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Descriptions are generated automatically from the ICTVdB database including links. Some descriptions are only very basic and links may point to documents that are not yet published on the Web.

03.019.0.01.014.00.044.003. SARS-Coronavirus AS

Cite this publication as: Sara Mullins for ICTVdB Management (2005). 03.019.0.01.014.00.044.003. SARS-Coronavirus AS. In: ICTVdB - The Universal Virus Database, version 3. Büchen-Osmond, C. (Ed), ICTVdB Management, Columbia University, New York, USA

Cite this site as: ICTVdB - The Universal Virus Database, version 3. http://www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/

Isolation Details

Isolate designation: AS.
Isolation date: March; 2003.
Location: China.
Source of isolate: human.

Virus was isolated by Prof Claudia Balotta; Institute of Infectious and Tropical Diseases, L. Sacco Hospital; University of Milan; Via G.B. Grassi 74; Milan; 20157; Italy. Email: claudia.balotta@unimi.it . Involved in the submission of the isolate was also Prof. Stefano Corvasce; Institute of Infectious and Tropical Diseases, L. Sacco Hospital, University of Milan, Milan, Italy. stefano.corvasce@unimi.it; Prof. Michela Barbara Violin; Institute of Infectious and Tropical Diseases, L. Sacco Hospital, University of Milan, Milan, Italy. michela.violin@unimi.it; Prof. Massimo Galli; Institute of Infectious and Tropical Diseases, L. Sacco Hospital, University of Milan, Milan, Italy. massimo.galli@unimi.it.

Reference: unpublished.

Classification

This is a description of a vertebrate virus at the isolate level.

ICTVdB Virus Code: 03.019.0.01.014.00.044.003. Virus accession number: SARSI001. Former accession number: 41C72D46. NCBI Taxonomy ID: [248485].

Name, Synonyms and Lineage

Virus is assigned to species 03.019.0.01.014. Severe acute respiratory syndrome coronavirus. Virus is assigned to the genus 03.019.0.01. Coronavirus , family 03.019. Coronaviridae , order 03. Nidovirales.

Depositories and Collections

The isolate is unavailable.

Nucleic Acid

The genome is not segmented and consists of a single molecule of linear, positive-sense, single-stranded RNA. The complete genome is 29711 nucleotides long. The RNA has been fully sequenced and complete sequence is 29711 nucleotides long; sequence can be accessed at GenBank with the accession number [AY427439]. The genome has been found to encode open reading frames (orf3a, orf3b, orf6, orf7a, orf7b, orf8a, orf8b, orf9b), spike protein, nucleocapsid, envelope, membrane.

Biological Properties

Natural Host Range

Viral hosts belong to the Domain Eucarya.

Domain Eucarya Kingdom Animalia.

Kingdom Animalia Phylum Chordata.

Phylum Vertebrata Subphylum Vertebrata.

Class Mammalia.

Class Mammalia Order Primates;
Family Hominidae; virus infects Homo sapiens (human).

Host and isolation details Virus was isolated from an adult. Virus was isolated from sputum sample.

General Symptoms in Animals Infection can affect the respiratory system. Signs and symptoms include dyspnoea or wheezing (positive chest radiograph).

Severity and Occurrence of Disease

Host 1: Infection is apparent and clinically expressed.

Comments

Dr. Corvasce, who participated in the sequencing of SARS-CoV AS, does not consider it an isolate but rather a primary sample. However, half of the sputum sample.

Contributor

Data have been submitted online to ICTVdB on 01-12-05 by
Sara Mullins
American Type Culture Collection
George Mason University
PW II, 10801 University Boulevard
Manassas, VA 20110
United States of America
Tel: + 703-365-2700.
Fax: + 703-365-2701.
Email: Sara Mullins.

The description has been generated automatically from DELTA files.

ICTVdB - The Universal Virus Database, developed for the International Committee on Taxonomy of Viruses (ICTV) by Dr Cornelia Büchen-Osmond, is written in DELTA. The virus descriptions in ICTVdB are coded by ICTV members and experts, or by the ICTVdB Management using data provided by the experts, the literature or the latest ICTV Report. The character list is the underlying code. All virus descriptions are based on the character list and natural language translations from the encoded descriptions are automatically generated and formatted for display on the Web.

Developer of the DELTA software: M. J. Dallwitz, T. Paine and E. Zurcher

ICTVdB and DELTA related References

Last updated:15 March 2005 by Cornelia Büchen-Osmond
Web Page generated from ICTVdB by the DELTA systems.

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