Descriptions are
generated automatically from the ICTVdB database including links. Some
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yet published on the Web.
01.062.0.01.
Vesiculovirus
Cite this publication as: ICTVdB Management
(2006). 01.062.0.01. Vesiculovirus. In: ICTVdB - The Universal Virus
Database, version 4. Büchen-Osmond, C. (Ed), Columbia University, New
York, USA
Cite this site as: ICTVdB - The Universal Virus
Database, version 4.
http://www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/
This is a description of a
vertebrate virus at the genus level.
ICTVdB Virus Code: 01.062.0.01. Virus accession number:
062001GE. Obsolete virus code: 62.0.1.; superceded accession number: 62010000.
NCBI Taxon Identifier NCBI Taxonomy ID:
11271.
Name, Synonyms and Lineage
Synonym(s): Vesicular
stomatitis virus group. Virus is of the family
01.062.
Rhabdoviridae; order
01.
Mononegavirales.
Virions consist of an envelope and a nucleocapsid. Virus
capsid is enveloped. Virions are bullet-shaped. Virions measure
45-100 nm in diameter; 100-430 nm in length. Surface
projections are densely dispersed, distinctive spikes
that cover the whole surface except for the quasi-planar end. Some viruses
are distinctly larger than the type species. Capsid/nucleocapsid is elongated
and exhibits helical symmetry. The nucleocapsid is
uncoiled filamentous, or cylindrical (coiled, is cross-banded with a
length of uncoiled about 700 nm and a width of uncoiled 20 nm, or 30-70 nm.
Virions have a buoyant density in sucrose of 1.19-1.2 g
cm-3.
The Mr
of the genome constitutes 1-2% of the virion by weight. The genome is not
segmented and contains a single molecule of linear,
negative-sense, single-stranded RNA. The complete
genome is 11200 nucleotides long. Nucleotide sequences at the 3'-terminus
are are inverted and complementary to similar regions on the 5' end. The
5'-terminal sequence has conserved regions (with a UUGUCNNUAG sequence at
the beginning of each gene and following the intergenic sequences that templates
the 5' end of the next mRNA apices). The 3'-terminus has conserved
nucleotide sequences; in species of same genus; sequence has conserved regions
(with a AUACUUUUUUU sequence preceding each intergenic region, sequence has
includes about 50 nucleotides in length (leader sequence that precedes N). Each
virion contains a full length copy, or shorter copies.
GenBank records for
nucleotide sequences;
complete genome sequences.
Proteins
constitute about 65-75% of the particle weight (structural).
The viral genome encodes structural proteins and non-structural proteins.
Lipids are
present and located in the envelope and protein (G that has a
covalently associated fatty acid proximal to the lipid envelope). Virions are
composed of 15-25% lipids by weight. The composition of viral lipids and
host cell membranes are similar. The lipids are of host origin and
are derived from host cell membranes. Viral membranes include 55-60%
phospholipids, sterols, and glycolipids.
Polyamines
Other compounds that have been detected in the virus
particles are 3% carbohydrates.
Transcription: Viral mRNAs have common
5'-terminal sequences. With a m7Gpp(m)Am-A(m)CAGNNAUC... motive.
Natural Host
Virus infects during its life cycle a single type of vertebrate host.
Domain
Viral hosts belong to the Domain Eucarya.
Domain Eucarya
Kingdom Animalia.
Kingdom Animalia
Phylum Chordata.
Phylum Vertebrata
Subphylum Vertebrata; Class Mammalia.
Class Mammalia
Order Primates;
Family
Hominidae.
Virus infects Homo sapiens (human).
Type species 01.062.0.01.001.
Vesicular stomatitis Indiana virus 1
.
List of Species in the
Genus.
Tentative Species in the
Genus.
Data Sources and
Contributions
The
following generic references are cited in the most recent ICTV Report.
PubMed References.
Taxonomic Proposals and Changes
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