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Nature of Genome:
General Host Type:
Morphology:

positive-stranded ssRNA
Invertebrates
not enveloped, isometric


Family

00.105.  Not assigned

Negative contrast electron micrograph of isometric particles of an isolate of Infectious flacherie virus. The bar represents 100 nm (Courtesy of H. Bando)
 

Taxonomic Structure of the Family

 

Family         00.105. Not assigned
Genus                      00.105.0.01. Iflavirus


Genus

00.105.0.01.   Iflavirus

Type Species

00.105.0.01.001.     Infectious flacherie virus

List of Species Demarcation Criteria in the Genus

The list of species demarcation criteria is:
  • Natural host range: species can be differentiated on the basis of their natural host range
  • Sequence identity between the CPs of isolates and strains of a species is above 90%.
  • List of Species in the Genus

    The ICTVdB virus code and the viruses. Official virus species names are in italics. Tentative virus species names, alternative names ( ), isolates, strains, serotypes, subspecies, or rejected names are not italicized.
     
    Virus codes, virus names, genome sequence accession numbers [ ] and assigned abbreviations ( ), are:

    Species, their serotypes, strains and isolates

    00.105.0.01.001.

    Infectious flacherie virus

    00.105.0.01.001.00.001.

        Infectious flacherie virus

    [AB000906]

    (IFV)

    00.105.0.01.003.

    Perina nuda virus

    00.105.0.01.003.00.001.

        Perina nuda virus

    [AF323747]

    (PnV)

    00.105.0.01.003.00.001.

        (Perina nuda picorna-like virus)

    00.105.0.01.002.

    Sacbrood virus

    00.105.0.01.002.00.001.

        Sacbrood virus

    [AF469603]

    (SBV)










    Tentative Species in the Genus

    None reported.

    Similarity with other Taxa

    Members of the genus Iflavirus have similarities to other viruses with positive sense ssRNA genomes within the picornavirus "superfamily" (Comoviridae, Dicistroviridae, Picornaviridae, Potyviridae and Sequiviridae). For instance the gene order of the nonstructural proteins is the same for all groups within this assemblage i.e. Hel-Pro-Rep.

    However, in many respects the iflaviruses superficially appear to be entomogenous picornaviruses. The genome organization (with the structural proteins located at the 5'end of the genome), three CPs, a single ORF and no sgRNAs, all point to strong affinities with the picornaviruses. However, there are some important differences between the iflaviruses and the picornaviruses. First, the position of VP4 in the CPs is very different from the picornaviruses and suggests an affinity with the dicistroviruses. Second the very small size of the 5'-UTR - which is much smaller than that of either the picornaviruses or the dicistroviruses - may well indicate the lack of an IRES-like element in this region which would make this group unique amongst the animal-infecting members of the "picornavirus-like superfamily".

    In addition to the known members of this genus and the Dicistroviridae there are a large number of viruses of insects/invertebrates with icosahedral/spherical particles, 3 major CPs and ssRNA genomes. While many have been described as either picornaviruses or picorna-like viruses many remain relatively uncharacterized. In the case of Acyrthosiphon pisum virus (APV) [AF14514], the complete genome has been sequenced. This virus has a structural and genomic organization, which are quite different from any other. Among the remaining 20 or so picorna-like viruses of insects there are undoubtedly a number of viruses that will eventually be aligned with members of the genus Iflavirus but which are currently classified as unassigned viruses.

    DERIVATION OF NAMES

    Derivation of Names

    Ifla: a sigla from the type virus of the genus Infectious flacherie virus

    References

    Collated from VIIIth ICTV Report

    Contributed by


    Cite this publication as: Index of Viruses - Iflavirus (2006). In: ICTVdB - The Universal Virus Database, version 4. Büchen-Osmond, C (Ed), Columbia University, New York, USA. http://www.ncbi.nlm.nih.gov/ICTVdb/Ictv/fs_index.htm

    Version 4 is based on Virus Taxonomy, Classification and Nomenclature of Viruses, 8th ICTV Report of the International Committee on Taxonomy of Viruses. Fauquet, CM, Mayo, MA, Maniloff, J, Desselberger, U, and Ball, LA (EDS) (2005) Elsevier/Academic Press, pp. 1259.


    Additional References

    Reference List from the 8th ICTV Report
    ICTVdB taxon description
    ICTVdB Picture Gallery

    References to sequence databases at GenBank and PubMed Central:
    PubMed Central References; nucleotide sequences; complete genomes




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