Protein Analysis
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Searching PROSITE

Access to PROSITE using
  • Quick search by AC, ID, or description. (NO boolean operators).
  • Browse PROSITE documentation entries for
    • Post-translational modifications, Domains, DNA or RNA associated proteins, Enzymes, Electron transport proteins, Other transport proteins, Structural proteins, Receptors, Cytokines and growth factors, Hormones and active peptides, Toxins, Inhibitors, Protein secretion and chaperones and others.
  • SRS - Sequence Retrieval System.
  • Search by author.
  • Search by citation.
  • Search by full text search.
Similarity searching in PROSITE:
  • ScanProsite - Scan a sequence against PROSITE or a pattern against SWISS-PROT or PDB and visualize matches on structures.
    1. Scan a protein for PROSITE matches (Enter a SWISS-PROT/TrEMBL accession number (AC), a sequence identifier (ID), a PDB identifier, or paste your own protein sequence in the box).
    2. Search SWISS-PROT with a PROSITE entry (Enter a PROSITE accession number, or type your pattern in PROSITE format. You can also scan a sequence with the entire PROSITE database).

  • Example: Scan a protein for PROSITE matches using SWISS_PROT entry P35523.
    • Enter the query in the yellow box on the left hand side of the ScanProsite page and click START THE SCAN. What protein motifs can you find? Each entry has a documentation (PDOC12345), and a PROSITE (PS12345) format.

  • Other pattern and profile search tools.

Protein Analysis
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Revised 07/24/2003