Launch guide window

Launch NCBI Home Page

Goals

• Find the PubChem Compound summary page for sarin
• Learn about the functional properties of sarin
• Retrieve other compounds with the same function as sarin
• Save the compounds in a single combinatorial library file

Steps

1. Retrieve the PubChem Compound Summary page for sarin
   
   • On the NCBI home page, enter sarin in the search box and click Go.
   • Find the PubChem Compound results and click on the number of hits, and then on the CID (Compound IDentifier) for the first record retrieved.

2. Find functional properties of sarin
   
   • According to the Medical Subject Annotations section, what is sarin (unfortunately) used for and what is its mode of action?
   • Under Pharmacological Action, click on the functional class for this compound (hint: not the one about chemical warfare).

3. Find functional analogs of sarin
   
   • Click on the second record (contains [Pharmacological Action]) to see a list of the names of some compounds in this class.
   • Click PubChem Compound with MeSH in the Links menu to access a more comprehensive listing of compounds with the same pharmacological function as sarin.

4. Create and save the sarin combinatorial library
   
   • Choose PubChem Download from the Display menu.
   • Choose your preferred format, then click Download.

Revised August 25, 2006