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Descriptions are generated automatically from the ICTVdB database including links. Some descriptions are only very basic and links may point to documents that are not yet published on the Web.

00.050.1.03.002. Adeno-associated virus 1

Cite this publication as: ICTVdB Management (2006). 00.050.1.03.002. Adeno-associated virus 1. In: ICTVdB - The Universal Virus Database, version 4. Büchen-Osmond, C. (Ed), Columbia University, New York, USA

Cite this site as: ICTVdB - The Universal Virus Database, version 4. http://www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/

Table of Contents

Classification

This is a description of a vertebrate virus at the species level.

ICTVdB Virus Code: 00.050.1.03.002. Virus accession number: 50103002. Obsolete virus code: 50.1.3.0.002; superceded accession number: 50130002.
NCBI Taxon Identifier NCBI Taxonomy ID: 85106.

Name, Synonyms and Lineage

ICTV approved acronym: AAV-1. Virus is an ICTV approved species of the genus 00.050.1.03. Dependovirus; subfamily 00.050.1. Parvovirinae in the family 00.050. Parvoviridae.

Virion Properties

Morphology

Virions consist of a capsid. Virus capsid is not enveloped, round with icosahedral symmetry. The nucleocapsid is isometric and has a diameter of 18-22 nm, or 20-26 nm. Capsids appear round. The capsid consists of 60 capsomers, each a quadrilateral 'kite-shaped' wedge. Surface projections are small and surface appears rough.

Capsids can be penetrated by stain and some appear dark in the center.

Nucleic Acid

The genome is not segmented and contains a single molecule of linear negative-sense, or positive-sense, single-stranded DNA. The complete genome is 5000 nucleotides long. The genome has terminally redundant sequences. The genome sequence is repeated at one end, or repeated at both ends. The 5'-terminal sequence has inverted repeats of the 3'-terminus; terminal repeats at the 5'-end are 145 nucleotides long. The 3'-terminus has conserved nucleotide sequences; of 145 nucleotides in length. Populations of mature viruses contain particles with equivalent numbers of positive and negative sense ssDNA . Upon extraction, the complementary DNA strands usually form dsDNA.

GenBank records for nucleotide sequences; complete genome sequences.

Proteins

The viral genome encodes structural proteins.

Lipids

Lipids are absent.

Translation: Virions are associated with helper virus, but independent from its functions during replication (of adenoviruses).

Biological Properties

Natural Host

Virus infects during its life cycle a single type of vertebrate host.
Domain
Viral hosts belong to the Domain Eucarya.

Domain Eucarya
Kingdom Animalia.

Kingdom Animalia
Phylum Chordata.

Phylum Vertebrata
Subphylum Vertebrata.

Class Mammalia.

References

The following generic references are cited in the most recent ICTV Report.

PubMed References.



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DELTA - DEscription Language for TAxonomy developed by Dr Mike Dallwitz, Toni Paine and Eric Zurcher, CSIRO Entomology, Canberra, Australia. ICTVdB - The Universal Virus Database, developed for the International Committee on Taxonomy of Viruses by Dr Cornelia Büchen-Osmond is written in DELTA. The virus descriptions in ICTVdB are coded by, or using data from experts in the field of virology or members ICTV. The character list is the underlying code. All virus descriptions are based on the character list and natural language translations are automatically generated and formatted for display on the Web from the descriptions in DELTA-format. The description has been generated automatically from DELTA files. DELTA - DEscription Language for TAxonomy developed by Dr Mike Dallwitz, Toni Paine and Eric Zurcher, CSIRO Entomology, Canberra, Australia.

ICTVdB - The Universal Virus Database, developed for the International Committee on Taxonomy of Viruses (ICTV) by Dr Cornelia Büchen-Osmond, is written in DELTA. The virus descriptions in ICTVdB are coded by ICTV members and experts, or by the ICTVdB Management using data provided by the experts, the literature or the latest ICTV Report. The character list is the underlying code. All virus descriptions are based on the character list and natural language translations from the encoded descriptions are automatically generated and formatted for display on the Web.

Developer of the DELTA software: M. J. Dallwitz, T. Paine and E. Zurcher

ICTVdB and DELTA related References

Comments to ICTVdB Management
Last updated on 25 April 2006 by Cornelia Büchen-Osmond
Copyright © 2002    International Committee on Taxonomy of Viruses.    All rights reserved.


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