A large number of studies have described an association between ER polymorphisms and osteoporosis. Given the high incidence of osteoporosis in developed countries, should public health agencies advocate for a population screening program?
Comments / Analysis
HuGE reviews are systematic and take a quantitative approach to reviewing the epidemiologic evidence between genes and diseases. Systematic reviews are important to the determination of whether population screening is recommended.
Step By Step Guide
CDC Homepage - HuGENet provides an efficient resource to locate both HuGE Reviews and other systematic reviews.
From the CDC homepage, click on the Genetics and Genomics link
Next, click on the HuGENet link
Click on the link for HuGE Reviews
Click on the link to access the Archives
Click on the link for the heading, Estrogen Receptor Gene Polymorphisms and the Genetics of Osteoporosis
Scroll down until you reach the section titled, Population Testing