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Molecular Biology Review module of the MLA course on Introduction to Molecular Biology Information Resources
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Gene Expression Profile of a Single Organ
at Different Points in Time

 

Gene expression also varies within a certain type of cell at different points in time.

For example, the gene expression profiles of an organ might differ between normal and cancerous states, as shown here.

One goal of the National Cancer Institute's (NCI) Cancer Genome Anatomy Project is to identify the human genes expressed in different cancerous states, based on cDNA (EST) libraries, and to determine the molecular profiles of normal, precancerous, and malignant cells.

Sources:  image from the Cancer Genome Anatomy Project (CGAP), Conceptual Tour, July 21, 2000.
More:  The UniGene Digital Differential Display (DDD) allows you to do comparisons of actual gene expression profiles. Follow the "Try This" examples given in the UniGene DDD guide for stages of prostate cancer.

Molecular Biology Review
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Revised 11/01/2007