Non-Human Genomes
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Eukaryotic genes in prokaryotic genomes

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Is there evidence of Horizontal Gene Transfer from eukaryotes to prokaryotes?

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The presence of eukaryotic homologs in Escherichia coli K12 has been taken by some researchers as an indication of Horizontal Gene Transfer (HGT) from eukaryotes to a prokaryote.

  1. Scroll to Escherichia coli K12 on the list of Microbial Genomes ENTREZ GENOMES and select [T] for TaxTable
  2. Note that there appear to be 9 proteins in Escherichia coli K12 that are homologous to eukaryotic proteins (see FIG 6)
  3. Note also that the TaxPlot for Haemophilus influenzae contains only 2 eukaryotic homologs…

Escherichia coli K12 TaxPlot results

FIG 6: Escherichia coli K12 TaxPlot results


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