Entrez Gene
- Entrez Gene provides an efficient means to search for genetic and chromosomal markers
- On the Limits page, under the Limit by Taxomomy header, activate the check box for Homo sapiens to search only for human genes
- Type the word, obesity in the query box
- 171 loci (from any human chromosomes) are retrieved
- to limit retrieval only to loci on chromosome 10, add 10[Chromosome] to your search, so the Boolean representation of the final search would be: obesity[all] AND human[orgn] AND 10[Chromosome]
- Click on any gene symbol to retrieve further information
OMIM
- In the OMIM limits click on the Chromosome 10 box
- Enter obesity in the query box and click on Go
- *603118 discusses suggestive evidence that a major gene on Chromsome 10 is implicated in the development of obesity
- *603118 states that epidemiologic studies suggest that 30-70% may be attributable to genetic factors
- From these same search results, #601665 indicates that major susceptibility to obesity exist on Chromosomes 4, 10 and 20
- Reduced energy expenditure is discussed in record #601665
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