Genetics Review
PubMed Entrez BLAST OMIM Taxonomy Structure
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Course Description

Schedule

Introduction

Genetics Review

Types of Databases

Format of Sequence Record

Entrez

BLAST

3-D Structures

Genomes and Maps

Librarian Roles

WWW Sites

Glossaries and Dictionaries

 

Genome back to top

A genome is all the DNA contained in an organism or a cell, which includes both the chromosomes within the nucleus and the DNA in mitochondria (and DNA in the chloroplasts of plant cells).

Source:  definition from the National Human Genome Research Institute (NHGRI) Glossary of Genetic Terms.

More... back to top

Genome Sizes

The size of genomes vary, as noted in the previous page on chromosomes. For example, the human genome is estimated to contain over 3 billion base pairs, while the E. coli genome contains 4.6 million base pairs.

The Database of Genome Sizes (DOGS) lists the genome sizes (in base pairs) of various organisms.

Karyotypes

A karyotype is an image of a cell showing all the chromosomes within that cell, usually during metaphase of mitosis. Karyotypes can be used to check for chromosomal abnormalities, such as trisomy (three copies of a chromosome rather than two), or chromosomes that are missing pieces or contain extra stretches of DNA.

The Cytogenetics Gallery by the Department of Pathology, University of Washington, Seattle, WA, provides a nice overview of chromosomes and karyotypes.

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  Revised February 9, 2001
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