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Descriptions are generated automatically from the ICTVdB database including links. Some descriptions are only very basic and links may point to documents that are not yet published on the Web.

00.012.0.03.001. Norwalk virus

Cite this publication as: ICTVdB Management (2006). 00.012.0.03.001. Norwalk virus. In: ICTVdB - The Universal Virus Database, version 4. Büchen-Osmond, C. (Ed), Columbia University, New York, USA

Cite this site as: ICTVdB - The Universal Virus Database, version 4. http://www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/

Table of Contents

Classification

This is a description of a vertebrate virus at the species level with data limited to classification details. If you have primary data on this virus, please submit them to ICTVdB using the online data entry systems or contact the ICTVdB management.

ICTVdB Virus Code: 00.012.0.03.001. Virus accession number: 12003001. Obsolete virus code: 12.0.3.0.001; superceded accession number: 12020001.
NCBI Taxon Identifier NCBI Taxonomy ID: 11983.

Name, Synonyms and Lineage

ICTV approved acronym: NV. Virus is the type of the genus 00.012.0.03. Norovirus of the family 00.012. Caliciviridae; not assigned to an order.Caliciviridae; not assigned to an order.

Virion Properties

Morphology

Virions consist of a capsid. Virus capsid is not enveloped, round with icosahedral symmetry. The isometric capsid has a diameter of 35-39 nm. Capsids appear round to hexagonal in outline. The capsid surface structure reveals a regular pattern with distinctive features. The capsomer arrangement is clearly visible. Capsid with 32 cup-shaped depressions.

Electron micrograph of Norwalk virus courtesy of C.Büchen-Osmond.


























Electron micrograph of Norwalk virus.



















Capsid structures, detailed structural and computational analysis are found in the Protein Data Bank (PDB) using VIPERdB, the VIrus Particle ExploreR 1ihm (1ihm.html).

Nucleic Acid

The genome is not segmented and contains a single molecule of linear positive-sense, single-stranded RNA. The complete genome is 7900 nucleotides long. The 5'-end of the genome has a genome-linked protein (VPg). The 3'-terminus has a poly (A) tract.

GenBank records for nucleotide sequences; complete genome sequences.

Proteins

The viral genome encodes structural proteins.

Lipids

Lipids are not reported.

Genome Organization and Replication

By itself, genomic nucleic acid is infectious.

Biological Properties

Natural Host

Virus infects during its life cycle a single type of vertebrate host.
Domain
Viral hosts belong to the Domain Eucarya.

Domain Eucarya
Kingdom Animalia.

Kingdom Animalia
Phylum Chordata.

Phylum Vertebrata
Subphylum Vertebrata; Class Mammalia.

Class Mammalia Order Primates;
Family Hominidae.
Virus infects Homo sapiens (human).

Ecology, Epidemiology and Control

A fact sheet on this virus is available from the Norwalk virus Centers for Disease Control and Prevention (CDC), National Center for Infectious Diseases (NCID) and Epidemiology and Disease Control Program in (California Judith I. Rosen, RN, MSN, MPH, CIC[/a Infection Control Practitioner, VA Palo Alto Health Care System). Postings on the disease are found in the archive of .
References for sanitation or environmental control:

References

PubMed References.

Images

Taxon images: • Norwalk Virus Electron Micrograph courtesy of B. V. Prasad, Baylor College of Medicine, Houston. • Norwalk virus as groundwater pollutant. • Norwalk virus (Source: EP Williams Enviromental Protection Agency). • em_NLVca.jpg. • EM by Cornelia Büchen-Osmond. • EM from Dave Bhella, University of Glasgow, Scotland. • EM from Dave Bhella, University of Glasgow, Scotland.



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DELTA - DEscription Language for TAxonomy developed by Dr Mike Dallwitz, Toni Paine and Eric Zurcher, CSIRO Entomology, Canberra, Australia. ICTVdB - The Universal Virus Database, developed for the International Committee on Taxonomy of Viruses by Dr Cornelia Büchen-Osmond is written in DELTA. The virus descriptions in ICTVdB are coded by, or using data from experts in the field of virology or members ICTV. The character list is the underlying code. All virus descriptions are based on the character list and natural language translations are automatically generated and formatted for display on the Web from the descriptions in DELTA-format. The description has been generated automatically from DELTA files. DELTA - DEscription Language for TAxonomy developed by Dr Mike Dallwitz, Toni Paine and Eric Zurcher, CSIRO Entomology, Canberra, Australia.

ICTVdB - The Universal Virus Database, developed for the International Committee on Taxonomy of Viruses (ICTV) by Dr Cornelia Büchen-Osmond, is written in DELTA. The virus descriptions in ICTVdB are coded by ICTV members and experts, or by the ICTVdB Management using data provided by the experts, the literature or the latest ICTV Report. The character list is the underlying code. All virus descriptions are based on the character list and natural language translations from the encoded descriptions are automatically generated and formatted for display on the Web.

Developer of the DELTA software: M. J. Dallwitz, T. Paine and E. Zurcher

ICTVdB and DELTA related References

Comments to ICTVdB Management
Last updated on 25 April 2006 by Cornelia Büchen-Osmond
Copyright © 2002    International Committee on Taxonomy of Viruses.    All rights reserved.


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