Practice User Question: Sequence View of ACTN3 |
| Sample User Question
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Locate the gene ACTN3. Go to the sequence view level. Locate the mRNA start.
Locate the first exon. What are the first five amino acids? How
long is the first intron? Use the sequence viewer to answer.
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| Analysis/Comments |
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While some of this information can be obtained from other resources,
such as the protein and nucleic acid records for this gene, the Sequence
Viewer can also be used to answer these types of questions. The advantage
to the sequence viewer is that it clearly and visually displays the exon/intron
structure of the gene as well as upstream and downstream genomic sequences.
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| Flow Chart |
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MapViewer Search/Browse Page - Use the Genome View search to locate
ACTN3 and open the MapView of this gene. Look for the 'sv' link by
the gene name.
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Sequence Viewer - The Sequence Viewer "sv" is the bottom
zoom level of the MapViewer and shows the genomic sequence at the base pair level
with annotation.
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| Step By Step Guide |
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- On the MapViewer search page, search for ACTN3. Choose the gene locus, not
the STS markers. Open the MapView of the gene.
- Find the 'sv' link to the sequence viewer near the name of the gene on the
Master Map. Click on it.
- Scroll through the Sequence Viewer to locate the first exon and first intron
of this gene. The exons will be shown with amino acids labelled. The intron
may be long and require significant scrolling.
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