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Gene ADAM17TABLE OF CONTENTS / OPEN CLOSE ALL PARAGRAPHS
Summary back to top
Compact gene diagram back to top
136 supporting clones for gene ADAM17 back to top
cDNA accession
Links to the sequence
Tissue

most 5' clones
in red
Match
mRNA
From bp
to bp
in mRNA
From bp
to bp
in accs.
Clone encodes
complete protein
(with AA variation)
Features Anomalies
detected by
AceView
Accession
match over
(% length)
Base differences
relative to genome
(% identity)
GQ402545   .a 1 to 3544 8 to 3551 exact tiling clone, AAA Possibly primed on the genome, locally A rich (24/24 A in genome downstream of last aligned base) 3551/3551
(100 %)
0 diff
(100 %id)
NM_003183.4   .a 1 to 3544 8 to 3551 exact RefSeq, AAA Possibly primed on the genome, locally A rich (24/24 A in genome downstream of last aligned base) 3551/3551
(100 %)
0 diff
(100 %id)
DB151067 thymus .a 1 to 145 8 to 152   capped   151/151
(100 %)
1 diff
(99.4 %id)
DB282453 uterus .a 1 to 538 8 to 545   capped   544/544
(100 %)
1 diff
(99.9 %id)
DA553486   .a 1 to 254 2 to 255   capped   254/254
(100 %)
2 diff
(99.3 %id)
CR735526 testis .a 11 to 398 1 to 388       388/388
(100 %)
1 diff
(99.8 %id)
U92649 arthritis-affected cartilage .a 13 to 3544 1 to 3523 V109A D563N T801A D818N     3523/3523
(100 %)
20 diff
(99.5 %id)
U86755   .a 14 to 2950 1 to 2942 exact     2942/2942
(100 %)
14 diff
(99.6 %id)
AU098443   .a 20 to 270 1 to 251       251/300
(83 %)
6 diff
(98.0 %id)
DA230021 brain .a 25 to 552 2 to 529   capped   528/528
(100 %)
0 diff
(100 %id)
BX642552   .a 26 to 625 1 to 601       601/601
(100 %)
3 diff
(99.6 %id)
BP872759 embryonal kidney .a 27 to 610 1 to 582       582/582
(100 %)
13 diff
(97.8 %id)
DA240643 brain .a 28 to 617 2 to 591   capped   590/590
(100 %)
0 diff
(100 %id)
DB276653 uterus .a 29 to 552 2 to 525   capped   524/524
(100 %)
0 diff
(100 %id)
AI910050 breast .a 49 to 463 1 to 415       415/415
(100 %)
1 diff
(99.8 %id)
U69611   .a 63 to 3076 1 to 3014 exact     3014/3014
(100 %)
5 diff
(99.9 %id)
DA173101 amygdala .a 66 to 602 2 to 539   capped   538/538
(100 %)
2 diff
(99.7 %id)
DB152753 thymus .a 66 to 642 2 to 578   capped   577/577
(100 %)
0 diff
(100 %id)
BC136783 Brain, cerebellum, PCR rescued clones .a 100 to 3495 1 to 3389 exact     3389/3389
(100 %)
9 diff
(99.8 %id)
TI_1959498585   .a 100 to 1272 51 to 1215       1165/1263
(92 %)
32 diff
(97.5 %id)
TI_1959502621   .a 100 to 1196 53 to 1140       1088/1291
(84 %)
25 diff
(98.1 %id)
DA244807 brain .a 113 to 672 2 to 561   capped   560/560
(100 %)
0 diff
(100 %id)
TI_1948233201   .a 176 to 605 149 to 578       430/456
(94 %)
6 diff
(98.7 %id)
TI_1948233505   .a 176 to 681 126 to 631       506/533
(94 %)
6 diff
(98.9 %id)
TI_1948233658   .a 176 to 632 131 to 587       457/483
(94 %)
6 diff
(98.8 %id)
EL736610 mixed .a 177 to 740 1 to 564       564/564
(100 %)
2 diff
(99.7 %id)
BE001275 breast_normal .a 237 to 452 220 to 4     Submitted on the opposite strand 217/230
(94 %)
6 diff
(97.4 %id)
FN050998 breast carcinoma .a 786 to 884 99 to 1     Submitted on the opposite strand 99/99
(100 %)
0 diff
(100 %id)
TI_1959500253   .a 1277 to 2377 1111 to 15       1097/1248
(87 %)
12 diff
(99.1 %id)
BF915290 uterus_tumor .a 1364 to 1893 16 to 548       537/548
(97 %)
19 diff
(96.6 %id)
DA678503   .a 1378 to 1936 2 to 560   capped   559/559
(100 %)
0 diff
(100 %id)
FN128614 breast carcinoma .a 1415 to 1472 65 to 6     Submitted on the opposite strand 60/66
(90 %)
0 diff
(100 %id)
BQ335104 marrow .a 1506 to 1826 351 to 31       321/351
(91 %)
1 diff
(99.8 %id)
DA022663   .a 1597 to 2072 2 to 477   capped   476/476
(100 %)
1 diff
(99.8 %id)
TI_1959500257   .a 1718 to 2919 1201 to 12       1190/1283
(92 %)
13 diff
(99.0 %id)
DA705654   .a 1721 to 2183 2 to 464   capped   463/463
(100 %)
0 diff
(100 %id)
AW884897 ovary .a 1778 to 2195 429 to 12       418/444
(94 %)
1 diff
(99.8 %id)
AU127930   .a 1882 to 2463 2 to 582   capped   581/583
(99 %)
11 diff
(98.2 %id)
AW837317 leiomios .a 1922 to 2051 138 to 12       127/138
(92 %)
5 diff
(96.4 %id)
BM827395 stomach .a 2279 to 2828 1 to 550       550/550
(100 %)
0 diff
(100 %id)
AA434196 ovarian tumor, ovary .a 3101 to 3396 1 to 296       296/296
(100 %)
1 diff
(99.7 %id)
DB365007   .a 3664 to 4246 579 to 1   tiling clone,   579/589
(98 %)
8 diff
(98.7 %id)
AA434423 ovarian tumor, ovary .a 3844 to 4241 397 to 1   tiling clone,   397/397
(100 %)
2 diff
(99.5 %id)
U69612   .b 1 to 2877 1 to 2877 N695* tiling clone,   2877/2877
(100 %)
5 diff
(99.9 %id)
BM712047 eye, lens .b 2531 to 2970 1 to 435   tiling clone, fully sequenced,   435/435
(100 %)
3 diff
(99.4 %id)
BM670326 eye, lens .b 2940 to 3456 517 to 1   tiling clone, fully sequenced,   517/517
(100 %)
4 diff
(99.3 %id)
BM989580 lung, Metastatic Chondrosarcoma .b 2981 to 3457 477 to 1       477/485
(98 %)
0 diff
(100 %id)
DB542945.
matches multiple genes
hippocampus .b 2998 to 3490 489 to 1     also hits gene IAH1 489/489
(100 %)
4 diff
(99.2 %id)
BG120622 adenocarcinoma, cell line, Liver .b 3020 to 3462 1 to 440       440/999
(44 %)
6 diff
(99.4 %id)
AL043281 testis .b 3034 to 3706 1 to 678   tiling clone,   678/734
(92 %)
15 diff
(98.0 %id)
BX374424 Neuroblastoma Cot 10-normalized .b 3288 to 4206 1 to 918   tiling clone,   918/918
(100 %)
10 diff
(99.0 %id)
AW630994 2 pooled high-grade transitional celltumors, genitourinary tract .b 3422 to 3768 1 to 352       352/352
(100 %)
4 diff
(98.9 %id)
N40799 placenta .b 3481 to 3861 1 to 384   fully sequenced,   384/384
(100 %)
1 diff
(99.8 %id)
AA287409 germinal center B cell .b 3498 to 3943 1 to 446       446/446
(100 %)
5 diff
(98.9 %id)
BF212722 bone marrow, from chronic myelogenous leukemia .b 3516 to 4082 1 to 575       575/575
(100 %)
6 diff
(99.0 %id)
AA303665 aorta .b 3517 to 3780 1 to 267       267/267
(100 %)
4 diff
(98.6 %id)
CB159093 Liver .b 3524 to 4090 1 to 567       567/567
(100 %)
0 diff
(100 %id)
CV374021 placenta_normal .b 3532 to 4066 9 to 541       533/551
(96 %)
13 diff
(97.7 %id)
BM705777 eye, lens .b 3546 to 3952 1 to 410   fully sequenced, Possibly primed on the genome, locally A rich (24/24 A in genome downstream of last aligned base) 410/410
(100 %)
1 diff
(99.8 %id)
CV373092 lung_tumor .b 3562 to 4048 1 to 489       489/489
(100 %)
11 diff
(97.8 %id)
AI919444 anaplastic oligodendroglioma, brain .b 3565 to 3818 254 to 1       254/254
(100 %)
0 diff
(100 %id)
CA439922 lung, Lung Focal Fibrosis .b 3565 to 4235 690 to 19   tiling clone, AAA Possibly primed on the genome, locally A rich (24/24 A in genome downstream of last aligned base) 672/672
(100 %)
1 diff
(99.9 %id)
AI141532 heart .b 3572 to 4135 578 to 15   AAA Possibly primed on the genome, locally A rich (24/24 A in genome downstream of last aligned base) 564/564
(100 %)
0 diff
(100 %id)
AI797833 B-cell, chronic lymphotic leukemia .b 3572 to 4138 567 to 1       567/567
(100 %)
0 diff
(100 %id)
CB069789 Pancreas, Purified pancreatic islet .b 3575 to 3864 1 to 290   fully sequenced,   290/290
(100 %)
3 diff
(99.0 %id)
BE815329 breast_normal .b 3583 to 3918 11 to 346       336/346
(97 %)
6 diff
(98.3 %id)
BF508681   .b 3583 to 3818 253 to 18   AAA Possibly primed on the genome, locally A rich (24/24 A in genome downstream of last aligned base) 236/242
(97 %)
2 diff
(99.2 %id)
H26937 breast .b 3588 to 4026 1 to 452   fully sequenced,   452/452
(100 %)
16 diff
(96.5 %id)
T94027 lung .b 3602 to 3845 1 to 249   fully sequenced,   249/249
(100 %)
3 diff
(98.8 %id)
AA150630 uterus .b 3623 to 3863 1 to 240   fully sequenced,   240/240
(100 %)
1 diff
(99.6 %id)
AW118774 pooled .b 3625 to 4136 512 to 1       512/512
(100 %)
6 diff
(98.9 %id)
TI_154111224   .b 3634 to 4135 624 to 124   AAA Possibly primed on the genome, locally A rich (24/24 A in genome downstream of last aligned base) 501/525
(95 %)
12 diff
(97.8 %id)
AI741293 pooled .b 3636 to 4140 505 to 1       505/505
(100 %)
0 diff
(100 %id)
FN111296 breast carcinoma .b 3647 to 3721 1 to 71       71/71
(100 %)
3 diff
(95.8 %id)
AA811251 germinal center B cell .b 3656 to 4135 496 to 18   AAA Possibly primed on the genome, locally A rich (24/24 A in genome downstream of last aligned base) 479/479
(100 %)
1 diff
(99.8 %id)
CA448354 Chondrosarcoma, Left Pelvis .b 3661 to 4135 493 to 19   AAA Possibly primed on the genome, locally A rich (24/24 A in genome downstream of last aligned base) 475/475
(100 %)
5 diff
(99.0 %id)
AI224134 mixed (see below), Pooled human melanocyte, fetal heart, andpregnant uterus .b 3686 to 4136 450 to 1       450/450
(100 %)
1 diff
(99.8 %id)
AI376698   .b 3689 to 4140 455 to 4       452/455
(99 %)
0 diff
(100 %id)
AA947537 ovary .b 3698 to 4110 1 to 414       414/414
(100 %)
2 diff
(99.6 %id)
AA815133 germinal center B cell .b 3701 to 4014 313 to 1       313/313
(100 %)
8 diff
(97.5 %id)
AI141804 mixed (see below), Pooled human melanocyte, fetal heart, andpregnant uterus .b 3705 to 4136 432 to 1       432/432
(100 %)
0 diff
(100 %id)
BE645266 pooled .b 3711 to 4135 458 to 34   AAA Possibly primed on the genome, locally A rich (24/24 A in genome downstream of last aligned base) 425/425
(100 %)
0 diff
(100 %id)
AI075423 senescent fibroblast .b 3729 to 4140 412 to 1       412/412
(100 %)
0 diff
(100 %id)
CN292573 embryonic stem cell, retinoic acid andmitogen-treated hES cell line H7 .b 3733 to 4151 1 to 419       419/419
(100 %)
0 diff
(100 %id)
AA910834 carcinoid, lung .b 3742 to 4134 393 to 1       393/393
(100 %)
0 diff
(100 %id)
AI911263 pooled .b 3755 to 4236 482 to 1       482/482
(100 %)
0 diff
(100 %id)
AA933982 pooled .b 3757 to 4127 371 to 1       371/371
(100 %)
0 diff
(100 %id)
BF036724 adenocarcinoma, ovary .b 3776 to 4135 1 to 357   AAA Possibly primed on the genome, locally A rich (24/24 A in genome downstream of last aligned base) 357/357
(100 %)
3 diff
(99.2 %id)
AI492870 mixed (see below), Pooled human melanocyte, fetal heart, andpregnant uterus .b 3779 to 4230 452 to 1       452/452
(100 %)
1 diff
(99.8 %id)
AW057613 pooled .b 3779 to 4135 367 to 11   AAA Possibly primed on the genome, locally A rich (24/24 A in genome downstream of last aligned base) 357/357
(100 %)
0 diff
(100 %id)
BF059089 fibrotheoma, ovary .b 3780 to 4244 465 to 1   tiling clone,   465/465
(100 %)
0 diff
(100 %id)
AA827074 germinal center B cell .b 3782 to 4140 363 to 5       359/363
(98 %)
0 diff
(100 %id)
T94779 lung .b 3815 to 4116 304 to 1   fully sequenced,   304/304
(100 %)
0 diff
(100 %id)
AW627690 2 pooled high-grade transitional celltumors, genitourinary tract .b 3818 to 4235 418 to 1       418/418
(100 %)
0 diff
(100 %id)
N27387 placenta .b 3831 to 4139 311 to 1   fully sequenced,   311/311
(100 %)
0 diff
(100 %id)
AA142964 uterus .b 3833 to 4238 396 to 1   fully sequenced,   396/396
(100 %)
2 diff
(99.5 %id)
CB068513 Pancreas, Purified pancreatic islet .b 3834 to 4142 309 to 1   fully sequenced,   309/309
(100 %)
1 diff
(99.7 %id)
AI380147 brain, glioblastoma (pooled) .b 3849 to 4237 390 to 2       389/390
(99 %)
0 diff
(100 %id)
BM678711 eye, fetal eyes, lens, eye anterior segment,optic nerve, retina, Retina Foveal and Macular, RPE andChoroid .b 3856 to 4237 398 to 17       382/398
(95 %)
0 diff
(100 %id)
FN129924 breast carcinoma .b 3862 to 3975 1 to 115       115/120
(95 %)
2 diff
(98.4 %id)
AA884442 pooled .b 3872 to 4237 367 to 2       366/367
(99 %)
0 diff
(100 %id)
AA377312 small intestine .b 3881 to 4135 1 to 254       254/254
(100 %)
1 diff
(99.7 %id)
AW954486   .b 3882 to 4134 1 to 253       253/331
(76 %)
7 diff
(97.9 %id)
BU198020 ectopic and normal uterine endometrium .b 3916 to 4134 220 to 2       219/220
(99 %)
0 diff
(100 %id)
BU734977 eye, lens .b 3922 to 4235 330 to 17   fully sequenced, AAA Possibly primed on the genome, locally A rich (24/24 A in genome downstream of last aligned base) 314/314
(100 %)
0 diff
(100 %id)
H28529 breast .b 3996 to 4223 247 to 13   fully sequenced,   235/247
(95 %)
8 diff
(96.8 %id)
FN066875 breast carcinoma .b 4016 to 4135 1 to 121       121/122
(99 %)
7 diff
(94.3 %id)
BX390097 Neuroblastoma Cot 10-normalized .b 4056 to 4235 1 to 177   AAA Possibly primed on the genome, locally A rich (24/24 A in genome downstream of last aligned base) 177/177
(100 %)
4 diff
(97.8 %id)
BC146658 Donated clones,Novartis FGA collection .c -10 to 1870 1 to 1882 exact tiling clone, AAA   1882/1882
(100 %)
1 diff
(100.0 %id)
CN258241 embryonic stem cells, embryoid bodiesderived from H1, H7 and H9 cells .c -8 to 718 1 to 727       727/727
(100 %)
2 diff
(99.8 %id)
BQ429472 testis .c 9 to 790 1 to 797   available from MGC,   797/804
(99 %)
32 diff
(96.1 %id)
GD155203   .c 922 to 980 64 to 6     Submitted on the opposite strand 59/68
(86 %)
0 diff
(100 %id)
AK289829 brain .d 1 to 888 1 to 888   tiling clone,   888/888
(100 %)
0 diff
(100 %id)
DA765952 tongue .d 645 to 1233 2 to 591   tiling clone, capped   590/590
(100 %)
1 diff
(99.9 %id)
BE005034 breast_normal .d 768 to 889 17 to 140       124/140
(88 %)
6 diff
(95.8 %id)
BP326226 prostata .d 1145 to 1727 1 to 584   tiling clone,   584/584
(100 %)
1 diff
(99.9 %id)
BE925884 breast_normal .d 1545 to 2039 500 to 6   tiling clone,   495/500
(99 %)
1 diff
(99.8 %id)
BC062687 testis .e 1 to 1070 1 to 1070 exact tiling clone, available from MGC, AAA   1070/1070
(100 %)
2 diff
(99.9 %id)
BQ010886 placenta .f 1 to 655 668 to 16 D6V I7F L8S S9L L10Y ... tiling clone, AAA   653/653
(100 %)
2 diff
(99.7 %id)
BQ329374 lung_normal .g 1 to 508 575 to 66 Q11P S13R Q15P N25H V42L ... tiling clone,   510/624
(81 %)
13 diff
(98.0 %id)
DA948918 Spleen .h-u 1 to 565 2 to 568   tiling clone, to resequence, capped   567/567
(100 %)
2 diff
(99.7 %id)
DB338497 testis .h-u 34 to 535 1 to 502   tiling clone, Submitted on the opposite strand 502/504
(99 %)
1 diff
(99.9 %id)
BG961127 colon .h-u 166 to 566 15 to 413   tiling clone,   399/413
(96 %)
6 diff
(98.6 %id)
CV379452 bladder_tumor .h-u 1252 to 1750 1 to 498   tiling clone,   498/498
(100 %)
12 diff
(97.6 %id)
BF095320 uterus_tumor .h-u 1485 to 1807 1 to 323   tiling clone,   323/343
(94 %)
3 diff
(99.2 %id)
TI_1959498599   .h-u 1748 to 2939 1257 to 72   tiling clone,   1186/1301
(91 %)
0 diff
(100 %id)
H30173 breast .h-u 2113 to 2493 1 to 389   tiling clone,   389/434
(89 %)
11 diff
(97.5 %id)
BX370120 Placenta Cot 25-normalized .h-u 2251 to 2849 1 to 608   tiling clone,   608/1033
(58 %)
26 diff
(97.5 %id)
DB333675 Spleen .h-u 2448 to 2988 547 to 1   to resequence,   547/547
(100 %)
7 diff
(98.8 %id)
BM463206 embryonal carcinoma, cell line, testis .h-u 2449 to 2988 31 to 565   AAA Possibly primed on the genome, locally A rich (24/24 A in genome downstream of last aligned base) 535/565
(94 %)
6 diff
(99.0 %id)
CN258240 embryonic stem cells, cell lines H1, H7, andH9 .h-u 2450 to 2921 1 to 471       471/471
(100 %)
7 diff
(98.6 %id)
TI_149306673   .h-u 2527 to 2988 559 to 98   AAA Possibly primed on the genome, locally A rich (24/24 A in genome downstream of last aligned base) 462/966
(47 %)
6 diff
(99.4 %id)
BM978746 lung, Primary Lung Epithelial Cells .h-u 2527 to 3006 480 to 1   tiling clone,   480/488
(98 %)
6 diff
(98.8 %id)
AV760433 bone marrow .h-u 2532 to 2988 123 to 578   AAA Possibly primed on the genome, locally A rich (24/24 A in genome downstream of last aligned base) 456/578
(78 %)
6 diff
(99.0 %id)
AI095477 uterus .h-u 2534 to 2988 455 to 1   tiling clone,   455/455
(100 %)
0 diff
(100 %id)
AA862987 Kidney .h-u 2617 to 2993 376 to 1       376/378
(99 %)
1 diff
(99.8 %id)
H28287 breast .h-u 2682 to 2923 252 to 5       248/252
(98 %)
0 diff
(100 %id)
AW082359 pooled .h-u 2708 to 2992 285 to 1       285/285
(100 %)
5 diff
(98.3 %id)
AA947381 ovary .h-u 2714 to 2988 38 to 314   AAA Possibly primed on the genome, locally A rich (24/24 A in genome downstream of last aligned base) 277/314
(88 %)
6 diff
(98.1 %id)
AI676046 Prostate .h-u 2718 to 2995 279 to 1       279/279
(100 %)
1 diff
(99.7 %id)
EH348994   .h-u 2752 to 2822 1 to 71       71/71
(100 %)
0 diff
(100 %id)
BF037159 adenocarcinoma, ovary .h-u 2774 to 2988 1 to 214   AAA Possibly primed on the genome, locally A rich (24/24 A in genome downstream of last aligned base) 214/214
(100 %)
4 diff
(98.2 %id)
EC483937 Prostate .h-u 2861 to 2955 1 to 95       95/95
(100 %)
1 diff
(99.0 %id)
BE161189 head_neck .j 1 to 467 467 to 1 D6V Q20L P29L H42L tiling clone, Submitted on the opposite strand 467/467
(100 %)
6 diff
(98.8 %id)
AW368444 head_neck Gene ADAM17, variant not shown              
AY422721   Gene ADAM17, variant not shown         Suspected internal deletion, this clone was ignored    
BX339672 Placenta Cot 25-normalized Gene ADAM17, variant not shown         This clone was ignored    
CV371057 uterus Gene ADAM17, variant not shown         Suspected internal deletion, this clone was ignored    
? Gene Summary Gene on genome mRNA:.a, .b, .c, .d, .e, .f, .g, .h-u, .i-u, .j Alternative mRNAs features, proteins, introns, exons, sequences Expression Tissue Function, regulation, related genes DCI