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Nature of Genome: |
positive-stranded ssRNA
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Family |
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Taxonomic Structure of the Family |
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Family 00.105. Not assigned |
00.105.0.01. Iflavirus |
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00.105.0.01.001. Infectious flacherie virus |
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The ICTVdB virus code and the viruses. Official virus species names are in italics. Tentative virus species
names, alternative names ( ), isolates, strains, serotypes, subspecies, or rejected names are not italicized.
Virus codes, virus names, genome sequence accession numbers [ ] and assigned abbreviations ( ), are:
(IFV) | |||
(PnV) | |||
(SBV) |
None reported.
Members of the genus Iflavirus have similarities to other viruses with positive sense ssRNA genomes within the picornavirus "superfamily" (Comoviridae, Dicistroviridae, Picornaviridae, Potyviridae and Sequiviridae). For instance the gene order of the nonstructural proteins is the same for all groups within this assemblage i.e. Hel-Pro-Rep.
However, in many respects the iflaviruses superficially appear to be entomogenous picornaviruses. The genome organization (with the structural proteins located at the 5'end of the genome), three CPs, a single ORF and no sgRNAs, all point to strong affinities with the picornaviruses. However, there are some important differences between the iflaviruses and the picornaviruses. First, the position of VP4 in the CPs is very different from the picornaviruses and suggests an affinity with the dicistroviruses. Second the very small size of the 5'-UTR - which is much smaller than that of either the picornaviruses or the dicistroviruses - may well indicate the lack of an IRES-like element in this region which would make this group unique amongst the animal-infecting members of the "picornavirus-like superfamily".
In addition to the known members of this genus and the Dicistroviridae there are a large number of viruses of insects/invertebrates with icosahedral/spherical particles, 3 major CPs and ssRNA genomes. While many have been described as either picornaviruses or picorna-like viruses many remain relatively uncharacterized. In the case of Acyrthosiphon pisum virus (APV) [AF14514], the complete genome has been sequenced. This virus has a structural and genomic organization, which are quite different from any other. Among the remaining 20 or so picorna-like viruses of insects there are undoubtedly a number of viruses that will eventually be aligned with members of the genus Iflavirus but which are currently classified as unassigned viruses.
DERIVATION OF NAMESIfla: a sigla from the type virus of the genus Infectious flacherie virus
Collated from VIIIth ICTV Report
Version 4 is based on Virus Taxonomy, Classification and Nomenclature of Viruses, 8th ICTV Report of the International Committee on Taxonomy of Viruses. Fauquet, CM, Mayo, MA, Maniloff, J, Desselberger, U, and Ball, LA (EDS) (2005) Elsevier/Academic Press, pp. 1259.
Comments to ICTVdB
Management
by Cornelia
Büchen-Osmond
Copyright © 2002 International Committee on Taxonomy of Viruses. All rights reserved.