PubChem Essentials

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 Essentials Exercises

 
   Finding 3D structural complexes: Gleevec

Launch guide window Launch NCBI Home Page

Goals

  • Find compound records for gleevec that are linked to 3D structures
  • View the structural complex in Cn3D

Steps

  1. Search PubChem Compound
    • On the NCBI home page, choose PubChem Compound from the Database menu.
    • Type gleevec in the search box.
    • Click Go.

  2. Limit to records with links to 3D structures
    • Click the Protein3D tab above the record summaries.
    • Click on the small pushpin symbol to reveal the Entrez query that accomplishes this limit.
    • Click on Other Links to the right, then on Protein Structures.

  3. View the structure in Cn3D
    • Click the PDB accession 1XBB.
    • You should see an image of gleevec in the bottom of the structure summary page.
    • Click the View 3D Structure button to launch Cn3D.

Revised October 9, 2007