Launch guide window

Launch NCBI Home Page

Goals

• Find structures using Entrez queries
• Construct advanced queries using Preview/Index.

Steps

1. Begin with Preview/Index in Entrez Structure
   
   • From the NCBI home page, click on the "All Databases" link on the top bar.
   • Click on Structure in the list of databases.
   • Click on Preview/Index to view the list of available fields.

2. Search 1
   
   • Find all protein structures from primates. Use the fields [Organism] and [ProteinChainCount].
   • Add a term to your search to find all structures of protein-DNA complexes from primates containing only double-stranded DNA. Use the field [DnaChainCount].
   • Go to the next step to check your answer.

3. Answer 1
   Click here to check your answer.

4. Search 2
   
   • Using the [LigName] field, extend Search 1 to limit to only those complexes containing a zinc ion.
   • Go to the next step to check your answer.

5. Answer 2
   Click here to check your answer.

6. Search 3
   Find all complexes containing at least one protein chain, one DNA chain, and one RNA chain. First use "all[Filter]" to find all structures, then use terms such as "NOT 0[DnaChainCount]".

7. Answer 3
   Click here to check your answer.

8. Search 4
   
   • Find all structures determined by x-ray diffraction from Archaea at resolutions less than 2.0 Angstroms. Use the ":" range operator as follows: 0.0:2.0[resolution].
   • Use the [Filter] field to limit the results to those structures linked to SNP records, indicating that they are a structural model for a known SNP. Using Index in Preview/Index, look for terms in the [Filter] field such as "structure abc", which find links between structure and database abc.

9. Answer 4
   Click here to check your answer.

10. Search 5
    Find all fungal structures of single RNA chains only with one bound ligand.

11. Answer 5
    Click here to check your answer.

Revised January 4, 2006