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Format of Sequence Record module of the MLA course on Introduction to Molecular Biology Information Resources
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GenPept: Archival Protein Sequence Record

AAC50285:  hMLH1
  • Highlights describe the salient features of the record shown below. They open in a second window so you can look at the record and the highlights side by side.
  • The record is also available live in Entrez (also opens in the second window), where the modification date will show you if the record has changed since it was captured for this web page. It's a good way to see how records evolve, but only after you review the highlights of the record below. The records featured in this module were deliberately captured as static images to save a snapshot of the records in time and show the relationship among them.
  

LOCUS       AAC50285                 756 aa            linear   PRI 29-NOV-1995
DEFINITION  hMLH1.
ACCESSION   AAC50285
VERSION     AAC50285.1  GI:463989
DBSOURCE    locus HSU07343 accession U07343.1
KEYWORDS    .
SOURCE      Homo sapiens
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 756)
  AUTHORS   Bronner,C.E., Baker,S.M., Morrison,P.T., Warren,G., Smith,L.G.,
            Lescoe,M.K., Kane,M., Earibino,C., Lipford,J., Linblom,A.,
            Tannergard,P., Bollag,R.J., Godwin,A.R., Ward,D.C.,
            Nordenskjold,M., Fishel,R., Kolodner,R.D. and Liskay,R.M.
  TITLE     Mutation in the DNA mismatch repair gene homologue hMLH1 is
            associated with hereditary non-polyposis colon cancer
  JOURNAL   Nature 368 (6468), 258-261 (1994)
  MEDLINE   94195398
   PUBMED   8145827
REFERENCE   2  (residues 1 to 756)
  AUTHORS   Morrison,P.T.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-MAR-1994) Paul T. Morrison, Molecular Biology Core
            Facility, Dana-Farber Cancer Institute, 44 Binney Street, Boston,
            MA 002115, USA
COMMENT     Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..756
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3p22-23"
     Protein         1..756
                     /product="hMLH1"
     CDS             1..756
                     /gene="hMLH1"
                     /coded_by="U07343.1:22..2292"
                     /note="homolog of S. cerevisiae PMS1 (Swiss-Prot Accession
                     Number P14242), S. cerevisiae MLH1 (GenBank Accession
                     Number U07187), E. coli MUTL (Swiss-Prot Accession Number
                     P23367), Salmonella typhimurium MUTL (Swiss-Prot Accession
                     Number P14161) and Streptococcus pneumoniae (Swiss-Prot
                     Accession Number P14160)"
ORIGIN
        1 msfvagvirr ldetvvnria ageviqrpan aikemiencl dakstsiqvi vkegglkliq
       61 iqdngtgirk edldivcerf ttsklqsfed lasistygfr gealasishv ahvtittkta
      121 dgkcayrasy sdgklkappk pcagnqgtqi tvedlfynia trrkalknps eeygkilevv
      181 grysvhnagi sfsvkkqget vadvrtlpna stvdnirsif gnavsrelie igcedktlaf
      241 kmngyisnan ysvkkcifll finhrlvest slrkaietvy aaylpknthp flylsleisp
      301 qnvdvnvhpt khevhflhee silervqqhi eskllgsnss rmyftqtllp glagpsgemv
      361 ksttsltsss tsgssdkvya hqmvrtdsre qkldaflqpl skplssqpqa ivtedktdis
      421 sgrarqqdee mlelpapaev aaknqslegd ttkgtsemse krgptssnpr krhredsdve
      481 mveddsrkem taactprrri inltsvlslq eeineqghev lremlhnhsf vgcvnpqwal
      541 aqhqtklyll nttklseelf yqiliydfan fgvlrlsepa plfdlamlal dspesgwtee
      601 dgpkeglaey iveflkkkae mladyfslei deegnliglp llidnyvppl eglpifilrl
      661 atevnwdeek ecfeslskec amfysirkqy iseestlsgq qsevpgsipn swkwtvehiv
      721 ykalrshilp pkhftedgni lqlanlpdly kvferc
//
 

Format of Sequence Record
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Revised 11/01/2007