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Descriptions are generated automatically from the ICTVdB database including links. Some descriptions are only very basic and links may point to documents that are not yet published on the Web.

90.001.0.01.001. Scrapie agent

Cite this publication as: ICTVdB Management (2006). 90.001.0.01.001. Scrapie agent. In: ICTVdB - The Universal Virus Database, version 3. Büchen-Osmond, C. (Ed), Columbia University, New York, USA

Cite this site as: ICTVdB - The Universal Virus Database, version 3. http://www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/

Table of Contents

Classification

This is a description of a vertebrate prion at the species level.

ICTVdB Virus Code: 90.001.0.01.001. Virus accession number: 90001101. Obsolete virus code: 59.0.1.0.001.; superceded accession number: 59000001.

Name, Synonyms and Lineage

Virus is an ICTV approved species. Virus is of the family 90.001. Prion.

Virion Properties

Symptoms in the host are well established but the causative agent has not yet been clearly determined (as such).

Rod-shaped particles are visible in microsomal membranes of infected brain cells and infectious vesicles found in enriched microsomal preparations, but there is no evidence for an essential nucleic acid within the particles. Isolated material is rod-shaped, but not considered to be the infective entity. Particles do not contain nucleic acid.

Physicochemical and Physical Properties

Under in vitro conditions virions are relatively stable in acid environment of pH 5; relatively stable in alkaline environment of pH 8. Virions are relatively stable in presence of Mg++, and Mn++. Virions are not sensitive to treatment with organic solvents, formaldehyde, and oxidizing agents. The infectivity is not affected by irradiation; retained when deproteinized with proteases.

Proteins

Proteins constitute about 100% of the particle weight; have been identified. Particles are made up of 1 proteins.

Biological Properties

Natural Host

Domain
Viral hosts belong to the Domain Eucarya.

Domain Eucarya
Kingdom Animalia.

Kingdom Animalia
Phylum Chordata.

Phylum Vertebrata
Subphylum Vertebrata; Class Mammalia.

Class Mammalia Order Artiodactyla;
Family Bovidae: Subfamily Caprinae; virus infects Genus Ovis aries (sheep).

References

The following generic references are cited in the most recent ICTV Report.



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DELTA - DEscription Language for TAxonomy developed by Dr Mike Dallwitz, Toni Paine and Eric Zurcher, CSIRO Entomology, Canberra, Australia. ICTVdB - The Universal Virus Database, developed for the International Committee on Taxonomy of Viruses by Dr Cornelia Büchen-Osmond is written in DELTA. The virus descriptions in ICTVdB are coded by, or using data from experts in the field of virology or members ICTV. The character list is the underlying code. All virus descriptions are based on the character list and natural language translations are automatically generated and formatted for display on the Web from the descriptions in DELTA-format. The description has been generated automatically from DELTA files. DELTA - DEscription Language for TAxonomy developed by Dr Mike Dallwitz, Toni Paine and Eric Zurcher, CSIRO Entomology, Canberra, Australia.

ICTVdB - The Universal Virus Database, developed for the International Committee on Taxonomy of Viruses (ICTV) by Dr Cornelia Büchen-Osmond, is written in DELTA. The virus descriptions in ICTVdB are coded by ICTV members and experts, or by the ICTVdB Management using data provided by the experts, the literature or the latest ICTV Report. The character list is the underlying code. All virus descriptions are based on the character list and natural language translations from the encoded descriptions are automatically generated and formatted for display on the Web.

Developer of the DELTA software: M. J. Dallwitz, T. Paine and E. Zurcher

ICTVdB and DELTA related References

Comments to ICTVdB Management
Last updated on 25 April 2006 by Cornelia Büchen-Osmond
Copyright © 2002    International Committee on Taxonomy of Viruses.    All rights reserved.


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