| In "classical" expression experiments
such as Northern Blots and 2D Protein Gels it is common to "normalize"
data between samples using the abundances of Beta Actin (cytoplasmic actin-ACTB) RNA or protein. The rational is that Beta Actin is a common "housekeeping" gene and therefore should be expressed at roughly equivalent levels in all tissues. Using both UniGene's (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=unigene) Expression Profile and the Human Protein Atlas (http://www.hpr.se/index.php), determine if this is a valid approach to normalization of RNA and protein expression data accross various tissues.