Genetics Review
PubMed Entrez BLAST OMIM Taxonomy Structure
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Course Description

Schedule

Introduction

Genetics Review

Types of Databases

Format of Sequence Record

Entrez

BLAST

3-D Structures

Genomes and Maps

Librarian Roles

WWW Sites

Glossaries and Dictionaries

 

Transcription  ...from DNA to RNA back to top

Source:  image from the National Human Genome Research Institute (NHGRI) Genetic Illustrations.

Definition back to top

Transcription is the process of making RNA from DNA.

Since DNA and RNA use the same four letter alphabet made of the bases A,C,T, and G, (except RNA uses U instead of T), copying a gene from DNA onto RNA simply transcribes the instructions for making a protein. It does not translate them into another language or alphabet.

In eukaryotes, DNA remains in the nucleus, but proteins are built in the cytoplasm. So the instructions contained in DNA must be transcribed onto an RNA (ribonucleic acid) molecule, which moves into the cytoplasm and serves as the template for making a protein.

Unlike replication, which makes a copy of a complete chromosome, transcription only makes a copy of the gene that is to be expressed as a protein.

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  Revised September 29, 1999
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