[Home] [ICTV Taxonomy - Index of Viruses] [Virus Descriptions] [Character List] [Picture Gallery]
[Tutorial] [Online Data Retrieval & Identification] [Virus Isolate Registration & Submission] [Search]
Descriptions are generated automatically from the ICTVdB database including links. Some descriptions are only very basic and links may point to documents that are not yet published on the Web.

00.046.0.03.001.00.000.001. Thogoto virus, SiAr126 virus strain

Cite this publication as: ICTVdB Management (2006). 00.046.0.03.001.00.000.001. Thogoto virus, SiAr126 virus strain. In: ICTVdB - The Universal Virus Database, version 4. Büchen-Osmond, C. (Ed), Columbia University, New York, USA

Cite this site as: ICTVdB - The Universal Virus Database, version 4. http://www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/

Table of Contents

Isolate Description

Isolate designation: SiAr 126.

Biocontainment Level

Distribution of this virus falls under quarantine restrictions. It is recommended to handle this virus at the biocontainment level BSL-3.

Classification

This is a description of an invertebrate or vertebrate virus at the isolate level.

ICTVdB Virus Code: 00.046.0.03.001.00.000.001. Virus accession number: 460031S1.
NCBI Taxonomy Identifier Taxon ID: 126796.

Name, Synonyms and Lineage

Virus is assigned to species Thogoto virus of the genus 00.046.0.03. Thogotovirus in the family 00.046. Orthomyxoviridae.

Virion Properties

Morphology

Virions consist of an envelope, a matrix protein, a nucleoprotein complex, a nucleocapsid, and a polymerase complex. Virus capsid is enveloped. Virions are spherical to pleomorphic; filamentous forms occur. Virions measure 80-120 nm in diameter; 200-300 nm in length. The envelope surrounds one nucleocapsid. Surface projections are densely dispersed, distinctive spikes that cover the surface evenly and comprise esterase-esterase. Surface projections are 10-14 nm long; 4-6 nm in diameter. Capsid/nucleocapsid is elongated with helical symmetry. The nucleocapsid is helical; and segments have different size classes with a length of 50-130 nm. The nucleocapsids are segmented with loops at one end.

Physicochemical and Physical Properties

The molecular mass (Mr) of virions is 250 x 106. Virions have a buoyant density in sucrose of 1.19 g cm-3. The sedimentation coefficient is 700-800 S20w (for non-filamentous particles). Virions are sensitive. Virions are sensitive to treatment with heat, lipid solvents, non-ionic detergents, formaldehyde, oxidizing agents. The infectivity is reduced after exposure to irradiation.

Nucleic Acid

The genome is segmented and consists of six segments of linear negative-sense, single-stranded RNA. The complete genome is 10000 nucleotides long. The segment 1. Segment 2. Segment 3 is fully sequenced, complete sequence is 1865 nucleotides long and has the accession number [D00540]. Segment 4 has been fully sequenced, complete sequence is 1574 nucleotides long, has the accession number [M77280]. The 5'-terminal sequence has conserved regions and repeats complementary to the 3'-terminus; terminal repeats at the 5'-end are 14 nucleotides long. The multipartite genome is encapsidated, each segment in a separate nucleocapsid, and the nucleocapsids are surrounded by one envelope.

GenBank records for nucleotide sequences; complete genome sequences.

Proteins

The viral genome encodes structural proteins and non-structural proteins.

Biological Properties

Natural Host

Virus infects during its life cycle arthropod and vertebrate hosts. Domain
Viral hosts belong to the Domain Eucarya.

Domain Eucarya
Kingdom Animalia.

Kingdom Animalia
Phylum Arthropoda, or Chordata.

Phylum Arthropoda
Subphylum Hexapoda.

Phylum Vertebrata
Subphylum Vertebrata; Class Mammalia.

Class Mammalia Order Primates;
Family Hominidae.
Virus infects Homo sapiens (human).

Transmission and Vector Relationships

Virus is transmitted by a vector in a direct manner. Virus is transmitted by contact between hosts.

Vector Transmission:
Virus is transmitted by arthropods; arthropod-borne virus is transmitted by arachnids; arthropod-borne virus is transmitted by ticks. Virus is transmitted in a non-persistent manner; retained when the vector moults; replicates in the vector.

References

PubMed References.



Limit search to: Title & Body Title Document Path
Show Reverse Sort

DELTA - DEscription Language for TAxonomy developed by Dr Mike Dallwitz, Toni Paine and Eric Zurcher, CSIRO Entomology, Canberra, Australia. ICTVdB - The Universal Virus Database, developed for the International Committee on Taxonomy of Viruses by Dr Cornelia Büchen-Osmond is written in DELTA. The virus descriptions in ICTVdB are coded by, or using data from experts in the field of virology or members ICTV. The character list is the underlying code. All virus descriptions are based on the character list and natural language translations are automatically generated and formatted for display on the Web from the descriptions in DELTA-format. The description has been generated automatically from DELTA files. DELTA - DEscription Language for TAxonomy developed by Dr Mike Dallwitz, Toni Paine and Eric Zurcher, CSIRO Entomology, Canberra, Australia.

ICTVdB - The Universal Virus Database, developed for the International Committee on Taxonomy of Viruses (ICTV) by Dr Cornelia Büchen-Osmond, is written in DELTA. The virus descriptions in ICTVdB are coded by ICTV members and experts, or by the ICTVdB Management using data provided by the experts, the literature or the latest ICTV Report. The character list is the underlying code. All virus descriptions are based on the character list and natural language translations from the encoded descriptions are automatically generated and formatted for display on the Web.

Developer of the DELTA software: M. J. Dallwitz, T. Paine and E. Zurcher

ICTVdB and DELTA related References

Comments to ICTVdB Management
Last updated on 25 April 2006 by Cornelia Büchen-Osmond
Copyright © 2002    International Committee on Taxonomy of Viruses.    All rights reserved.


Additional access points to virus species lists, descriptions and images on the web:

Species catalogue                     iSpecies.org - a species search engine           a species search engine

Google Analytics      Google Analytics: activity view