Launch guide window

Launch NCBI Home Page

Goals

• Find 3D domain records using Entrez 3D Domains
• Construct advanced queries using Preview/Index

Steps

1. Begin with Preview/Index in Entrez 3D Domains
   
   • From the NCBI home page, click on the "All Databases" link on the top bar.
   • Click on 3D Domains in the list of databases.
   • Click on Preview/Index to view the list of available fields.

2. Search 1
   Find all structures of mammalian proteins containing only 2 helices and 2 strands. Use the fields [helixcount] and [strandcount], and remember to limit [domainno] to 0.

3. Answer 1
   Click here to check your answer.

4. Search 2
   Find all protein structures from green plants with molecular weights greater than 100 kDa. Use a term such as 100000:1000000[molweight].

5. Answer 2
   Click here to check your answer.

6. Search 3
   Find all polypeptide chains containing between 10 and 20 3D domains. First use the [domainno] field and the range operator ":". Example: 5:8[domainno] gives 5-8 3D domains. Find the polypeptide with the largest number of 3D domains. How many does it have?

7. Answer 3
   Click here to check your answer.

8. Search 4
   Find all human 3D Domains deposited to PDB between October 15, 2004 and November 15, 2004. Use the [PDB Deposit Date] field with date format YYYY/MM/DD.

9. Answer 4
   Click here to check your answer.

Revised September 4, 2007