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Molecular Biology Review: Title slide/table of contents
Prerequisite reading
NHGRI Video: Exploring Our Molecular Selves
Brief review of key terms
(covered in class)
central dogma of biology
cell
prokaryotic
eukaryotic
genome
chromosome
DNA
double helix
complementary strands
plus/minus strand (Watson/Crick; positive/negative)
antiparallel
DNA - detailed view
nucleotide
base pair
5' and 3'
nucleotide base codes (IUPAC)
gene
intron/exon
regulatory region: gene control
transcription
mRNA
primary transcript
splicing, mature mRNA
alternative splicing
translation
codon
start and stop codons
genetic code
degenerate
wobble hypothesis
reading frames
protein
amino acid abbreviations (IUPAC)
amino acid properties
protein domains
structure
primary
secondary
tertiary
quatenary
gene expression
in different organs
in a single organ at different points in time
genetic variation (polymorphisms)
mutations
chromosomal mutations
sequence mutations
Expanded list of important terms
(for your reference -
in development
)
Animation: PER gene transcription/translation
ORF Finder: hands-on
Fields of study
genetics
genomics
proteomics
bioinformatics
References
Slide List for This Module
Molecular Biology Review
Revised 11/01/2007
