiling clone,   711/711
(100 %)
3 diff
(99.6 %id)
BF802971 colon_ins POLE.e 1712 to 2090 405 to 14     Submitted on the opposite strand 392/405
(96 %)
11 diff
(97.3 %id)
BF808966 colon_ins POLE.e 1712 to 2076 1 to 365   tiling clone,   365/365
(100 %)
4 diff
(99.0 %id)
DB242336 stomach, tumor tissue POLE.e 1736 to 2227 2 to 494   capped   493/493
(100 %)
1 diff
(99.8 %id)
CN332484 embryonic stem cells, cell lines H1, H7, andH9 POLE.e 1764 to 2227 1 to 464       464/464
(100 %)
0 diff
(100 %id)
DA808790 brain POLE.e 2102 to 2642 2 to 542   tiling clone, capped   541/541
(100 %)
0 diff
(100 %id)
BY797372 eye POLE.e 2445 to 3034 1 to 590   tiling clone,   590/590
(100 %)
1 diff
(99.9 %id)
BF435001 fibrotheoma, ovary POLE.e 2855 to 3192 1 to 338   tiling clone, Submitted on the opposite strand 338/338
(100 %)
0 diff
(100 %id)
TI_2016725231   POLE.f 1 to 966 1 to 966   tiling clone,   966/969
(99 %)
24 diff
(97.6 %id)
DA070846 cerebellum POLE.f 790 to 1344 2 to 556   tiling clone, capped   555/555
(100 %)
0 diff
(100 %id)
DB041450 testis POLE.f 1237 to 1786 2 to 551   tiling clone, capped   550/550
(100 %)
5 diff
(99.1 %id)
T98586 liver and spleen POLE.f 1349 to 1509 1 to 161       161/161
(100 %)
0 diff
(100 %id)
AL080203 testis POLE.f 1370 to 2971 1 to 1599   tiling clone, available from DKFZ,   1602/1604
(99 %)
4 diff
(99.8 %id)
BQ896014 eye, retinoblastoma POLE.f 1596 to 2160 1 to 582       585/1027
(56 %)
26 diff
(97.5 %id)
T98396 liver and spleen POLE.f 1597 to 1666 1 to 70       70/70
(100 %)
4 diff
(94.3 %id)
BM692718 eye, Retina Foveal and Macular POLE.f 1931 to 2072 1 to 142       142/142
(100 %)
0 diff
(100 %id)
R67657 breast POLE.f 1942 to 2043 1 to 102       102/102
(100 %)
0 diff
(100 %id)
AF128544   POLE.f 2034 to 2971 1 to 938   AAA   938/938
(100 %)
5 diff
(99.5 %id)
AL580853 T cells from T cell leukemia POLE.f 2100 to 2915 816 to 1       816/816
(100 %)
7 diff
(99.2 %id)
CN415293 embryonic stem cells, cell lines H1, H7, andH9 POLE.f 2131 to 2751 1 to 620       620/620
(100 %)
1 diff
(99.9 %id)
CV807726 Blastocyst, pluripotent cell line derived fromblastocyst inner cell mass POLE.f 2192 to 2972 1 to 780   AAA   780/780
(100 %)
27 diff
(96.6 %id)
CA307250 Alveolar Macrophage, lung POLE.f 2245 to 2971 743 to 17   AAA   727/727
(100 %)
3 diff
(99.6 %id)
AA284707 ovarian tumor, ovary POLE.f 2265 to 2661 1 to 393   fully sequenced,   393/393
(100 %)
17 diff
(95.7 %id)
BU734019 eye, Retina Foveal and Macular POLE.f 2301 to 2980 687 to 19   tiling clone, AAA   669/699
(95 %)
14 diff
(98.0 %id)
BP420994 small intestine POLE.f 2308 to 2817 1 to 510     Submitted on the opposite strand 510/510
(100 %)
0 diff
(100 %id)
N53193 multiple sclerosis lesions POLE.f 2383 to 2543 1 to 163   fully sequenced,   163/163
(100 %)
6 diff
(96.4 %id)
BE783124 eye, retinoblastoma POLE.f 2428 to 2965 1 to 538       538/538
(100 %)
1 diff
(99.9 %id)
DB333396 Spleen POLE.f 2443 to 2974 532 to 1       532/532
(100 %)
1 diff
(99.9 %id)
AW043685 pooled POLE.f 2445 to 2964 520 to 1       520/520
(100 %)
3 diff
(99.5 %id)
AW044660 pooled POLE.f 2459 to 2964 506 to 1       506/506
(100 %)
3 diff
(99.5 %id)
DB341805 testis POLE.f 2464 to 2971 508 to 1       508/508
(100 %)
2 diff
(99.7 %id)
BF109401 pooled POLE.f 2468 to 2966 501 to 3       499/501
(99 %)
0 diff
(100 %id)
AI672781 colon, colonic mucosa from 3 patients with Crohn'sdisease POLE.f 2479 to 2966 492 to 5       488/492
(99 %)
0 diff
(100 %id)
AI916186 colon, colon tumor, RER+ POLE.f 2484 to 2974 491 to 1       491/491
(100 %)
2 diff
(99.6 %id)
AA974562 pooled POLE.f 2487 to 2971 488 to 7       482/490
(98 %)
0 diff
(100 %id)
AI094398 brain, glioblastoma (pooled) POLE.f 2510 to 2971 460 to 2       459/460
(99 %)
0 diff
(100 %id)
R85494 brain POLE.f 2519 to 2967 457 to 4       454/462
(98 %)
0 diff
(100 %id)
N51530 multiple sclerosis lesions POLE.f 2519 to 2971 463 to 1   fully sequenced,   463/463
(100 %)
14 diff
(97.0 %id)
AI970385 pooled germ cell tumors POLE.f 2522 to 2971 450 to 1       450/450
(100 %)
4 diff
(99.2 %id)
T65516 whole brain POLE.f 2532 to 2941 1 to 416       416/420
(99 %)
21 diff
(95.0 %id)
R67658 breast POLE.f 2549 to 2971 427 to 1       427/427
(100 %)
6 diff
(98.6 %id)
AI277712 mixed (see below), Pooled human melanocyte, fetal heart, andpregnant uterus POLE.f 2549 to 2971 425 to 3       423/425
(99 %)
0 diff
(100 %id)
TI_157602955   POLE.f 2557 to 2971 509 to 95   tiling clone, AAA   415/536
(77 %)
0 diff
(100 %id)
AA578667 colon, tumor POLE.f 2559 to 2974 416 to 1       416/416
(100 %)
1 diff
(99.8 %id)
BE049347 adenocarcinoma, Pancreas POLE.f 2561 to 2966 411 to 6       406/412
(98 %)
0 diff
(100 %id)
AI911787 pooled POLE.f 2562 to 2971 441 to 32   AAA   410/410
(100 %)
20 diff
(95.2 %id)
AA456280 mixed (see below), Pooled human melanocyte, fetal heart, andpregnant uterus POLE.f 2568 to 2955 1 to 387       387/387
(100 %)
1 diff
(99.8 %id)
AI690955 poorly-differentiated endometrialadenocarcinoma, 2 pooled tumors, uterus POLE.f 2572 to 2964 407 to 15   AAA   393/394
(99 %)
2 diff
(99.5 %id)
AI564263 uterus, well-differentiated endometrialadenocarcinoma, 7 pooled tumors POLE.f 2572 to 2970 399 to 1       399/399
(100 %)
0 diff
(100 %id)
AW302483 brain, three pooled meningiomas POLE.f 2572 to 2971 400 to 1       400/409
(97 %)
0 diff
(100 %id)
AW594546 pooled germ cell tumors POLE.f 2572 to 2970 412 to 14   AAA   399/408
(97 %)
6 diff
(98.6 %id)
AI682145 serous papillary carcinoma, high grade, 2pooled tumors, uterus POLE.f 2573 to 2971 390 to 1       390/390
(100 %)
17 diff
(95.7 %id)
AI023678 liver and spleen POLE.f 2590 to 2971 382 to 1       382/382
(100 %)
1 diff
(99.8 %id)
BF000804 malignant melanoma, metastatic to lymphnode, skin POLE.f 2591 to 2979 387 to 1       387/387
(100 %)
2 diff
(99.5 %id)
BM929688 eye, fetal eyes, lens, eye anterior segment,optic nerve, retina, Retina Foveal and Macular, RPE andChoroid POLE.f 2594 to 2971 28 to 405   fully sequenced, AAA   378/405
(93 %)
6 diff
(98.6 %id)
AA680129 liver and spleen POLE.f 2596 to 2892 298 to 1       298/298
(100 %)
1 diff
(99.7 %id)
AI538620 poorly-differentiated endometrialadenocarcinoma, 2 pooled tumors, uterus POLE.f 2596 to 2971 379 to 4       376/379
(99 %)
0 diff
(100 %id)
AI695123 colon POLE.f 2596 to 2974 405 to 27   AAA   379/379
(100 %)
5 diff
(98.7 %id)
BP388229 pancreatic islet POLE.f 2600 to 2910 1 to 311     Submitted on the opposite strand 311/311
(100 %)
2 diff
(99.4 %id)
AW235194 pooled germ cell tumors POLE.f 2600 to 2971 399 to 20   AAA   380/380
(100 %)
13 diff
(96.6 %id)
T98587 liver and spleen POLE.f 2601 to 2970 379 to 2       378/381
(99 %)
0 diff
(100 %id)
AI378414 mixed (see below), Pooled human melanocyte, fetal heart, andpregnant uterus POLE.f 2601 to 2971 374 to 4       371/374
(99 %)
0 diff
(100 %id)
AI439366 lymph node, lymphoma, follicular mixed small and largecell POLE.f 2601 to 2971 407 to 38   AAA   370/370
(100 %)
16 diff
(95.7 %id)
AI243291 pooled POLE.f 2602 to 2971 401 to 32   AAA   370/370
(100 %)
11 diff
(97.1 %id)
BE645649 Prostate POLE.f 2605 to 2971 367 to 1       367/367
(100 %)
5 diff
(98.7 %id)
AA287136 ovarian tumor, ovary POLE.f 2631 to 2964 334 to 1   fully sequenced,   334/334
(100 %)
1 diff
(99.8 %id)
BM683632 eye, fetal eyes, lens, eye anterior segment,optic nerve, retina, Retina Foveal and Macular, RPE andChoroid POLE.f 2633 to 2971 357 to 19   fully sequenced, AAA   339/339
(100 %)
0 diff
(100 %id)
AI274732 uterus, well-differentiated endometrialadenocarcinoma, 7 pooled tumors POLE.f 2634 to 2975 342 to 1       342/342
(100 %)
0 diff
(100 %id)
BF439715 brain, glioblastoma (pooled) POLE.f 2643 to 2971 329 to 1       329/329
(100 %)
1 diff
(99.7 %id)
BE049361 adenocarcinoma, Pancreas POLE.f 2644 to 2966 327 to 6       322/329
(97 %)
0 diff
(100 %id)
AA968588 pooled POLE.f 2648 to 2966 320 to 3       318/320
(99 %)
0 diff
(100 %id)
AA766350 germinal center B cell POLE.f 2649 to 2971 331 to 10       322/331
(97 %)
0 diff
(100 %id)
AA714569 germinal center B cell POLE.f 2650 to 2971 331 to 10       322/331
(97 %)
0 diff
(100 %id)
AA233317.
matches multiple genes
mixed (see below), Pooled human melanocyte, fetal heart, andpregnant uterus POLE.f 2652 to 2971 319 to 2     also hits gene deesee 318/319
(99 %)
0 diff
(100 %id)
AW196559 pooled germ cell tumors POLE.f 2654 to 2971 326 to 1       326/350
(93 %)
6 diff
(98.3 %id)
AA506328 Prostate POLE.f 2657 to 2971 357 to 43   AAA   315/315
(100 %)
0 diff
(100 %id)
AA783009   POLE.f 2676 to 2968 296 to 6       291/296
(98 %)
0 diff
(100 %id)
AI365197 pooled germ cell tumors POLE.f 2701 to 2969 268 to 2       267/268
(99 %)
0 diff
(100 %id)
AI203179 pooled germ cell tumors POLE.f 2705 to 2970 270 to 5       266/270
(98 %)
0 diff
(100 %id)
AW024063 pooled germ cell tumors POLE.f 2706 to 2970 269 to 5       265/269
(98 %)
0 diff
(100 %id)
T98397 liver and spleen POLE.f 2817 to 2970 155 to 3       153/155
(98 %)
0 diff
(100 %id)
DA041693 bladder POLE.g 1 to 555 2 to 557   tiling clone, capped   556/556
(100 %)
5 diff
(99.2 %id)
DA867136 Prostate POLE.g 6 to 516 2 to 512   tiling clone, capped   511/511
(100 %)
1 diff
(99.9 %id)
BP366473 thymus POLE.g 6 to 580 1 to 575       575/580
(99 %)
14 diff
(97.6 %id)
AL559184 T cells from T cell leukemia POLE.g 500 to 1291 1 to 791       791/791
(100 %)
47 diff
(94.1 %id)
DA872638 Prostate POLE.g 532 to 1097 2 to 567   tiling clone, capped   566/566
(100 %)
1 diff
(99.9 %id)
TI_57234827   POLE.g 604 to 1429 25 to 854       830/854
(97 %)
11 diff
(98.8 %id)
BI909593 leukocyte POLE.g 615 to 1429 1 to 819   tiling clone,   819/819
(100 %)
6 diff
(99.3 %id)
TI_59389090   POLE.g 643 to 1446 104 to 908   tiling clone,   805/805
(100 %)
4 diff
(99.6 %id)
DB091771 testis POLE.h 1 to 555 2 to 556   tiling clone, capped   555/555
(100 %)
1 diff
(99.9 %id)
BX493014   POLE.h 543 to 1129 1 to 587   tiling clone,   587/587
(100 %)
0 diff
(100 %id)
BF900513 marrow POLE.h 631 to 890 1 to 256       256/299
(85 %)
6 diff
(98.0 %id)
AL703760 human skeletal muscle POLE.i 1 to 531 1 to 532 A173T K174Q V175G tiling clone,   532/532
(100 %)
7 diff
(98.7 %id)
DA520921 brain POLE.j 1 to 565 2 to 566 G109R S133C tiling clone, capped   565/565
(100 %)
2 diff
(99.7 %id)
AA504850 germinal center B cell POLE.k 1 to 376 1 to 376   tiling clone, Submitted on the opposite strand 376/376
(100 %)
0 diff
(100 %id)
AA766186 germinal center B cell POLE.k 1 to 481 1 to 479   tiling clone, Submitted on the opposite strand 479/479
(100 %)
23 diff
(95.2 %id)
AI025640 parathyroid gland, parathyroid tumor POLE.l 1 to 483 1 to 479 D12T M13C C14A R15G M16C ... tiling clone, Submitted on the opposite strand 479/479
(100 %)
5 diff
(99.0 %id)
AI028437 parathyroid gland, parathyroid tumor POLE.l 87 to 503 1 to 417   tiling clone, Submitted on the opposite strand 417/417
(100 %)
0 diff
(100 %id)
BF946875 nervous_normal POLE.m-u 1 to 390 18 to 406   tiling clone,   389/406
(95 %)
6 diff
(98.6 %id)
CV319237 nervous_normal POLE.m-u 12 to 390 1 to 386       386/386
(100 %)
27 diff
(93.1 %id)
BF946868 nervous_normal POLE.m-u 13 to 384 1 to 372   tiling clone,   372/372
(100 %)
2 diff
(99.5 %id)
BF946712 nervous_normal POLE.m-u 14 to 334 1 to 325       325/325
(100 %)
19 diff
(94.2 %id)
BF946713 nervous_normal POLE.m-u 15 to 373 1 to 358       358/358
(100 %)
9 diff
(97.5 %id)
BF946772 nervous_normal POLE.m-u 15 to 467 1 to 453       453/453
(100 %)
5 diff
(98.9 %id)
BF946865 nervous_normal POLE.m-u 15 to 362 1 to 348       348/348
(100 %)
0 diff
(100 %id)
BF946881 nervous_normal POLE.m-u 15 to 445 1 to 431       431/431
(100 %)
1 diff
(99.8 %id)
BF946768 nervous_normal POLE.m-u 29 to 452 1 to 425       425/425
(100 %)
10 diff
(97.7 %id)
BF946882 nervous_normal POLE.m-u 31 to 401 1 to 369       369/369
(100 %)
9 diff
(97.6 %id)
BF946769 nervous_normal POLE.m-u 37 to 451 1 to 414       414/414
(100 %)
9 diff
(97.9 %id)
BF946760 nervous_normal POLE.m-u 121 to 554 437 to 2       436/437
(99 %)
0 diff
(100 %id)
CV319243 nervous_normal POLE.m-u 125 to 468 346 to 3     Submitted on the opposite strand 344/346
(99 %)
0 diff
(100 %id)
CV319241 nervous_normal POLE.m-u 141 to 544 407 to 1     Submitted on the opposite strand 407/407
(100 %)
14 diff
(96.6 %id)
BF946770 nervous_normal POLE.m-u 149 to 558 433 to 9       425/433
(98 %)
0 diff
(100 %id)
BF946871 nervous_normal POLE.m-u 151 to 574 426 to 4   tiling clone,   423/426
(99 %)
0 diff
(100 %id)
BF946880 nervous_normal POLE.m-u 189 to 566 401 to 26       376/401
(93 %)
0 diff
(100 %id)
BF946706 nervous_normal POLE.m-u 192 to 570 393 to 14   tiling clone,   380/393
(96 %)
0 diff
(100 %id)
BF946716 nervous_normal POLE.m-u 212 to 546 336 to 2       335/336
(99 %)
0 diff
(100 %id)
BF946711 nervous_normal POLE.m-u 213 to 539 328 to 2       327/328
(99 %)
0 diff
(100 %id)
BF946707 nervous_normal POLE.m-u 214 to 557 343 to 2       342/343
(99 %)
0 diff
(100 %id)
CV319234 nervous_normal POLE.m-u 223 to 529 310 to 2     Submitted on the opposite strand 309/310
(99 %)
0 diff
(100 %id)
BF946763 nervous_normal POLE.m-u 245 to 552 307 to 1       307/307
(100 %)
6 diff
(98.1 %id)
CV319235 nervous_normal POLE.m-u 261 to 553 297 to 1     Submitted on the opposite strand 297/297
(100 %)
0 diff
(100 %id)
BF946630 nervous_normal POLE.m-u 270 to 565 300 to 4       297/300
(99 %)
0 diff
(100 %id)
BF946632 nervous_normal POLE.m-u 284 to 556 278 to 1       278/278
(100 %)
22 diff
(92.1 %id)
CN332489 embryonic stem cells, embryoid bodiesderived from H1, H7 and H9 cells POLE.n 1 to 660 1 to 660 exact tiling clone,   660/660
(100 %)
2 diff
(99.7 %id)
BP311043 brain POLE.n 11 to 592 1 to 582 D38G S118P tiling clone,   582/582
(100 %)
11 diff
(98.2 %id)
DA155609 amygdala POLE.n 17 to 593 2 to 578 exact capped   577/577
(100 %)
1 diff
(99.9 %id)
DA070651 cerebellum POLE.n 18 to 561 2 to 545 exact capped   544/544
(100 %)
0 diff
(100 %id)
DB000911 breast, tumor tissue POLE.n 653 to 1187 2 to 536   tiling clone, capped   535/535
(100 %)
2 diff
(99.7 %id)
BF868749 lung_tumor POLE.o 1 to 366 1 to 366 exact tiling clone,   366/366
(100 %)
3 diff
(99.2 %id)
BI008451 kidney_tumor POLE.o 195 to 566 6 to 376   tiling clone,   371/390
(95 %)
10 diff
(97.5 %id)
BF810310 colon_ins POLE.o 545 to 860 1 to 316   tiling clone,   316/316
(100 %)
5 diff
(98.5 %id)
BF765221 colon_est POLE.o 800 to 1000 210 to 10   tiling clone, Submitted on the opposite strand 201/210
(95 %)
0 diff
(100 %id)
AI631774 Kidney POLE.p 1 to 330 330 to 1 exact tiling clone,   330/330
(100 %)
0 diff
(100 %id)
AF128542   POLE.q 1 to 217 1 to 217   tiling clone,   217/217
(100 %)
0 diff
(100 %id)
BF883728 lung_tumor POLE.q 106 to 469 1 to 364 exact tiling clone,   364/364
(100 %)
0 diff
(100 %id)
BX489767   POLE.r 1 to 244 1 to 243 F18L N19I K20S P21L G22E ... tiling clone,   243/243
(100 %)
1 diff
(99.6 %id)
BF833000 head_neck POLE.s 1 to 299 19 to 317 exact tiling clone,   304/317
(95 %)
6 diff
(98.2 %id)
CV801153 Blastocyst, pluripotent cell line derived fromblastocyst inner cell mass POLE.t 1 to 747 1 to 736 N36T R37V I38F S39L T40H ... tiling clone,   736/804
(91 %)
12 diff
(98.6 %id)
AK128248 thymus POLE.u 1 to 2095 2 to 2096   tiling clone, available from FLJ,   2096/2096
(100 %)
3 diff
(99.9 %id)
DB115038 thymus POLE.u 1 to 439 2 to 440   capped   439/439
(100 %)
0 diff
(100 %id)
DB343595 thymus POLE.u 1548 to 2095 548 to 1       548/548
(100 %)
2 diff
(99.7 %id)
DB370359   POLE.va-u 1 to 294 294 to 1 S7X E9X R15X S20X T22X ... tiling clone,   294/299
(98 %)
5 diff
(98.4 %id)
BC152398 PCR rescued clones POLE.va-u 101 to 785 15 to 700   tiling clone,   686/707
(97 %)
4 diff
(99.5 %id)
AL704629 human skeletal muscle POLE.vb-u 1 to 567 1 to 567   tiling clone,   567/567
(100 %)
0 diff
(100 %id)
DA116719 cerebellum POLE.vb-u 139 to 728 2 to 591 exact tiling clone, capped   590/590
(100 %)
0 diff
(100 %id)
DB153940 thymus POLE.vc-u 1 to 574 2 to 575 exact tiling clone, capped   574/574
(100 %)
0 diff
(100 %id)
BF882200 lung_tumor POLE.vd-u 1 to 237 1 to 237 P10S S14F S20F H22R R28K ... tiling clone,   237/237
(100 %)
15 diff
(93.7 %id)
CV375735 nervous_tumor POLE.vd-u 89 to 368 1 to 283   tiling clone,   283/287
(98 %)
18 diff
(93.8 %id)
DB096944 testis POLE.ve-u 1 to 276 2 to 278 W16M W17V R18A M19H P20A ... tiling clone, capped   277/277
(100 %)
1 diff
(99.7 %id)
AW805787 uterus POLE.vf 1 to 227 1 to 226 P3L D4I C5A S6P T7L ... tiling clone,   226/227
(99 %)
5 diff
(97.8 %id)
AK093003 Spleen Gene POLE, variant not shown       available from FLJ, Suspected internal deletion, this clone was ignored    
TI_2194695949   Gene POLE, variant not shown         This clone was ignored    
BF946633 nervous_normal Gene POLE, variant not shown         This clone was ignored    
BF946635 nervous_normal Gene POLE, variant not shown         This clone was ignored    
BG986386 head_neck Gene POLE, variant not shown         Suspected internal deletion, this clone was ignored    
BX100363 pooled germ cell tumors Gene POLE, variant not shown         This clone was ignored    
F09552 brain, total brain Gene POLE, variant not shown         This clone was ignored    
F11905 brain, total brain Gene POLE, variant not shown         This clone was ignored    
CF135222 CNCAP(3)T-225 cell line, Prostate Gene POLE, variant not shown         This clone was ignored    
CD300423 testis Gene POLE, variant not shown         This clone was ignored    
? Gene Summary Gene on genome mRNA:.a, .b, .c, .d, .e, .f, .g, .h, .i, .j, .k, .l, .m-u, .n, .o, .p, .q, .r, .s, .t, .u, .va-u, .vb-u, .vc-u, .vd-u, .ve-u, .vf Alternative mRNAs features, proteins, introns, exons, sequences Expression Tissue Function, regulation, related genes CI